GEO DataSets

(Submitter supplied) Genetic deletion of Nfatc1 in mice results in profound osteoclast-poor osteopetrosis, a high bone mass state caused by a lack of osteoclast activity. We hypothesized that the family of NFATc1 regulated transcripts in the osteoclast would be enriched for genes associated with osteoclast function. We used microarrays profile gene expression in wild-type and NFATc1-deficient osteoclasts generated in vitro to identify NFATc1-dependent transcripts in osteoclasts.

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS5464

Platform:

GPL8321

4 Samples

Download data: CEL

Analysis of osteoclasts lacking the transcription factor NFATc1. Osteoclasts cultured in the presence of M-CSF and RANKL to induce differentiation. Results identify gene targets of NFATc1 in osteoclastogenesis.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL8321

Series:

GSE37219

4 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Mouse Genome 430A 2.0 Array is a single array representing approximately 14,000 well-characterized mouse genes that can be used to explore biology and disease processes. more...

Organism:

Mus musculus

66 DataSets

522 Series

2 Related Platforms

6848 Samples

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