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Items: 6

1.

Gene expression analysis of testicular DLBCL: ABC or GCB subtype?

(Submitter supplied) Diffuse large B cell lymphomas (DLBCL) constitute a heterogeneous group of lymphomas in which germinal center B cell-like and activated B cell-like subtypes can be discerned based on pathology, clinical presentation and gene expression patterns. Testicular DLBCL form an immune-privileged site-related subgroup of DLBCL with an unfavorable prognosis. We used cDNA microarray analysis, immunohistochemistry for CD10, Bcl6 and MUM1, and somatic hypermutation analysis of the immunoglobulin heavy chain gene rearrangements to determine the subtype of primary testicular DLBCL. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS2219
Platform:
GPL3408
36 Samples
Download data: IMAGENE, TXT
Series
Accession:
GSE4296
ID:
200004296
2.
Full record GDS2219

Testicular diffuse large B cell lymphoma: various subtypes

Analysis of primary testicular diffuse large B cell lymphomas (DLBCLs) and nodal DLBCLs. DLBCLs are classified as germinal center B cell-like (GCB), activated B cell-like, or undetermined. GCB is associated with a favorable prognosis. Results provide insight into the nature of testicular DLBCL.
Organism:
Homo sapiens
Type:
Expression profiling by array, log2 ratio, 4 disease state, 2 tissue sets
Platform:
GPL3408
Series:
GSE4296
36 Samples
Download data: IMAGENE
DataSet
Accession:
GDS2219
ID:
2219
3.

Gene expression analysis of immune privileged site-associated DLBCL: The effect of HLA class II downregulation

(Submitter supplied) Loss of human leukocyte antigen (HLA) expression on tumor cells is frequent in diffuse large B cell lymphoma (DLBCL) arising in immune-privileged sites such as the testis and central nervous system and is associated with small homozygous deletions of HLA-DQ/DR and larger hemizygous deletions of the major histocompatibility complex (MHC) region. To better understand the significance of downregulation of HLA class II expression in relation to the homozygous and hemizygous deletions, we analyzed global gene expression patterns in a series of 26 testicular diffuse large B-cell lymphomas (DLBCL) after characterization of these deletions. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS1960
Platform:
GPL3408
36 Samples
Download data: IMAGENE, TXT
Series
Accession:
GSE4157
ID:
200004157
4.
Full record GDS1960

Testicular diffuse large B cell lymphoma

Analysis of testicular diffuse large B cell lymphoma (DLBCL) tissues with small homozygous HLA-DQ/HLA-DR deletions, larger hemizygous MHC complex deletions, or without deletions. Results provide insight into the significance of the downregulation of HLA class II expression in testicular DLBCL.
Organism:
Homo sapiens
Type:
Expression profiling by array, log2 ratio, 2 disease state, 3 other sets
Platform:
GPL3408
Series:
GSE4157
36 Samples
Download data: IMAGENE
DataSet
Accession:
GDS1960
ID:
1960
5.

NKI/CMF Human 18k cDNA spotted microarray

(Submitter supplied) Spotted cDNA microarray containing 19200 spots: 768 control/empty spots and 18432 cDNA clones, selected from the Research Genetics Human Sequence Verified library. Clones were selected based on the availability of annotation data. Protocol: See CMF website: http://microarray.nki.nl/download/protocols_o.html
Organism:
Homo sapiens
2 DataSets
3 Series
114 Samples
Download data
Platform
Accession:
GPL3408
ID:
100003408
6.

14T

Organism:
Homo sapiens
Source name:
Testicular DLBCL 14T (channel 1) Reference tonsil mix (channel 2)
Platform:
GPL3408
Series:
GSE4157 GSE4296
Datasets:
GDS1960 GDS2219
Download data: IMAGENE
Sample
Accession:
GSM94804
ID:
300094804
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db=gds|term=GSM94804[Accession]|query=1|qty=2|blobid=MCID_61e6ff08a5539e33fe0ab224|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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