GEO DataSets

(Submitter supplied) Radial progenitors deficient in both Mek1 and Mek2 fail to transition to the gliogenic mode in late embryogenesis, and astrocyte and oligodendroglial precursors fail to appear. In exploring mechanisms, we found the Ets transcription family member Etv5/Erm is strongly regulated by MEK. Our microarray assay showed that Erm is specifically downregulated in Mek mutant brain.

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS5449

Platform:

GPL6246

4 Samples

Download data: CEL, CHP

Analysis of brain dorsal cortices of E18.5 embryos deleted for Mek1 and Mek2, dual specificity kinases. Mek1 and Mek2 are components of the RAF/MEK/ERK singaling pathway. Results provide insight into the role of Mek1 and Mek2 in gliogenesis.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:

GPL6246

Series:

GSE40675

4 Samples

Download data: CEL, CHP

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site

Organism:

Mus musculus

143 DataSets

2496 Series

28 Related Platforms

30138 Samples

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