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Items: 1 to 20 of 382

1.

Tick Adiponectin Receptor-Mediated Phospholipid Metabolism Contributes to Borrelia burgdorferi Colonization

(Submitter supplied) Tick gut global gene expression change after silencing adiponectin receptor
Organism:
Ixodes scapularis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL29893
12 Samples
Download data: TXT
Series
Accession:
GSE169293
ID:
200169293
2.

Antiviral RNA interference in disease vector (Asian longhorned) ticks

(Submitter supplied) Tick-borne diseases (TBDs) are the most common illnesses transmitted by ticks, and the annual number of reported TBD cases continues to increase. The Asian longhorned tick, a vector associated with at least 30 human pathogens, is native to eastern Asia and recently reached the USA as an emerging disease threat. Newly identified tick-transmitted pathogens continue to be reported, raising concerns about how TBDs occur. more...
Organism:
Haemaphysalis longicornis
Type:
Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL25900 GPL29237
15 Samples
Download data: TXT
Series
Accession:
GSE159277
ID:
200159277
3.

Transcriptome profile of microRNAs associated with cold tolerance in Dermacentor silvarum ticks

(Submitter supplied) We identified and functionally explored D. silvarum miRNAs involved in cold response to gain further understanding of the molecular regulatory mechanisms underlying the cold stress in ticks. The microRNA libraries of D. silvarum were established via high-throughput sequencing after exposure to different cold treatments. A total of 147 miRNAs, including 44 known miRNAs and 103 new miRNAs, were identified.
Organism:
Dermacentor silvarum
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL30665
15 Samples
Download data: FA, XLS
Series
Accession:
GSE184617
ID:
200184617
4.

RNA-dependent RNA polymerases in the black-legged tick produce Argonaute-dependent small RNAs and regulate genes

(Submitter supplied) Small regulatory RNAs (sRNAs) are involved in anti-viral defense and gene regulation. Although RNA-dependent RNA Polymerases (RdRPs) play essential roles in sRNA biogenesis in nematodes, plants and fungi, their involvement in other animals remains controversial. We identify abundant classes of ~22nt sRNAs that require specific combinations of RdRPs and sRNA effector proteins (Argonautes or AGOs) expressed in the tick ISE6 cell line. more...
Organism:
Ixodes scapularis
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL30611 GPL18496
25 Samples
Download data: XLSX
Series
Accession:
GSE183810
ID:
200183810
5.

Transcriptome profile of Haemaphysalis longicornis (Acari: Ixodidae) exposed to C. citratus essential oil and citronellal

(Submitter supplied) Many genes responsive to C. citratus oil and citronellal were stress-related and they include genes associated with adrenergic signalling/calcium channels, cGMP-PKG signaling, apoptosis, focal adhesion, ECM-receptor interaction, ubiquitin mediated proteolysis, mTOR signalling pathway, and longevity regulating pathway.
Organism:
Haemaphysalis longicornis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25900
21 Samples
Download data: FASTA, TXT
Series
Accession:
GSE176275
ID:
200176275
6.

Lizard feeding enhances Ixodes pacificus vector competence

(Submitter supplied) Ixodes pacificus, the vector of Borrelia burgdorferi (Bb) on the west coast, feeds on a variety of hosts including rodents, birds, and lizards. While rodents are reservoirs for Bb and can infect juvenile ticks, lizards are Bb-refractory. Despite the range of bloodmeals for I. pacificus, it is undetermined how larval host bloodmeal identity may affect future nymphal vector competence. Here, we conducted a transcriptome analysis on I. more...
Organism:
Ixodes pacificus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL30030
18 Samples
Download data: GTF, TXT
Series
Accession:
GSE173109
ID:
200173109
7.

Diverse CGG binding proteins across eukaryotes produced by independent domestications of hAT transposons

(Submitter supplied) The human transcription factor (TF) CGGBP1 (“CGG Binding Protein”) is conserved only in amniotes, and is believed to derive from the zf-BED and Hermes transposase DNA-binding domains (DBDs) of a hAT DNA transposon. Here, we examine the DNA binding preferences of a wide variety of metazoan CGGBP1-like TFs with this bipartite domain using PBM experiments. The derived motifs are available at ...
Organism:
Acyrthosiphon pisum; Salmo salar; Fundulus heteroclitus; Sparus aurata; Chrysemys picta; Austrofundulus limnaeus; Anabas testudineus; Amphiprion percula; Salarias fasciatus; Aedes aegypti; Culex quinquefasciatus; Latimeria chalumnae; Cyprinus carpio; synthetic construct; Hucho hucho; Amphiprion ocellaris; Labeo rohita; Mola mola; Sphaeramia orbicularis; Anabarilius grahami; Petromyzon marinus; Acipenser ruthenus; Gallus gallus; Erpetoichthys calabaricus; Rhizophagus irregularis; Paramormyrops kingsleyae; Locusta migratoria; Crocodylus porosus; Homo sapiens; Rhodnius prolixus; Rhipicephalus appendiculatus; Kryptolebias marmoratus; Nematostella vectensis; Acanthochromis polyacanthus; Hippocampus comes; Hofstenia miamia
Type:
Other
Platform:
GPL11260
258 Samples
Download data: TXT
Series
Accession:
GSE157085
ID:
200157085
8.

Dermacentor marginatus female adults transcriptome

(Submitter supplied) The Ixodidea tick Dermacentor marginatus is a vector of many pathogens wide spread in Eurasia. Study of gene targets of the tick species provides insight to find novel tick protective antigen for drug development and vaccine targets. To obtain a broader picture of gene sequences and changes in expression level, we aimed to characterize the whole body transcriptome in D. marginatus adult female after engorgement and long-term starvation using RNA-seq. more...
Organism:
Dermacentor marginatus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL28620
9 Samples
Download data: FASTA, TXT
Series
Accession:
GSE151667
ID:
200151667
9.

A microRNA profile of saliva and role of miR-375 in Haemaphysalis longicornis (Ixodida: Ixodidae)

(Submitter supplied) Tick saliva contains many bioactive molecules that are involved in attachment to the host, blood feeding and transmission of pathogens. MicroRNAs (miRNAs) are a class of short non-coding RNAs with a length of 19-24 nucleotides. They act as regulators of gene expression by binding to their target mRNA at the post-transcriptional level and control a variety of cellular functions, including regulation of growth, metabolism, and development. more...
Organism:
Haemaphysalis longicornis
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL25900
1 Sample
Download data: TXT, XLSX
Series
Accession:
GSE123407
ID:
200123407
10.

Expression data from engorged Haemaphysalis flava ticks (ET) salivary gland and semi-engorged Haemaphysalis flava ticks (SET) salivary gland (SGs)

(Submitter supplied) To characterize the differentially expressed genes between engorged ticks and semi-engorged ticks
Organism:
Haemaphysalis flava
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19942
2 Samples
Download data: FA, TXT
Series
Accession:
GSE67247
ID:
200067247
11.

Tick-borne Pathogens Induce Differential Expression of Genes Promoting Cell Survival and Host Resistence in Ixodes ricinus Cells

(Submitter supplied) There has been an emergence and expansion of tick-borne diseases in Europe, Asia and North America in recent years, including Lyme disease, tick-borne encephalitis, and human anaplasmosis. The primary tick vectors implicated are hard ticks of the Ixodes genera. Although much is known about the host response to these bacterial and viral pathogens, there is limited knowledge of the cellular responses to infection within the tick vector. more...
Organism:
Ixodes ricinus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21340
6 Samples
Download data: FPKM_TRACKING
Series
Accession:
GSE85300
ID:
200085300
12.

Tissue-specific signatures in the transcriptional response to Anaplasma phagocytophilum infection of Ixodes scapularis and Ixodes ricinus tick cell lines

(Submitter supplied) We report differential gene expression with tissue-specific signatures in tick cell lines infected with Anaplasma phagocytophilum - transcriptional response to infection of I. scapularis ISE6 cells resembled that of tick hemocytes while the response in I. ricinus IRE/CTVM20 cells resembles that of tick midguts.
Organism:
Ixodes ricinus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21340
4 Samples
Download data: FPKM_TRACKING
Series
Accession:
GSE76906
ID:
200076906
13.

Effect of Anaplasma phagocytophilum infection on the micro RNA profile of Ixodes scapularis tick cells

(Submitter supplied) Ticks are blood feeding arthropod ectoparasites that transmit pathogens, which cause diseases in humans and animals worldwide. In the past ten decades, the continuous human exploitation of environmental resources and the increase in human outdoor activities has promoted contact with arthropod vectors normally present in the wild, resulting in increased transmission of vector-borne pathogens. In addition, vector populations are expanding in response to climate change and human interventions that impact reservoir host movement and human exposure to infected vectors. more...
Organism:
Ixodes scapularis
Type:
Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platform:
GPL21603
4 Samples
Download data: GTF
Series
Accession:
GSE79324
ID:
200079324
14.

Integrated metabolomics, transcriptomics and proteomics identifies metabolic pathways affected by Anaplasma phagocytophilum infection in tick cells

(Submitter supplied) Anaplasma phagocytophilum is an emerging zoonotic pathogen that causes human granulocytic anaplasmosis. These intracellular bacteria establish infection by affecting cell function in both the vertebrate host and the tick vector, Ixodes scapularis. Previous studies have characterized the tick transcriptome and proteome in response to A. phagocytophilum infection. However, in the post-genomic era, the integration of omics datasets through a systems biology approach allows network-based analyses to describe the complexity and functionality of biological systems such as host-pathogen interactions and the discovery of new targets for prevention and control of infectious diseases. more...
Organism:
Ixodes scapularis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18496
4 Samples
Download data: GTF
Series
Accession:
GSE68881
ID:
200068881
15.

Expression data from fully engorged Haemaphysalis flava ticks (FE) midgut and partially engorged Haemaphysalis flava ticks (PE) midgut (MGs)

(Submitter supplied) To characterize the differentially expressed genes between fully engorged ticks and partially engorged ticks
Organism:
Haemaphysalis flava
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19942
2 Samples
Download data: FA, TXT
Series
Accession:
GSE69721
ID:
200069721
16.

High throughput sequencing of B.henselae infected and non-infected I. ricinus salivary glands

(Submitter supplied) In order to select genes that are differentially expressed in salivary glands during Ixodes ricinus infection by Bartonella henselae we compare the transcriptome of infected and non-infected salivary glands
Organism:
Ixodes ricinus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL18567 GPL18566
3 Samples
Download data: TSV, TXT
Series
Accession:
GSE56746
ID:
200056746
17.

Comparative microarray analysis of midgut tissues from feeding Rhipicephalus microplus and Rhipicephalus decoloratus adult females

(Submitter supplied) Transcriptional profiling of midgut tissues isolated from Rhipicephalus microplus and Rhipicephalus decoloratus females at day 20 post infestation. This enabled the identification of transcripts that are species-specific or shared between the two tick species tested.
Organism:
Rhipicephalus microplus; Rhipicephalus decoloratus
Type:
Expression profiling by array
Platform:
GPL15231
4 Samples
Download data: GPR, TXT
Series
Accession:
GSE55826
ID:
200055826
18.

Transcriptome analysis of the immature lifestages in feeding Rhipicephalus microplus cattle ticks

(Submitter supplied) Transcriptional profiling of whole nymphs and larvae from Rhipicephalus microplus at day 4 and 7 post infestation, respectively. This enabled the identification of transcripts that are stage-specific or shared among the stages tested.
Organism:
Rhipicephalus microplus
Type:
Expression profiling by array
Platform:
GPL15231
8 Samples
Download data: GPR, TXT
Series
Accession:
GSE37728
ID:
200037728
19.

Comparison of Transcriptome Profiles of Human Ehrlichiosis Agents

(Submitter supplied) This study is to determine and compare the transcriptomes in two eukaryotic hosts (mammalian host - DH82 canine cell line and tick vector - ISE6 Ixodes scapularis cell line) of eight Ehrlichia chaffeensis strains in three divergent genetic groups, including Arkansas, Heartland, Jax, Liberty, Osceola, St. Vincent, Wakulla, and West Paces, and one Ehrlichia sp. HF strain.
Organism:
Ehrlichia sp. HF; Ixodes scapularis; Canis lupus familiaris; Ehrlichia chaffeensis str. Arkansas; Ehrlichia chaffeensis str. Jax; Ehrlichia chaffeensis str. Liberty; Ehrlichia chaffeensis str. Wakulla; Ehrlichia chaffeensis str. Heartland; Ehrlichia chaffeensis str. Osceola; Ehrlichia chaffeensis str. Saint Vincent; Ehrlichia chaffeensis str. West Paces
Type:
Expression profiling by high throughput sequencing
11 related Platforms
120 Samples
Download data: TXT
Series
Accession:
GSE56339
ID:
200056339
20.

Gene expression profiling of adult female tissues in feeding Rhipicephalus microplus cattle ticks

(Submitter supplied) Transcriptional profiling of salivary gland, midgut and ovary tissues isolated from Rhipicephalus microplus females at day 20 post infestation. This enabled the identification of transcripts that are tissue-specific or shared among the tissues tested.
Organism:
Rhipicephalus microplus
Type:
Expression profiling by array
Platform:
GPL15231
12 Samples
Download data: GPR, TXT
Series
Accession:
GSE35867
ID:
200035867
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