GEO DataSets

(Submitter supplied) Butterfly wings display a diversity of cell types, including large polyploid scale cells, yet the molecular basis of such diversity is poorly understood. To explore scale cell diversity at a transcriptomic level, we employ single-cell RNA sequencing of ∼5,200 large cells (>6 μm) from 22.5- to 25-h male pupal forewings of the butterfly Bicyclus anynana. Using unsupervised clustering, followed by in situ hybridization, immunofluorescence, and CRISPR-Cas9 editing of candidate genes, we annotate various cell types on the wing. more...

Organism:

Bicyclus anynana

Type:

Expression profiling by high throughput sequencing

Platform:

GPL33708

1 Sample

Download data: RDS

(Submitter supplied) We measued IgG autoantibodies associated with Connective Tissue Diseases (CTDs) and Anti-Cytokine Antibodies (ACA) in SLE and healthy controls who received the BNT162b2 vaccine.

Organism:

Triticum aestivum; Capra hircus; Homo sapiens; Sus scrofa; Escherichia coli; Spodoptera frugiperda; Bos taurus

Type:

Protein profiling by protein array

Platform:

GPL34257

102 Samples

Download data: TXT, XLSX

(Submitter supplied) PRO-seq experiments in multiple organisms. Also, PRO-seq experiment of Nelfb and Nelfe degron mESC in serum/LIF with or without dTAG-13. 

Organism:

Haloferax mediterranei; Dryas iulia; Nematostella vectensis; Escherichia coli; Mus musculus; Perkinsus marinus; Dictyostelium discoideum; Capsaspora owczarzaki; Creolimax fragrantissima; Daphnia pulex; Strongylocentrotus purpuratus; Sphaeroforma arctica

Type:

Other

12 related Platforms

46 Samples

Download data

(Submitter supplied) The objective of this study was to explore the transcriptional basis of the holometabolous development of Danaus plexippus (the monarch butterfly), which we reasoned would lend insight into how complex life cycles evolve.

Organism:

Danaus plexippus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL34095

50 Samples

Download data: TXT

(Submitter supplied) MicroRNAs (miRNAs) are endogenous small noncoding RNAs (18–25 nt) that are involved in many physiological processes including development, cancer, immunity, apoptosis and host-microbe interactions through posttranscriptional regulation of gene expression. In this study, we measured the profile of small RNAs over the developmental transitions of Spodoptera frugiperda from egg to adult. We identified 741 miRNAs, including 493 known and 248 novel miRNAs. more...

Organism:

Spodoptera frugiperda

Type:

Non-coding RNA profiling by high throughput sequencing

Platform:

GPL25030

18 Samples

Download data: XLS

(Submitter supplied) RNA-guided endonucleases form the crux of diverse biological processes and technologies, including adaptive immunity, transposition, and genome editing. Some of these enzymes are components of insertion sequences (IS) in the IS200/IS605 and IS607 transposon families. Both IS families encode a TnpA transposase and TnpB nuclease, an RNA-guided enzyme ancestral to CRISPR-Cas12. In eukaryotes and their viruses, TnpB homologs occur as two distinct types, Fanzor1 and Fanzor2. more...

Organism:

Escherichia coli; Spodoptera frugiperda

Type:

Non-coding RNA profiling by high throughput sequencing

Platforms:

GPL33862 GPL16085

6 Samples

Download data: BW, FASTA

(Submitter supplied) Bioinsecticides and transgenic crops based on the bacterial pathogen Bacillus thuringiensis (Bt) can effectively control diverse agricultural insect pests, nevertheless, insect resistance evolution without causing obvious fitness costs has seriously eroded the sustainable use of these Bt products. Recently, we have discovered that an increased titer of juvenile hormone (JH) favors an insect host (Plutella xylostella) to enhance fitness whilst resisting the Bt pathogen, however, the underlying regulatory mechanisms of the increased JH titer is obscure. more...

Organism:

Plutella xylostella

Type:

Other

Platform:

GPL28843

12 Samples

Download data: TXT

(Submitter supplied) Cruciferous plants produce sulforaphane (SFN), an inhibitor of nuclear histone deacetylases (HDACs). In humans and other mammals, the consumption of SFN alters enzyme activities, DNA-histone binding, and gene expression within minutes. However, the ability of SFN to act as a HDAC inhibitor in nature, disrupting the epigenetic machinery of insects feeding on these plants, has not been explored. Here, we investigate the effect of SFN, as well as the pharmaceutical HDAC inhibitor Trichostatin A (TSA), consumed in the diet in the generalist grazer Spodoptera exigua and in the co-evolved specialist feeder Trichoplusia ni. more...

Organism:

Spodoptera exigua; Trichoplusia ni

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL29211 GPL33468

20 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Ostrinia furnacalis

Type:

Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing

Platform:

GPL32008

15 Samples

Download data: BROADPEAK, BW, TXT

(Submitter supplied) H3K9me3 and H3K27me3 were involved in diapause regulation of O. furnacalis larvae

Organism:

Ostrinia furnacalis

Type:

Methylation profiling by high throughput sequencing

Platform:

GPL32008

6 Samples

Download data: TXT

(Submitter supplied) H3K9me3 and H3K27me3 were involved in diapause regulation of O. furnacalis larvae

Organism:

Ostrinia furnacalis

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL32008

9 Samples

Download data: BROADPEAK, BW

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Bombyx mori

Type:

Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other

Platform:

GPL29210

27 Samples

Download data: BIGWIG, BW, MCOOL

(Submitter supplied) Genome organization in diverse eukaryotes follows conserved principles including the formation of chromosome territories (CT), chromatin compartments, and TADs. Here, we describe the 3D architecture of holocentric chromosomes in the silkworm Bombyx mori. At the genome-wide scale, B. mori chromosomes are highly territorial lacking any visible trans contact pattern. At the chromosomal scale, B. mori chromosomes segregate into three chromatin compartments: an active A and an inactive B as described in other eukaryotes, and a third type, X, with a unique contact pattern. more...

Organism:

Bombyx mori

Type:

Other

Platform:

GPL29210

3 Samples

Download data: MCOOL

(Submitter supplied) Genome organization in diverse eukaryotes follows conserved principles including the formation of chromosome territories (CT), chromatin compartments, and TADs. Here, we describe the 3D architecture of holocentric chromosomes in the silkworm Bombyx mori. At the genome-wide scale, B. mori chromosomes are highly territorial lacking any visible trans contact pattern. At the chromosomal scale, B. mori chromosomes segregate into three chromatin compartments: an active A and an inactive B as described in other eukaryotes, and a third type, X, with a unique contact pattern. more...

Organism:

Bombyx mori

Type:

Other

Platform:

GPL29210

1 Sample

Download data: MCOOL

(Submitter supplied) Genome organization in diverse eukaryotes follows conserved principles including the formation of chromosome territories (CT), chromatin compartments, and TADs. Here, we describe the 3D architecture of holocentric chromosomes in the silkworm Bombyx mori. At the genome-wide scale, B. mori chromosomes are highly territorial lacking any visible trans contact pattern. At the chromosomal scale, B. mori chromosomes segregate into three chromatin compartments: an active A and an inactive B as described in other eukaryotes, and a third type, X, with a unique contact pattern. more...

Organism:

Bombyx mori

Type:

Expression profiling by high throughput sequencing

Platform:

GPL29210

3 Samples

Download data: BW, XLSX

(Submitter supplied) Genome organization in diverse eukaryotes follows conserved principles including the formation of chromosome territories (CT), chromatin compartments, and TADs. Here, we describe the 3D architecture of holocentric chromosomes in the silkworm Bombyx mori. At the genome-wide scale, B. mori chromosomes are highly territorial lacking any visible trans contact pattern. At the chromosomal scale, B. mori chromosomes segregate into three chromatin compartments: an active A and an inactive B as described in other eukaryotes, and a third type, X, with a unique contact pattern. more...

Organism:

Bombyx mori

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL29210

20 Samples

Download data: BIGWIG

(Submitter supplied) Hyperproteinemia is a metabolic disorder characterized by abnormally elevated plasma protein concentrations (PPC) in humans and animals. Here, a genetic silkworm model with high PPC was employed to investigate the effect of elevated PPC on female reproduction. Transcriptomic analysis revealed that high PPC induces downregulation of the ovarian development-related genes and disrupts ovarian sugar metabolism. more...

Organism:

Bombyx mori

Type:

Expression profiling by high throughput sequencing

Platform:

GPL29210

12 Samples

Download data: TXT

(Submitter supplied) The fall armyworm (FAW) Spodoptera frugiperda is one of the most severe economic pests of multiple crops globally. Control of this pest is often achieved using insecticides; however, over time, S. frugiperda has developed resistance to new mode of action compounds, including diamides. Previous studies have indicated diamide resistance is a complex developmental process involving multiple detoxification genes. more...

Organism:

Spodoptera frugiperda

Type:

Non-coding RNA profiling by high throughput sequencing

Platform:

GPL33457

6 Samples

Download data: XLSX

(Submitter supplied) The silk gland development has a greater impact on silk yields in silkworms. Silk glands from three pure silkworm strains (A798, A306, and XH) with different silk gland weight phenotypes were compared using transcriptome, proteomics, and WGCNA. Five genes (BGIBMGA002524, BGIBMGA002629, BGIBMGA005659, BGIBMGA005711, and BGIBMGA010889) may be strongly associated with the growth of silk glands to be confirmed. more...

Organism:

Bombyx mori

Type:

Expression profiling by high throughput sequencing

Platform:

GPL23127

9 Samples

Download data: TXT

(Submitter supplied) Temperature has fundamental influences on fitness and distribution of insects. There have been very few studies on effects of mild cold conditions on insects. We found Plutella xylostella had reduced fitness and females produced few viable eggs when reared at 10°C, a temperature at which they can complete development. Male moths reared at 10°C were not able to fertilize eggs, but the eggs produced by female moths reared at this temperature were viable and could be fertilisied by males moths reared at a warmer temperature (25°C). more...

Organism:

Plutella xylostella

Type:

Expression profiling by high throughput sequencing

Platform:

GPL28843

12 Samples

Download data: TXT