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Items: 1 to 20 of 924

1.

Unistrand piRNA clusters are an evolutionarily conserved mechanism to suppress endogenous retroviruses across the Drosophila genus

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Drosophila mojavensis; Drosophila persimilis; Drosophila azteca; Drosophila takahashii; Drosophila erecta; Drosophila pseudoobscura; Drosophila ficusphila; Drosophila melanogaster; Drosophila simulans; Drosophila yakuba; Drosophila suzukii; Drosophila ananassae; Drosophila subobscura; Drosophila virilis; Drosophila biarmipes
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
20 related Platforms
118 Samples
Download data: BW, NARROWPEAK
Series
Accession:
GSE225889
ID:
200225889
2.

Unistrand piRNA clusters are an evolutionarily conserved mechanism to suppress endogenous retroviruses across the Drosophila genus [small RNA-Seq]

(Submitter supplied) The PIWI-interacting RNA (piRNA) pathway plays a crucial role in preventing endogenous genomic parasites, transposable elements (TEs), from damaging the genetic material of animal gonadal cells. Specific regions in the genome, called piRNA clusters, define each species’ piRNA repertoire and therefore its capacity to recognize and silence transposons. In the somatic cells of the Drosophila melanogaster ovary, the flamenco (flam) unistrand cluster is the main source of piRNAs and primarily regulates Gypsy family TEs that are able to form virus-like particles and infect neighbouring germ cells. more...
Organism:
Drosophila persimilis; Drosophila takahashii; Drosophila bifasciata; Drosophila melanogaster; Drosophila pseudoobscura; Drosophila subobscura; Drosophila ficusphila; Drosophila ananassae; Drosophila erecta; Drosophila mojavensis; Drosophila virilis; Drosophila azteca; Drosophila biarmipes; Drosophila simulans; Drosophila yakuba; Drosophila suzukii
Type:
Non-coding RNA profiling by high throughput sequencing
15 related Platforms
65 Samples
Download data: BW
Series
Accession:
GSE225888
ID:
200225888
3.

Unistrand piRNA clusters are an evolutionarily conserved mechanism to suppress endogenous retroviruses across the Drosophila genus [RNA-Seq]

(Submitter supplied) The PIWI-interacting RNA (piRNA) pathway plays a crucial role in preventing endogenous genomic parasites, transposable elements (TEs), from damaging the genetic material of animal gonadal cells. Specific regions in the genome, called piRNA clusters, define each species’ piRNA repertoire and therefore its capacity to recognize and silence transposons. In the somatic cells of the Drosophila melanogaster ovary, the flamenco (flam) unistrand cluster is the main source of piRNAs and primarily regulates Gypsy family TEs that are able to form virus-like particles and infect neighbouring germ cells. more...
Organism:
Drosophila ananassae; Drosophila persimilis; Drosophila takahashii; Drosophila bifasciata; Drosophila melanogaster; Drosophila pseudoobscura; Drosophila subobscura; Drosophila ficusphila; Drosophila simulans; Drosophila yakuba; Drosophila suzukii; Drosophila erecta; Drosophila mojavensis; Drosophila virilis; Drosophila azteca; Drosophila biarmipes
Type:
Expression profiling by high throughput sequencing
10 related Platforms
35 Samples
Download data: BW
Series
Accession:
GSE225887
ID:
200225887
4.

Mechanistic divergence of piRNA biogenesis in Drosophila

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Drosophila bifasciata; Drosophila eugracilis; Drosophila melanogaster; Drosophila mojavensis; Drosophila pseudoobscura
Type:
Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
5 related Platforms
27 Samples
Download data: BED, TXT
Series
Accession:
GSE213383
ID:
200213383
5.

Mechanistic divergence of piRNA biogenesis in Drosophila [ncRNA-seq]

(Submitter supplied) Organisms require mechanisms to distinguish self and non-self RNA. This distinction is crucial to initiate the biogenesis of piRNAs. In Drosophila ovaries, PIWI-guided slicing and the recognition of piRNA precursor transcripts by the DEAD-box RNA helicase Yb are the two known mechanisms to initiate biogenesis in the germline and the soma, respectively. Both, the PIWI proteins and Yb are highly conserved across most Drosophila species and are thought to be essential to the piRNA pathway and for silencing TEs. more...
Organism:
Drosophila eugracilis; Drosophila bifasciata; Drosophila melanogaster; Drosophila pseudoobscura; Drosophila mojavensis
Type:
Non-coding RNA profiling by high throughput sequencing
5 related Platforms
17 Samples
Download data: BED, TXT
Series
Accession:
GSE213369
ID:
200213369
6.

Evolutionary changes in cis regulation are associated with altered chromatin activity and gene expression levels in the Drosophila eye development (RNA-Seq)

(Submitter supplied) Expression profiling by high-throughput sequencing (RNA-seq) across eight WT Drosophila species - D. melanogaster, D. simulans, D. yakuba, D. ananassae, D. pseudoobscura, D. willistoni, D. mojavensis and D. virilis - and three tissues, namely, brain, eye-antennal and imaginal discs, at the stage of third instar larvae.
Organism:
Drosophila melanogaster; Drosophila pseudoobscura; Drosophila ananassae; Drosophila mojavensis; Drosophila virilis; Drosophila willistoni; Drosophila simulans; Drosophila yakuba
Type:
Expression profiling by high throughput sequencing
8 related Platforms
27 Samples
Download data: TXT
Series
Accession:
GSE59707
ID:
200059707
7.

Evolution of maternal and zygotic mRNA complements in the early Drosophila embryo

(Submitter supplied) The earliest stage of animal development is controlled by maternally deposited mRNA transcripts and proteins. Once the zygote is able to transcribe its own genome, maternal transcripts are degraded, in a tightly regulated process known as the maternal to zygotic transition (MZT). While this process has been well-studied within model species, we have little knowledge of how the pools of maternal and zygotic transcripts evolve. more...
Organism:
Drosophila ananassae; Drosophila erecta; Drosophila miranda; Drosophila sechellia; Drosophila simulans; Drosophila virilis; Drosophila melanogaster; Drosophila yakuba; Drosophila mauritiana; Drosophila mojavensis; Drosophila pseudoobscura; Drosophila willistoni; Drosophila persimilis; Drosophila santomea
Type:
Expression profiling by high throughput sequencing; Third-party reanalysis
14 related Platforms
119 Samples
Download data: TXT
Series
Accession:
GSE112858
ID:
200112858
8.

The transcription factor Grainyhead primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Drosophila melanogaster; Drosophila pseudoobscura; Drosophila persimilis; Homo sapiens; Drosophila ananassae; Drosophila erecta; Drosophila mojavensis; Drosophila virilis; Drosophila willistoni; Drosophila sechellia; Drosophila simulans; Drosophila yakuba
Type:
Genome binding/occupancy profiling by high throughput sequencing
15 related Platforms
175 Samples
Download data: BW
Series
Accession:
GSE102441
ID:
200102441
9.

The transcription factor Grainyhead primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes [evolutionary study]

(Submitter supplied) Transcriptional enhancers function as docking platforms for combinations of transcription factors to control gene expression. How enhancer sequences determine nucleosome occupancy, transcription factor recruitment, and transcriptional activation in vivo remains unclear. Using ATAC-seq across a panel of Drosophila inbred strains we found that SNPs affecting Grainyhead binding sites causally determine the accessibility of epithelial enhancers. more...
Organism:
Drosophila melanogaster; Drosophila pseudoobscura; Drosophila yakuba; Drosophila ananassae; Drosophila sechellia; Drosophila simulans; Drosophila erecta; Drosophila mojavensis; Drosophila virilis; Drosophila willistoni; Drosophila persimilis
Type:
Genome binding/occupancy profiling by high throughput sequencing
12 related Platforms
24 Samples
Download data: BW
Series
Accession:
GSE102439
ID:
200102439
10.

Small RNAs from 11 Drosophila species

(Submitter supplied) Annotation of small RNAs from 11 Drosophila species for the purpose of non-coding RNA annotation and comparative genomics assessment.
Organism:
Drosophila pseudoobscura; Drosophila mojavensis; Drosophila persimilis; Drosophila willistoni; Drosophila ananassae; Drosophila erecta; Drosophila virilis; Drosophila grimshawi; Drosophila sechellia; Drosophila simulans; Drosophila yakuba
Type:
Non-coding RNA profiling by high throughput sequencing
22 related Platforms
56 Samples
Download data: TXT
Series
Accession:
GSE98013
ID:
200098013
11.

TRANSCRIPTIONAL RESPONSES OF ECOLOGICALLY DIVERSE DROSOPHILA SPECIES TO LARVAL DIETS DIFFERING IN RELATIVE SUGAR AND PROTEIN RATIOS

(Submitter supplied) We utilized three ecologically diverse Drosophila species to explore the influence of ecological adaptation on transcriptomic responses to isocaloric diets differing in their relative proportions of protein to sugar. Drosophila melanogaster, a cosmopolitan species that breeds in decaying fruit, exemplifies individuals long exposed to a Western diet higher in sugar, while the natural diet of the cactophilic D. more...
Organism:
Drosophila arizonae; Drosophila melanogaster; Drosophila mojavensis
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL13304 GPL13311 GPL23809
18 Samples
Download data: DIFF, TXT
Series
Accession:
GSE101664
ID:
200101664
12.

RNA-seq of sexed adult tissues/body parts from eight Drosophila species

(Submitter supplied) This data set contains polyA+ transcriptional profiling of sexed adult tissues/body parts and whole adults of eight Drosophila species: Drosophila melanogaster (FBsp00000001) from two strains [w1118 (FBst0005905) and Oregon-R (FBst0025211)], Drosophila yakuba (FBsp00000254), Drosophila ananassae (FBsp00000052), Drosophila pseudoobscura (FBsp00000201), Drosophila persimilis (FBsp00000188), Drosophila willistoni (FBsp00000253), Drosophila mojavensis (FBsp00000160), and Drosophila virilis (FBsp00000251). more...
Organism:
Drosophila ananassae; Drosophila persimilis; Drosophila melanogaster; Drosophila pseudoobscura; Drosophila mojavensis; Drosophila virilis; Drosophila willistoni; Drosophila yakuba; synthetic construct
Type:
Expression profiling by high throughput sequencing
12 related Platforms
856 Samples
Download data: PDF, TXT
Series
Accession:
GSE99574
ID:
200099574
13.

Geographical and host plant influences on transcriptional variation in Drosophila mojavensis: mapping gene expression differences in both sexes

(Submitter supplied) Geographical and host plant influences on transcriptional variation in Drosophila mojavensis: mapping gene expression differences in both sexes. (1. Punta Onah:PO07; 2. Organ Pipe National Monument:OPNM08; 3. Punta Prieta:PP08; & 4. San Quintin:SQ08). The experiment was designed to investigate effects of host plant (diet), mating status (mated:M or nonmated:V) and sex (male:male or Female:F) on transcriptome.
Organism:
Drosophila mojavensis
Type:
Expression profiling by array
Platform:
GPL16433
127 Samples
Download data: PAIR
Series
Accession:
GSE78852
ID:
200078852
14.

Functional genomic responses to temperature variation in adult Drosophila mojavensis

(Submitter supplied) Investigation of whole genome transcription expression level changes in Drosophila mojavensis wild-type populations (1 Punta Onah: PO, 2 Organ Pipe National Monument: OPNM, 3 Punta Prieta:PP, and 4 San Quintin: SQ). The experiment was designed to investigate functional genomic responses to temperature variation (15, 25, and 35 °C) in adult Drosophila mojavensis wild populations. For each treatment 1-5 replicates were used (R1, R2, R3, R4 & R5). more...
Organism:
Drosophila mojavensis
Type:
Expression profiling by array
Platform:
GPL16433
97 Samples
Download data: PAIR
Series
Accession:
GSE72169
ID:
200072169
15.

Preadult life history variation determines adult transcriptome expression

(Submitter supplied) Investigation of whole genome transcription expression level changes in Drosophila mojavensis wild-type populations (Las Bocas:LB and Punta Prieta:PP). The experiment was designed to investigate preadult life history affects over adult transcriptome expression.
Organism:
Drosophila mojavensis
Type:
Expression profiling by array
Platform:
GPL16433
137 Samples
Download data: PAIR
Series
Accession:
GSE72231
ID:
200072231
16.

Transcriptional differentiation across the four cactus host races of Drosophila mojavensis

(Submitter supplied) Local adaptation can play a fundamental role in the isolation of populations. While less well-studied than differentiation in sequence variation, changes in transcriptional variation during speciation also are fundamental to the evolutionary process. Drosophila mojavensis offers an unprecedented opportunity to examine the role of transcriptional differentiation in local adaptation. Drosophila mojavensis is a cactophilic fly composed of four ecologically distinct subspecies that inhabit the deserts of western North America. more...
Organism:
Drosophila mojavensis mojavensis; Drosophila mojavensis sonorensis; Drosophila mojavensis; Drosophila mojavensis wrigleyi
Type:
Expression profiling by array
Platform:
GPL13212
44 Samples
Download data: TXT
Series
Accession:
GSE41155
ID:
200041155
17.

Deciphering life history transcriptomics in different environments

(Submitter supplied) Investigation of whole genome transcription expression level changes in Drosophila mojavensis wild-type populations (Las Bocas:LB and Punta Prieta:PP). The experiment was designed to investigate life history transcriptomics in different environments.
Organism:
Drosophila mojavensis
Type:
Expression profiling by array
Platform:
GPL16433
172 Samples
Download data: PAIR
Series
Accession:
GSE54510
ID:
200054510
18.

Comparative Validation of the D. melanogaster Encyclopedia of DNA Elements Transcript Models

(Submitter supplied) The model organism Encyclopedia of DNA Elements project (modENCODE) has produced a comprehensive annotation of D. melanogaster transcript models based on an enormous amount of high-throughput experimental data. However, some transcribed elements may not be functional, and technical artifacts may lead to erroneous inference of transcription. Inter-species comparison provides confidence to predicted annotation, since transcriptional activity that has been evolutionarily conserved is likely to have an advantageous function. more...
Organism:
Drosophila mojavensis; Drosophila yakuba; Drosophila ananassae; Drosophila simulans; Drosophila virilis; Drosophila elegans; Drosophila biarmipes; Drosophila eugracilis; Drosophila takahashii; Drosophila ficusphila; Drosophila kikkawai; Drosophila bipectinata; Drosophila rhopaloa; Drosophila melanogaster; Drosophila pseudoobscura
Type:
Expression profiling by high throughput sequencing
34 related Platforms
93 Samples
Download data: BAM, BED, RPKM, TXT
Series
Accession:
GSE44612
ID:
200044612
19.

Functional genomic and phenotypic responses to desiccation in natural populations of a desert drosophilid.

(Submitter supplied) Investigation of whole genome transcription expression level changes in Drosophila mojavensis wild-type populations (1. Punta Onah:PO; 2. Organ Pipe National Manument:OPNM; 3. Punta Prieta:PP; & 4. San Quintin:SQ). The experiment was designed to investigate effects of desiccation exposure (0, 9 & 18 hr) and host plant (diet) on transcriptome.
Organism:
Drosophila mojavensis
Type:
Expression profiling by array
Platform:
GPL16433
95 Samples
Download data: PAIR, TXT
Series
Accession:
GSE43220
ID:
200043220
20.

Population transcriptomics of cactus host shifts in Drosophila mojavensis

(Submitter supplied) In the presence of environmental change, natural selection can shape the transcriptome. Under a scenario of environmental change, genotypes that are better able to modulate gene expression to maximize fitness will tend to be favored. Therefore, it is important to examine gene expression at the population level in order to distinguish random or neutral gene expression variation from the pattern produced by natural selection. more...
Organism:
Drosophila mojavensis
Type:
Expression profiling by array
Platform:
GPL8596
36 Samples
Download data: PAIR
Series
Accession:
GSE35937
ID:
200035937
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