txid9360[Organism:exp] - GEO DataSets

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Select item 2002162231.

Promoting in vivo Adult Liver Organ Growth with Bacteria without Fibrosis and Tumorigenesis

(Submitter supplied) Strategies that promote functional organ growth with minimal adverse effects are the ultimate goal of regenerative medicine but no single approach is currently available for organ level repair. Here, using an evolutionary adapted in vivo infection model - Mycobacterium leprae, with host cell reprogramming ability and its natural animal host, the nine-banded armadillo (Dasypus novemcinctus) that harbor bacteria in the highly regenerative liver - we present an in vivo model for promoting adult liver growth at organ level without adverse effects. more...

Organism:: Dasypus novemcinctus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL32766
12 Samples

Download data: TSV

Series

Accession:: GSE216223

ID:: 200216223

PubMed Full text in PMC Similar studies

Select item 2001205102.

RNA-seq data of nine-banded armadillo uterus

(Submitter supplied) RNA-seq data of non-pregnant and peri-implantation stage nine-banded armadillo (Dasypus novemcinctus) uterus

Organism:: Dasypus novemcinctus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL22344
2 Samples

Download data: TXT

Series

Accession:: GSE120510

ID:: 200120510

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001060773.

A quantitative model for characterizing the evolutionary history of mammalian gene expression

(Submitter supplied) Characterizing the evolutionary history of a gene’s expression profile is a critical component for understanding the relationship between genotype, expression, and phenotype. However, it is not well-established how best to distinguish the different evolutionary forces acting on gene expression. Here, we use RNA-seq across 7 tissues from 17 mammalian species to show that expression evolution across mammals is accurately modeled by the Ornstein-Uhlenbeck (OU) process. more...

Organism:: Dasypus novemcinctus; Canis lupus familiaris; Mustela putorius furo; Monodelphis domestica; Oryctolagus cuniculus

Type:: Expression profiling by high throughput sequencing

5 related Platforms
33 Samples

Download data: TXT

Series

Accession:: GSE106077

ID:: 200106077

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000858154.

Evolution of Gene Expression in the Uterine Cervix related to Steroid Signaling: Conserved features in the regulation of cervical remodeling.

(Submitter supplied) The uterine cervix is the boundary structure between the uterus and the vagina and is a key component of the female reproductive tract for the maintenance of pregnancy and timing of parturition. Here we report on a comparative transcriptomic study of the cervix of four placental mammal species, mouse, guinea pig, rabbit and the basal eutherian mammal, armadillo, Dasypus novemcinctus, and one marsupial species, Monodelphis domestica. more...

Organism:: Dasypus novemcinctus; Oryctolagus cuniculus; Mus musculus; Monodelphis domestica

Type:: Expression profiling by high throughput sequencing

8 related Platforms
35 Samples

Download data: CSV

Series

Accession:: GSE85815

ID:: 200085815

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000791215.

Expression Profiling of Term Placenta in Viviparous Mammals by RNA-Seq

(Submitter supplied) The placenta is arguably the most anatomically variable organ in mammals. Understanding gene expression patterns among placentas from multiple species can illuminate the molecular basis of placenta function as well as potentially enrich our knowledge of the biology of obstetrical syndromes. We measured the expression profiles of the term placenta of multiple therian mammals using RNA-Seq. We identified multiple genes and transcripts which are differentially expressed across lineages including prolactin, relaxin, and galectins, as well as identifying the non-housekeeping genes which are core to placenta function (such as components of annexin complexes) in all species studied.

Organism:: Ateles fusciceps; Mus musculus; Dasypus novemcinctus; Pan paniscus; Canis lupus familiaris; Monodelphis domestica; Loxodonta africana; Bos taurus

Type:: Expression profiling by high throughput sequencing

8 related Platforms
8 Samples

Download data: FASTA, FPKM_TRACKING

Series

Accession:: GSE79121

ID:: 200079121

SRA Run Selector

Select item 2000577146.

Gene expression profiling in the endometrium of pregnant mammals

(Submitter supplied) A major challenge in biology is to determine how evolutionarily novel characters originate, however, mechanistic explanations for the origin of novelties are almost completely unknown. The evolution of mammalian pregnancy is an excellent system in which to study the origin of novelties because extant mammals preserve major stages in the transition from egg-laying to live-birth. To determine the molecular bases of this transition, we characterized the pregnant/gravid uterine transcriptome from tetrapods, including species in the three major mammalian lineages, and used ancestral transcriptome reconstruction to trace the evolutionary history of uterine gene expression. more...