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Links from BioProject

Items: 4

1.

Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS2746
Platform:
GPL1261
21 Samples
Download data: CEL
Series
Accession:
GSE8000
ID:
200008000
2.

Comparison between gene expression in heart from Lmna H222P homozygous and control mice

(Submitter supplied) The present research is devoted to the identification of gene(s) severely affected by LMNA mutations, leading to striated muscle laminopathies and more specifically the cardiomyopathy. For this purpose, we developped a large-scale gene expression approach on heart and skeletal tissues from Lmna H222P heterozygous Knock-In mouse model. Keywords: disease state modification
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
14 Samples
Download data: CEL
Series
Accession:
GSE6398
ID:
200006398
3.

Comparison between gene expression in heart from Lmna H222P heterozygous and control mice

(Submitter supplied) The present research is devoted to the identification of gene(s) severely affected by LMNA mutations, leading to striated muscle laminopathies and more specifically the cardiomyopathy. For this purpose, we developped a large-scale gene expression approach on heart and skeletal tissues from Lmna H222P heterozygous Knock-In mouse model. Keywords: disease state modification
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
15 Samples
Download data: CEL
Series
Accession:
GSE6397
ID:
200006397
4.
Full record GDS2746

Lmna H222P homozygous and heterozygous mutant models of Emery-Dreifuss muscular dystrophy: hearts

Analysis of hearts of A-type lamin Lmna H222P homo-/heterozygous mutants. LMNA mutations lead to autosomal dominant and recessive Emery-Dreifuss muscular dystrophy which is characterized by dilated cardiomyopathy. Results provide insight into the role of LMNA in the development of cardiomyopathy.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 genotype/variation sets
Platform:
GPL1261
Series:
GSE8000
21 Samples
Download data: CEL
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