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Items: 3

1.

Integral roles for Rev-erb alpha and Rev-erb beta in the circadian clock function

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array
Platforms:
GPL9250 GPL6885
27 Samples
Download data: BEDGRAPH, TXT
Series
Accession:
GSE34020
ID:
200034020
2.

Integral roles for Rev-erb alpha and Rev-erb beta in the circadian clock function [ChIP_seq]

(Submitter supplied) The circadian clock acts at the genomic level to coordinate internal behavioral and physiologic rhythms via the CLOCK-BMAL transcriptional heterodimer. Although the nuclear receptors REV-ERBα and β have been proposed to contribute to clock function, their precise roles and importance remain unresolved. To establish their regulatory potential we generated comparative cistromes of both Rev-erb isoforms, which revealed shared recognition at over ~50% of their total sites and extensive overlap with the master clock regulator Bmal. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL9250
3 Samples
Download data: BEDGRAPH, TXT
Series
Accession:
GSE34019
ID:
200034019
3.

Integral roles for Rev-erb alpha and Rev-erb beta in the circadian clock function [Expression array]

(Submitter supplied) The circadian clock acts at the genomic level to coordinate internal behavioral and physiologic rhythms via the CLOCK-BMAL transcriptional heterodimer. Although the nuclear receptors REV-ERBα and β have been proposed to contribute to clock function, their precise roles and importance remain unresolved. To establish their regulatory potential we generated comparative cistromes of both Rev-erb isoforms, which revealed shared recognition at over ~50% of their total sites and extensive overlap with the master clock regulator Bmal. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
24 Samples
Download data: TXT
Series
Accession:
GSE34018
ID:
200034018
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