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Items: 2

1.

Acquired resistance to lapatinib

(Submitter supplied) These studies are aimed at understanding gene expression chnages in a Her2 positive breast cancer cell line that has developed acquired resistance to lapatinib. Samples include SKBR3 parental and resistant (SKBR3-R) under basal conditions and in response to 0.1 and 1uM lapatinib treatment after 24 hours.
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4979
Platform:
GPL6947
18 Samples
Download data: TXT
Series
Accession:
GSE38376
ID:
200038376
2.
Full record GDS4979

Lapatinib effect on lapatinib-resistant ErbB2-positive cell line: dose response

Analysis of lapatinib-resistant ErbB2-positive cells treated with 0.1 or 1 uM lapatinib. Lapatinib is an EGFR/ErbB2 inhibitor used to treat ErbB2‐positive advanced or metastatic breast cancer. Results provide insight into the mechanisms underlying the development of resistance to lapatinib.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 cell type, 3 dose sets
Platform:
GPL6947
Series:
GSE38376
18 Samples
Download data

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