GEO DataSets for BioProject (Select 185171) - GEO DataSets

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Items: 3

Select item 2000432611.

Fluoxetine resistance in mice is associated with attenuated progression of a stereotyped dentate gyrus gene expression program

(Submitter supplied) Selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine are the most common treatment for major depression. However, approximately 50% of depressed patients fail to achieve an effective treatment response. Understanding how gene expression systems relate to treatment responses may be critical for understanding antidepressant resistance. Transcriptome profiling allows for the simultaneous measurement of expression levels for thousands of genes and the opportunity to utilize this information to determine mechanisms underlying antidepressant treatment responses. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Datasets:: GDS5307 GDS5308
Platform:: GPL1261
38 Samples

Download data: CEL

Series

Accession:: GSE43261

ID:: 200043261

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 53082.

Antidepressant fluoxetine effect on depression model: ventral dentate gyrus

Analysis of ventral dentate gyrus from adults subjected to chronic corticosterone (CORT) to induce depression-like behaviors, followed by combined treatment of CORT and selective serotonin reuptake inhibitor fluoxetine. Results provide insight into the molecular basis of antidepressant resistance.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent, 3 individual sets

Platform:: GPL1261
Series:: GSE43261
19 Samples

Download data: CEL

DataSet

Accession:: GDS5308

ID:: 5308

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 53073.

Antidepressant fluoxetine effect on depression model: dorsal dentate gyrus

Analysis of dorsal dentate gyrus from adults subjected to chronic corticosterone (CORT) to induce depression-like behaviors, followed by combined treatment of CORT and selective serotonin reuptake inhibitor fluoxetine. Results provide insight into the molecular basis of antidepressant resistance.