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Items: 2

1.

Gata-1 Knock Down - Wild Type Megakaryocyte Gene Expression

(Submitter supplied) Hematopoietic progenitor cells were isolated from 13.5 day mouse fetal livers by lineage depletion and expanded for three days. Fetal livers were isolated from both wild type and Gata-1 knock embryos. Gata-1 knock embryos contain a deletion of the Gata-1 promoter sequence that results in undetectable levels of Gata-1 protein specifically in the megakaryocyte lineage. Following progenitor outgrowth megakaryocytes were enriched in a differentiation media for three days and isolated on a discontinuous BSA gradient. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS1245
Platform:
GPL1261
6 Samples
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Series
Accession:
GSE2527
ID:
200002527
2.
Full record GDS1245

GATA-1 knockdown effect on megakaryocytes

Analysis of megakaryocytes lacking the transcription factor GATA-1. GATA-1 is required for the development of megakaryocytes and erythroid cells. Megakaryocytes obtained from 13.5 day C57BL/6 mutant embryos. Results provide insight into the role of GATA-1 in megakaryopoiesis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE2527
6 Samples
Download data

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