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Comprehensive analysis of PPARa-dependent regulation of hepatic lipid metabolism by expression profiling

(Submitter supplied) PPARalpha is a ligand-activated transcription factor involved in the regulation of nutrient metabolism and inflammation. Although much is already known about the function of PPARalpha in hepatic lipid metabolism, many PPARalpha-dependent pathways and genes have yet to be discovered. In order to obtain an overview of PPARalpha-regulated genes relevant to lipid metabolism, and to probe for novel candidate PPARalpha target genes, livers from several animal studies in which PPARalpha was activated and/or disabled were analyzed by Affymetrix GeneChips. more...
Organism:
Homo sapiens; Mus musculus; Rattus norvegicus
Type:
Expression profiling by array
4 related Platforms
47 Samples
Download data: CEL
Series
Accession:
GSE8316
ID:
200008316

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