Sustained L-type Calcium Channel Blockade Alters Gene Regulation in the Adult Mouse Ventricle - - GEO DataSets

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Sustained L-type Calcium Channel Blockade Alters Gene Regulation in the Adult Mouse Ventricle

(Submitter supplied) Objective: L-type calcium channels (LTCC) homeostatically regulate calcium on a beat by beat basis, but also provide Ca that over long time scales may contribute to transcriptional regulation. We previously showed that sustained LTCC blockade (CCB) elicits LTCC remodeling in ventricular cardiac myocytes (CM). Here we hypothesize that sustained CCB has broad effects on the expression of genes involved in calcium handling. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1261
12 Samples

Download data: CEL, CHP

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Accession:: GSE8367

ID:: 200008367

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