U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from BioProject

Transcriptional Profiling of the Megabladder Mouse - A Unique Model of Bladder Dysmorphogenesis

(Submitter supplied) Recent studies in our lab have identified a mutant mouse model of obstructive nephropathy designated mgb for megabladder. Homozygotic mgb mice (mgb-/-) develop lower urinary tract obstruction in utero due to a lack of bladder smooth muscle differentiation. This defect is the result of a random transgene insertion into chromosome 16 followed by a translocation of this fragment into chromosome 11. In an effort to identify potential gene targets affected in mgb mice, we performed transcriptional profiling on embryonic day 15 (E15) mgb-/- bladders using both a Chromosome 11/16 Custom GeneChip Array and the Affymetrix Mouse Genome 430 2.0 GeneChip. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platforms:
GPL5722 GPL1261
36 Samples
Download data: CEL, XLS
Series
Accession:
GSE8715
ID:
200008715

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center