GEO DataSet Links for BioProject (Select 102499) - GEO DataSets

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Items: 2

Select item 2000090121.

Expression data from spontaneous liver tumors of Trim24/TIF1a-null mice.

(Submitter supplied) The transcriptional coregulator Trim24 (formerly known as TIF1a) functions in mice as a liver-specific tumor suppressor. Mice carrying a null mutation in the Trim24 gene all develop hepatocellular carcinoma (HCC). We used microarrays to identify the alterations in gene expression patterns associated with loss of Trim24 and consequent HCC development. Keywords: normal-tumor comparison

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS3087
Platform:: GPL1261
10 Samples

Download data: CEL, CHP, EXP

Series

Accession:: GSE9012

ID:: 200009012

Select item 30872.

Trim24 deficient hepatocellular carcinoma tumors

Analysis of hepatocellular carcinoma (HCC) tumors from animals lacking Trim24 (Tif1alpha). Trim24 is a ligand-dependent nuclear receptor transcriptional co-regulator. Animals lacking Trim24 develop HCC. Results provide insight into the potential role of Trim24 as a liver-specific tumor suppressor.