GEO DataSets

(Submitter supplied) Previously, we demonstrated using a rat model of spinal cord injury (SCI) that bladder wall tissue compliance significantly increased within the first 2 weeks following injury. In order to explore the potential molecular-level mechanisms of this event, the present study quantified molecules pertinent to bladder tissue remodeling and changes in mechanical properties. An initial gene array analysis followed by real-time qPCR revealed that the message levels for tropoelastin and lysyl oxidase were as high as 8-fold in SCI rats compared to normal. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS3507

Platform:

GPL85

4 Samples

Download data: CEL, CHP

Analysis of bladders from Sprague-Dawley females for up to 25 days following spinal cord injury (SCI). Bladder wall tissue compliance increases within 2 weeks after SCI in this animal model. Results provide insight into the molecular basis of the changes that the bladder undergoes after SCI.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 disease state, 4 time sets

Platform:

GPL85

Series:

GSE14096

4 Samples

Download data: CEL, CHP