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Items: 2

1.

Staging of biliary atresia at diagnosis by molecular profiling of the liver

(Submitter supplied) BACKGROUND: Young age at portoenterostomy has been linked to improved outcome in biliary atresia, but pre-existing biological factors may influence the rate of disease progression. In this study, we aimed to determine whether molecular profiling of the liver identifies stages of disease at diagnosis. METHODS: We examined liver biopsies from 47 infants with biliary atresia enrolled in a prospective observational study. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4271
Platform:
GPL570
47 Samples
Download data: CEL
Series
Accession:
GSE15235
ID:
200015235
2.
Full record GDS4271

Infant biliary atresia: liver

Analysis of liver wedge biopsies from infants at diagnosis of biliary atresia (BA). The biopsies underwent histological scoring and were classified as inflammation or fibrosis. Results provide insight into the molecular mechanisms underlying stages of BA disease at diagnosis.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 disease state sets
Platform:
GPL570
Series:
GSE15235
47 Samples
Download data: CEL

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