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Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network (2)

(Submitter supplied) The embryonic stem (ES) cell transcriptional and epigenetic networks are critical for the maintenance of ES cell self-renewal. It remains unclear whether interactions. Here we show that a core member of the Set/MLL complex, WDrepeat protein-5 (Wdr5), is a novel regulator of self-renewal and partners with Oct4 to maintain an intact transcriptional network and for efficient formation of induced pluripotent stem (iPS) cells. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platforms:
GPL6885 GPL6481
9 Samples
Download data: TXT
Series
Accession:
GSE19588
ID:
200019588

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