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Items: 2

1.

Characterization of differential gene expression in adrenocortical tumors harbouring β-catenin (CTNNB1) mutations.

(Submitter supplied) Mutations of β-catenin gene (CTNNB1) are frequent in adrenocortical adenomas (AA) and carcinomas (ACC). However, the target genes of CTNNB1 have not yet been identified in adrenocortical tumors. Our objective was to identify genes de-regulated in adrenocortical tumors harbouring CTNNB1 genetic alterations.
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3912
Platform:
GPL570
8 Samples
Download data: CEL
Series
Accession:
GSE28476
ID:
200028476
2.
Full record GDS3912

Adrenocortical adenomas harboring β-catenin gene CTNNB1 mutations

Analysis of adrenocortical adenomas (AA) with β-catenin missense mutations and AAs with wild-type CTNNB1. Mutations of CTNNB1 are common in AA and adrenocortical carcinomas (ACC). Results provide insight into molecular mechanisms deregulated in adrenocortical tumors with CTNNB1 genetic alterations.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 4 genotype/variation, 3 other, 2 tissue sets
Platform:
GPL570
Series:
GSE28476
8 Samples
Download data: CEL
DataSet
Accession:
GDS3912
ID:
3912

Supplemental Content

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