GEO DataSet Links for BioProject (Select 158945) - GEO DataSets

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Items: 2

Select item 2000372191.

Comparison expression data from wild-type and NFATc1-deficient osteoclasts

(Submitter supplied) Genetic deletion of Nfatc1 in mice results in profound osteoclast-poor osteopetrosis, a high bone mass state caused by a lack of osteoclast activity. We hypothesized that the family of NFATc1 regulated transcripts in the osteoclast would be enriched for genes associated with osteoclast function. We used microarrays profile gene expression in wild-type and NFATc1-deficient osteoclasts generated in vitro to identify NFATc1-dependent transcripts in osteoclasts.

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS5464
Platform:: GPL8321
4 Samples

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Accession:: GSE37219

ID:: 200037219

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 54642.

NFATc1 deficiency effect on osteoclast differentiation in vitro

Analysis of osteoclasts lacking the transcription factor NFATc1. Osteoclasts cultured in the presence of M-CSF and RANKL to induce differentiation. Results identify gene targets of NFATc1 in osteoclastogenesis.