GEO DataSet Links for BioProject (Select 167755) - GEO DataSets

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Items: 2

Select item 2000383761.

Acquired resistance to lapatinib

(Submitter supplied) These studies are aimed at understanding gene expression chnages in a Her2 positive breast cancer cell line that has developed acquired resistance to lapatinib. Samples include SKBR3 parental and resistant (SKBR3-R) under basal conditions and in response to 0.1 and 1uM lapatinib treatment after 24 hours.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4979
Platform:: GPL6947
18 Samples

Download data: TXT

Series

Accession:: GSE38376

ID:: 200038376

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 49792.

Lapatinib effect on lapatinib-resistant ErbB2-positive cell line: dose response

Analysis of lapatinib-resistant ErbB2-positive cells treated with 0.1 or 1 uM lapatinib. Lapatinib is an EGFR/ErbB2 inhibitor used to treat ErbB2‐positive advanced or metastatic breast cancer. Results provide insight into the mechanisms underlying the development of resistance to lapatinib.