GEO DataSet Links for BioProject (Select 181125) - GEO DataSets

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Items: 2

Select item 2000423051.

TREM-1 is a novel therapeutic target in Psoriasis

(Submitter supplied) Our group recently described a population of antigen presenting cells that appear to be critical in psoriasis pathogenesis, termed inflammatory myeloid dendritic cells (CD11c+ BDCA1-). Triggering receptor expressed on myeloid cells type-1 (TREM-1) signaling was a major canonical pathway in the published transcriptome of these cells. TREM-1 is a member of the immunoglobulin superfamily, active through the DAP12 signaling pathway, with an unknown ligand. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4597
Platform:: GPL571
15 Samples

Download data: CEL

Series

Accession:: GSE42305

ID:: 200042305

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 45972.

In vitro model for inflammatory dendritic cells

Analysis of an in vitro model of peptidoglycan-activated monocytes as inflammatory myeloid dendritic cells (DCs). DCs are thought to have an important role in the pathogenesis of inflammatory skin lesions such as psoriasis. Results provide insight into molecular basis of psoriasis pathogenesis.