GEO DataSet Links for BioProject (Select 182210) - GEO DataSets

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Items: 2

Select item 2000425291.

High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1 breast cancer cells.

(Submitter supplied) The traditional method for studying cancer in vitro is to grow immortalized cancer cells in two-dimensional (2D) monolayers on plastic. However, many cellular features are impaired in these unnatural conditions and big alterations in gene expression in comparison to tumors have been reported. Three-dimensional (3D) cell culture models have become increasingly popular and are suggested to be better models than 2D monolayers due to improved cell-to-cell contacts and structures that resemble in vivo architecture. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS5310
Platform:: GPL10558
12 Samples

Download data: TXT

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Accession:: GSE42529

ID:: 200042529

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 53102.

Matrigel 3D culture model of JIMT1 breast cancer cells

Temporal analysis of JIMT1 breast cancer cells cultured as xenografts, in two dimensional cultures, in polyHEMA three dimensional cell cultures, and in Matrigel three dimensional cell cultures. Results provide insight into how closely the Matrigel 3D cell culture model mimics in vivo tumors.