GEO DataSets

(Submitter supplied) Altered myocardial gene expression from heart failure (HF) has mostly been identified by single-point analysis of end-stage disease. This may miss earlier changes in gene expression that are transient and/or directionally opposite to those observed later. By sampling left ventricular myocardial tissue at different time points in a mouse model of cardiomyopathy, we examined differentially expressed transcripts between non-failing controls, early-HF (2 and 3 days after cardiac insult), peak-HF (10 days) and after recovery from HF (28 days). more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS5469

Platform:

GPL6885

19 Samples

Download data: TXT

Temporal analysis of left ventricle myocardium from the MCM model of cardiomyopathy. Transient cardiomyopathy develops in this model after 5 day exposure to tamoxifen, with peak heart failure (HF) at day 10, and resolved HF at day 28. Results provide insight into the molecular basis of evolving HF.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 4 disease state, 5 protocol, 5 time sets

Platform:

GPL6885

Series:

GSE54681

19 Samples

Download data