GEO DataSet Links for BioProject (Select 248178) - GEO DataSets

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Items: 2

Select item 2000578201.

The effect of miRNA-135b overexpression on the gene expression profile of LNCaP cells

(Submitter supplied) MicroRNAs (miRNAs) regulate a wide range of cellular signaling pathways and biological processes in both physiological and pathological states such as cancer. We have previously identified miR-135b as a direct regulator of androgen receptor (AR) protein level in prostate cancer (PCa). We wanted to further explore the relationship of miR-135b to hormonal receptors, particularly estrogen receptor α (ERα). more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS6100
Platform:: GPL10558
12 Samples

Download data: TXT

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Accession:: GSE57820

ID:: 200057820

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 61002.

MicroRNA-135b overexpression effect on prostate cancer cell line: time course

Analysis of LNCaP prostate cancer (PCa) cells overexpressing miRNA-135b for up to 36 hours. LNCaP cells express the androgen receptor (AR). MiRNA-135b overexpression in AR+ PCa cells results in slower growth compared to AR knockdown. Results provide insight into the basis of this slower growth.