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The Essential Rhodobacter sphaeroides RSP1056-RSP0847 (CenKR) Two-Component System Regulated Tol-Pal and Cell Envelope Biosynthesis

(Submitter supplied) To determine the regulon of RSP1056-RSP0847 TCS (response regulator with DNA-binding domains) we used ChIP-seq to determine the genomic occupancy of RSP0847 in strains with a hyperactive (RSP0847(D56E)), WT, and low activity (ΔRSP1056, RSP0847(D56A)) TCS. We then correlated cenR binding sites with changes in global gene expression between WT and strains with a hyperactive (RSP1056(D56E)) or low activity (ΔRSP1056, RSP0847(D56A)) TCS in RNA-seq experiments.
Organism:
Cereibacter sphaeroides 2.4.1
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL30898 GPL30899
53 Samples
Download data: TXT, WIG
Series
Accession:
GSE186600
ID:
200186600

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