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Items: 3

1.

Expression data from adult Rattus liver

(Submitter supplied) Activation of the pregnane X receptor (NR1I2) by drugs and other xenobiotics stimulates (or suppresses) expression of numerous genes involved in the metabolic elimination of foreign compounds and some toxic endogenous substrates. We used microarray analysis to identify genes whose expression in rat liver was significantly altered by pregnenolone 16alpha-carbonitrile (PCN) treatment. Keywords: a single ip injection of PCN (100 mg/kg), 8 h treatment
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Datasets:
GDS2093 GDS2094
Platforms:
GPL341 GPL342
19 Samples
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Series
Accession:
GSE4959
ID:
200004959
2.
Full record GDS2094

Pregnane X receptor agonist effect on the liver (RAE230B)

Analysis of livers of animals treated with pregnenolone 16alpha-carbonitrile (PCN), a pregnane X receptor (NR1I2) agonist. NR1I2 is a member of the nuclear receptor family of ligand-activated transcription factors, and regulates the transcription of genes encoding xenobiotic metabolizing enzymes.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL342
Series:
GSE4959
9 Samples
Download data
3.
Full record GDS2093

Pregnane X receptor agonist effect on the liver (RAE230A)

Analysis of livers of animals treated with pregnenolone 16alpha-carbonitrile (PCN), a pregnane X receptor (NR1I2) agonist. NR1I2 is a member of the nuclear receptor family of ligand-activated transcription factors, and regulates the transcription of genes encoding xenobiotic metabolizing enzymes.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL341
Series:
GSE4959
10 Samples
Download data
Format
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Send to:

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Supplemental Content

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