GEO DataSets

(Submitter supplied) Oligodendrocytes undergo extensive changes as they differentiate from progenitors into myelinating cells. To better understand the molecular mechanisms underlying this transformation, we performed a comparative analysis using gene expression profiling of A2B5+ oligodendrocyte progenitors and O4+ oligodendrocytes. Cells were sort-purified ex vivo from postnatal rat brain using flow cytometry. Using Affymetrix microarrays, 1707 transcripts were identified with a more than twofold increase in expression inO4+oligodendrocytes. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Datasets:

GDS2379 GDS2380

Platforms:

GPL341 GPL342

18 Samples

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Analysis of FACS-purified A2B5+ oligodendrocyte progenitors and O4+ oligodendrocytes from the brains of postnatal day 7 Sprague Dawley males. Results provide insight into the mechanisms underlying oligodendrocyte maturation.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 development stage sets

Platform:

GPL342

Series:

GSE5940

9 Samples

Download data

Analysis of FACS-purified A2B5+ oligodendrocyte progenitors and O4+ oligodendrocytes from the brains of postnatal day 7 Sprague Dawley males. Results provide insight into the mechanisms underlying oligodendrocyte maturation.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 development stage sets

Platform:

GPL341

Series:

GSE5940

9 Samples

Download data