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Links from GEO DataSets

Items: 1 to 20 of 68

1.
Full record GDS1251

Acute hypotension effect on kidneys

Expression profiling of kidneys of 12 week old normotensive Wistar-Kyoto males subjected to acute hypotension by withdrawing 3 ml of blood. Results provide insight into vasoregulatory mechanisms and the genetics and physiology of blood pressure regulation.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 stress sets
Platform:
GPL341
Series:
GSE2401
9 Samples
Download data: CEL, EXP, RPT
DataSet
Accession:
GDS1251
ID:
1251
2.
Full record GDS5255

Diabetic lung

Analysis of lungs of diabetic animals. Diabetes induced by streptozotocin treatment. Results provide insight into the impact of diabetes on the cellular and molecular processes in the lung.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL341
Series:
GSE15900
12 Samples
Download data: CEL
3.
Full record GDS3915

Aging and cognitive decline: hippocampus

Analysis of hippocampi from F344 males, at 5 age points across the adult lifespan, tested on the Morris water maze (MWM) task. MWM is a dorsal hippocampal-dependent, spatial memory task. MWM performance showed an age effect. Results provide insight into the molecular basis of cognitive aging.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 5 age sets
Platform:
GPL341
Series:
GSE9990
49 Samples
Download data: CEL
4.
Full record GDS3850

Peroxisome proliferator-activated receptor-γ ligand treatment: adipose tissue, skeletal muscle, and liver

Analysis of 3 tissue types from lean and insulin resistant, obese Zucker rats untreated or treated with 1 of 4 PPARγ ligands (pioglitazone, rosiglitazone, troglitazone, AG035029). Results provide insight into the role of PPARγ as an essential mediator for maintenance of body insulin sensitivity.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 5 agent, 2 genotype/variation, 3 tissue sets
Platform:
GPL341
Series:
GSE21329
54 Samples
Download data: CEL
5.
Full record GDS3726

Oxidative stress-vulnerable and -resistant neurons

Analysis of neurons from 4 brain regions: hippocampal CA1 and CA3, cerebellar CbG, and cerebral cortex. CA1 and CbG neurons are vulnerable to oxidative stress (OS), CA3 and cerebral cortex neurons resistant. Results provide insight into the molecular basis for selective neuronal vulnerability to OS.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 4 tissue sets
Platform:
GPL341
Series:
GSE7139
12 Samples
Download data: CEL
6.
Full record GDS3700

Night and day effects on pineal gland (Expt. B)

Analysis of pineal glands from Sprague-Dawley rats at mid-day (ZT7) or midnight (ZT19). Similar samples from pineal gland-specific DNF2 transgenic rats also examined. The pineal plays a vital role in vertebrate chronobiology. Results provide insight into night/day changes in pineal gene expression.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 genotype/variation, 2 time sets
Platform:
GPL341
Series:
GSE12342
12 Samples
Download data: CEL
7.
Full record GDS3689

Diesel exhaust particle effect on healthy animals: heart left ventricle

Analysis of heart left ventricle from healthy animals exposed to diesel exhaust (DE) particles. Spontaneously hypertensive animals also examined. DE is linked to cardiovascular impairment. Results suggest DE exposure produces a hypertensive-like cardiac gene expression pattern in healthy animals.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 disease state, 2 stress sets
Platform:
GPL341
Series:
GSE9694
16 Samples
Download data: CEL, CHP
8.
Full record GDS3632

Cadmium effect on hepatocyte in vitro

Analysis of primary cultured hepatocytes exposed to 4 uM cadmium for 3 hours. Cadmium is a potent carcinogen. Results provide insight into the molecular basis of cadmium toxicity.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL341
Series:
GSE8013
8 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS3632
ID:
3632
9.
Full record GDS3605

Spared nerve injury model of peripheral neuropathic pain: dorsal horn of spinal cord

Analysis of adult and neonatal dorsal horns of spinal cords 7 days after spared nerve injury (SNI). SNI is a model for neuropathic pain (NP). Partial peripheral nerve injury in adults result in NP-like hypersensitivity, but not in neonates. Results provide insight into the molecular basis of NP.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 development stage, 2 protocol sets
Platform:
GPL341
Series:
GSE18803
24 Samples
Download data: CEL
10.
Full record GDS3369

Zinc inhalation effect on the heart: dose response

Analysis of hearts of animals after subchronic exposure to zinc via nose only inhalation of aerosolized zinc sulfate (10, 30 or 100 ug zinc/m3), for 5 hours/day, 3 days/week for 16 weeks. Results provide insight into the effect of inhalation of zinc at environmentally relevant levels on the heart.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent, 4 dose sets
Platform:
GPL341
Series:
GSE11091
24 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS3369
ID:
3369
11.
Full record GDS3224

Heart left ventricle and diaphragm comparison

Analysis of normal heart left ventricle and diaphragm of young-adult Sprague Dawley males. Concurrent rhythmic contractions of the diaphragm and heart are needed to sustain life. Results provide insight into transcriptional strategies for ensuring long-term energy supplies in these two muscles.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 tissue sets
Platform:
GPL341
Series:
GSE6943
12 Samples
Download data: CEL
DataSet
Accession:
GDS3224
ID:
3224
12.
Full record GDS3157

Inherited cryptorchidism model: fetal testis

Analysis of testis of cryptorchid (orl) fetuses at at various gestational days up to GD19. The orl strain is at high risk for cryptorchidism, or undescended testis, one of the most common congenital anomalies in humans. Results provide insight into molecular mechanisms underlying cryptorchidism.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 age, 2 strain sets
Platform:
GPL341
Series:
GSE7755
20 Samples
Download data: CEL
DataSet
Accession:
GDS3157
ID:
3157
13.
Full record GDS3156

Inherited cryptorchidism model: fetal gubernaculum

Analysis of gubernaculum of cryptorchid (orl) fetuses at various gestational days up to GD20. The orl strain is at high risk for cryptorchidism, or undescended testis, one of the most common congenital anomalies in humans. Results provide insight into molecular mechanisms underlying cryptorchidism.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 3 age, 2 gender, 3 other, 2 strain sets
Platform:
GPL341
Series:
GSE7755
34 Samples
Download data: CEL
DataSet
Accession:
GDS3156
ID:
3156
14.
Full record GDS3153

Diabetes model: heart

Analysis of heart left ventricles of diabetic animals. Diabetes induced by streptozotocin treatment. Results provide insight into the molecular mechanisms underlying diabetes-induced cardiac dysfunction.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL341
Series:
GSE6880
6 Samples
Download data: CEL
DataSet
Accession:
GDS3153
ID:
3153
15.
Full record GDS3143

Insectide chlorpyrifos effect on the brain: dose response

Analysis of brain frontal lobes of animals treated with chlorpyrifos (CPF) at doses up to 30 mg/kg. Subtoxic exposure to CPF, an organophosphorus insecticide, has long-term adverse effects on brain development. Results provide insight into the molecular mechanisms underlying these effects.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent, 7 dose sets
Platform:
GPL341
Series:
GSE9751
44 Samples
Download data: CEL
DataSet
Accession:
GDS3143
ID:
3143
16.
Full record GDS3130

CA1 and CA3 hippocampal slice cultures response to oxidative stress: time course

Anlaysis of CA1 and CA3 hippocampal slice cultures for up to 12 hours following treatment with duroquinone to induce oxidative stress (OS). Neurons in the CA1 region are sensitive to OS, while those in CA3 are resistant. Results provide insight into the molecular basis of this difference.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 4 time, 2 tissue sets
Platform:
GPL341
Series:
GSE6693
16 Samples
Download data: CEL
17.
Full record GDS3084

Liver during a 24-hour (12 hour light:12 hour dark) cycle

Analysis of livers of Wistar animals during a 24-hour period, from zeitgeber time (ZT) 0.25 to ZT 23.75. Results provide insight into baseline patterns of gene expression in normal liver within the 24 hour circadian cycle.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 18 time sets
Platform:
GPL341
Series:
GSE8988
54 Samples
Download data: CEL
18.
Full record GDS3083

Skeletal muscle during a 24-hour (12 hour light:12 hour dark) cycle

Analysis of gastrocnemius muscles of Wistar animals during a 24-hour period, from zeitgeber time (ZT) 0.25 to ZT 23.75. Results provide insight into baseline patterns of gene expression in normal skeletal muscle within the 24 hour circadian cycle.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 18 time sets
Platform:
GPL341
Series:
GSE8989
54 Samples
Download data: CEL
19.
Full record GDS3074

Hypertension models: resistance arteries

Analysis of small diameter branches of the saphenous artery from spontaneously hypertensive (SHR) and adrenocorticotropic hormone (ACTH)-induced hypertensive animals. The saphenous artery is a resistance artery. Results provide insight molecular mechanisms contributing to hypertension.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent, 2 disease state, 2 strain sets
Platform:
GPL341
Series:
GSE8051
9 Samples
Download data: CEL, CHP, EXP
20.
Full record GDS3050

Male and female lungs response to hantavirus infection: time course

Analysis of male and female lungs at various time points up to 40 days post-infection with Seoul hantavirus. Males and females differ in their susceptibility to several RNA and DNA viruses. Results provide insight into the influence of gender in the response to Seoul hantavirus infections.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 gender, 2 infection, 4 time sets
Platform:
GPL341
Series:
GSE7271
24 Samples
Download data: CEL
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