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Links from GEO DataSets

Items: 1 to 20 of 107

1.
Full record GDS3701

Night and day effects on pineal gland and various other tissues (Expt. C)

Analysis of pineal glands and other tissues (retina, neocortex, cerebellum, hypothalamus, heart, and liver) obtained from Sprague-Dawley rats at mid-day (ZT7) or midnight (ZT19). Results provide insight into genes that characterize the pineal gland, independent of tonic or night/day influences.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 time, 7 tissue sets
Platform:
GPL1355
Series:
GSE12343
20 Samples
Download data: CEL
2.
Full record GDS5604

Fibroblast growth factor 2 effect on lens epithelia explant cultures: time course

Analysis of lens explant cultures grown overnight in the presence of 5 ng/mL FGF2 to promote proliferation and survival, then treated with 100 ng/mL FGF2 for up to 24hr to induce differentiation. Results provide insight into the molecular basis of FGF2-induced lens fiber cell differentiation.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 growth protocol, 5 time sets
Platform:
GPL1355
Series:
GSE50604
10 Samples
Download data: CEL
3.
Full record GDS5390

Whey protein hydrolysate diet effect on exercised epitrochlearis muscle

Analysis of epitrochlearis muscle from males exercised for 2hr then fed a whey protein hydrolysate (WPH) diet or a control diet with an identical amino acid composition (AAM). Results provide insight into the molecular basis of the greater post-exercise muscle protein synthesis in the WPH group.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 protocol sets
Platform:
GPL1355
Series:
GSE49486
8 Samples
Download data: CEL
DataSet
Accession:
GDS5390
ID:
5390
4.
Full record GDS5283

Hexahydro-1,3,5-trinitro-1,3,5-triazine effect on the liver: dose response and time course

Analysis of livers of males for up to 48 hours after treatment with a single, oral, nonseizure-inducing dose of 3 or 18 mg/kg hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX). RDX is a synthetic, high-impact, stable explosive. Results provide insight into the acute effects of RDX on the liver.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 dose, 4 time sets
Platform:
GPL1355
Series:
GSE12196
24 Samples
Download data: CEL
DataSet
Accession:
GDS5283
ID:
5283
5.
Full record GDS5282

Hexahydro-1,3,5-trinitro-1,3,5-triazine effect on the brain: dose response and time course

Analysis of cerebral cortices of males for up to 48 hours after treatment with an oral, nonseizure-inducing dose of 3 or 18 mg/kg hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX). RDX is a synthetic, high-impact, stable explosive. Results provide insight into the acute effects of RDX on the brain.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 dose, 4 time sets
Platform:
GPL1355
Series:
GSE12196
24 Samples
Download data: CEL
DataSet
Accession:
GDS5282
ID:
5282
6.
Full record GDS5257

Calyx of Held synaptic development: globular bushy cells

Analysis of calyx of Held globular bushy cells at different maturation stages: P3, P8 and P21. Calyx of Held presynaptic terminals in the auditory brainstem develop into axosomatic synapses. Results provide insight into mechanisms underlying development of mammalian synaptic structure and function.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 3 cell type, 3 development stage sets
Platform:
GPL1355
Series:
GSE49599
20 Samples
Download data: CEL
DataSet
Accession:
GDS5257
ID:
5257
7.
Full record GDS5252

Bacterial lipopolysaccharide endotoxin stimulation effect on hepatic stellate cells: time course (experiment 1)

Analysis of hepatic stellate cells (HSCs) cultured with LPS for 1, 3, 6, 12, 24 hr. During exposure to toxins such as LPS, the liver suffers inflammatory injury. Results provide insight into molecular mechanisms underlying hepatic inflammatory and immune responses.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent, 5 time sets
Platform:
GPL1355
Series:
GSE49980
11 Samples
Download data: CEL
8.
Full record GDS5251

Bacterial lipopolysaccharide endotoxin stimulation effect on hepatic stellate cells: time course (experiment 2)

Analysis of hepatic stellate cells (HSCs) cultured with LPS for 1 and 24 hr. During exposure to toxins such as LPS, the liver suffers inflammatory injury. Results provide insight into molecular mechanisms underlying hepatic inflammatory and immune responses.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent, 2 time sets
Platform:
GPL1355
Series:
GSE49980
8 Samples
Download data: CEL
9.
Full record GDS5246

Oligodendroglial cell model of multiple system atrophy: time course

Analysis of oligodendroglia stably expressing α-synuclein and transiently expressing p25α for up to 16 hrs. Coexpression of α -synuclein and p25α causes a degenerative phenotype modeling multiple system atrophy (MSA). Results provide insight into the molecular basis of MSA pathogenesis.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 protocol, 3 time sets
Platform:
GPL1355
Series:
GSE51781
12 Samples
Download data: CEL
10.
Full record GDS5215

Molecular hydrogen-saturated water consumption effect on the liver

Analysis of livers of Sprague-Dawley animals following consumption of water containing 0.7 mM dissolved molecular hydrogen for 4 weeks. Molecular hydrogen is an antioxidant. Results provide insight into the molecular response of the liver to hydrogen saturated water.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL1355
Series:
GSE26363
8 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS5215
ID:
5215
11.
Full record GDS5063

Conventional cigarette or modified-risk tobacco product smoke effect on lung bronchial epithelium: dose response

Analysis of left lung bronchi from males that were nose-only exposed for 28 days to smoke from reference cigarette 3R4F at doses up to 23ug nicotine/l or from a modified risk tobacco product (MRTP) at a dose of 23ug nicotine/l. Results provide insight into the reduced biological activity of MRTP.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 3 agent, 4 dose sets
Platform:
GPL1355
Series:
GSE50254
25 Samples
Download data: CEL
DataSet
Accession:
GDS5063
ID:
5063
12.
Full record GDS5062

Conventional cigarette or modified-risk tobacco product smoke effect on lung parenchyma: dose response

Analysis of left lung parenchyma from males that were nose-only exposed for 28 days to smoke from reference cigarette 3R4F at doses up to 23ug nicotine/l or from a modified risk tobacco product (MRTP) at a dose of 23ug nicotine/l. Results provide insight into the reduced biological activity of MRTP.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 3 agent, 4 dose sets
Platform:
GPL1355
Series:
GSE50254
25 Samples
Download data: CEL
DataSet
Accession:
GDS5062
ID:
5062
13.
Full record GDS5061

Conventional cigarette or modified-risk tobacco product smoke effect on nasal respiratory epithelium: dose response

Analysis of nasal epithelia from males that were nose-only exposed for 28 days to smoke from reference cigarette 3R4F at doses up to 23ug nicotine/l or from a modified risk tobacco product (MRTP) at a dose of 23ug nicotine/l. Results provide insight into the reduced biological activity of MRTP.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 3 agent, 4 dose sets
Platform:
GPL1355
Series:
GSE50254
25 Samples
Download data: CEL
DataSet
Accession:
GDS5061
ID:
5061
14.
Full record GDS5034

Polybrominated diphenyl ether effect on the liver

Analysis of livers collected from postnatal day (PND) 22 and 13-week-old Wistar/Han rats exposed in utero to polybrominated diphenyl ether (PBDE) and directly dosed with PBDE. PBDEs are flame retardants. Results provide insight into the molecular basis of PBDE toxicities.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 age, 2 agent, 2 gender sets
Platform:
GPL1355
Series:
GSE32156
30 Samples
Download data: CEL
15.
Full record GDS5033

Diencephalon response to short-term dietary zinc deficiency followed by zinc recovery

Analysis of diencephalon from Sprague-Dawley males fed a zinc-deficient diet for 10 days then a control diet for 6 days. The zinc recovery restored food intake behaviors and salt preferences. Results provide insight into the molecular effects of short-term zinc deficiency and recovery on the brain.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 growth protocol sets
Platform:
GPL1355
Series:
GSE31430
8 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS5033
ID:
5033
16.
Full record GDS5032

Early postnatal nerve tissue response to acrylamide: sciatic nerve

Analysis of sciatic nerve from 3 week-old male Wistar pups treated daily with acrylamide (30 mg/kg) for 21 days. Acrylamide is a type-2 alkene monomer with established human neurotoxic effects. Results provide insight into the molecular basis of acrylamide neurotoxicity in developing nervous tissue.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL1355
Series:
GSE29004
4 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS5032
ID:
5032
17.
Full record GDS5031

Early postnatal nerve tissue response to acrylamide: spinal cord

Analysis of spinal cord from 3 week-old male Wistar pups treated daily with acrylamide (30 mg/kg) for 21 days. Acrylamide is a type-2 alkene monomer with established human neurotoxic effects. Results provide insight into the molecular basis of acrylamide neurotoxicity in developing nervous tissue.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL1355
Series:
GSE29004
4 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS5031
ID:
5031
18.
Full record GDS4954

Cobalt effect on liver cell line MH1C1: dose response

Analysis of MH1C1 liver cells exposed to 160 or 310 uM cobalt chloride. Cobalt (Co) is a heavy metal found naturally in low concentrations and used in military and industrial applications. Co exposure can result in adverse health effects. Results provide insight into the mechanisms of Co toxicity.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 agent, 3 dose sets
Platform:
GPL1355
Series:
GSE51207
12 Samples
Download data: CEL
19.
Full record GDS4953

Cobalt effect on liver cell line H4IIEC3: dose response

Analysis of H4IIEC3 liver cells exposed to 29 or 62 uM cobalt chloride. Cobalt (Co) is a heavy metal found naturally in low concentrations and used in military and industrial applications. Co exposure can result in adverse health effects. Results provide insight into the mechanisms of Co toxicity.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 agent, 3 dose sets
Platform:
GPL1355
Series:
GSE51207
12 Samples
Download data: CEL
20.
Full record GDS4940

Hippocampus response to acetylcholinesterase inhibitor soman: time course

Analysis of hippocampi of Sprauge-Dawley males for up to 168 hours following exposure to the acetylcholinesterase inhibitor soman. Soman is a potent neurotoxicant. Results provide insight into the molecular pathogenesis of soman-induced neurodegeneration.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 3 agent, 10 time sets
Platform:
GPL1355
Series:
GSE13428
38 Samples
Download data: CEL
DataSet
Accession:
GDS4940
ID:
4940
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