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Links from GEO DataSets

Items: 8

1.
Full record GDS3929

Tobacco smoke effect on maternal and fetal cells

Analysis of peripheral blood leukocytes and placenta of pregnant smokers. Umbilical cord blood leukocytes of their newborns also examined. Maternal smoking has a negative effect on all stages of pregnancy. Results provide insight into molecular mechanisms underlying tobacco smoke-related defects.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state, 3 specimen sets
Platform:
GPL6883
Series:
GSE27272
183 Samples
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DataSet
Accession:
GDS3929
ID:
3929
2.
Full record GDS5625

DNA methyltransferase inhibitor 5-aza-2’-deoxycytidine effect on oral cancer cell lines

Analysis of oral squamous cell carcinoma (OSCC) cell lines: OC3, SAS, SCC-15, and HSC3, treated with 5-aza-2’-deoxycytidine (AzC), an inhibitor of DNA methyltransferase. Results provide insight into potential tumor suppressor genes silenced by DNA hypermethylation in OSCC.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 4 cell line sets
Platform:
GPL6883
Series:
GSE38823
16 Samples
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3.
Full record GDS5210

CSN5 depletion effect on hepatocellular carcinoma cell lines

Analysis of Huh7 and HepG2 hepatocellular carcinoma (HCC) cells depleted for CSN5, the fifth subunit of the COP9 signalosome. CSN5 expression is elevated in early HCC. Result provide insight into the role of CSN5 in the pathogenesis of HCC.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 cell line, 2 protocol sets
Platform:
GPL6883
Series:
GSE26485
16 Samples
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4.
Full record GDS5173

G-protein coupled receptor kinase 3 expression effect on prostate cancer cell line

Analysis of PC3 prostate cancer cells expressing G-protein coupled receptor kinase 3 (GRK3). Results provide insight into the role of GRK3 in prostate cancer progression and metastasis.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL6883
Series:
GSE36022
6 Samples
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5.
Full record GDS4831

COP1 depletion effect on hepatocellular carcinoma cell lines

Analysis of Huh7, HepG2, and Hep3B hepatocellular carcinoma (HCC) cells depleted for the ubiquitin modulator COP1. COP1 regulates p53 activity by ubiquitination. p53 is wild type in HepG2, mutated in Huh7, and lacking in Hep3B. Results provide insight into the role of COP1 in HCC pathogenesis.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 cell line, 2 protocol sets
Platform:
GPL6883
Series:
GSE21955
22 Samples
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6.
Full record GDS3963

Pre-diabetes and Type 2 Diabetes mellitus: blood

Analysis of blood after an overnight fast from Impaired Fasting Glucose, commonly called pre-diabetes, and Type 2 Diabetes mellitus (T2D) male patients. These results, together with miRNA profiling, provide insight into the mechanisms underlying the transition from pre-diabetes to overt T2D.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 disease state sets
Platform:
GPL6883
Series:
GSE26168
24 Samples
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7.
Full record GDS3898

Social isolation effect on peripheral blood mononuclear cells

Analysis of PBMCs from chronically lonely, older adults. Lack of close social ties is a well-established risk factor for diseases involving the immune system and inflammation. Results provide insight into the molecular mechanisms underlying those effects.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 individual sets
Platform:
GPL6883
Series:
GSE25837
93 Samples
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8.
Full record GDS3783

Jurkat T cell response to silver nanoparticles

Analysis of Jurkat T cells exposed to to 0.2 mg/L of silver nanoparticles (AgNPs) and Ag ions for 24 hours. Cell viability screening revealed that Jurkat T cells exhibit higher sensitivity to AgNPs than to Ag ions. Results provide insight into the molecular basis of this difference in sensitivity.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 stress sets
Platform:
GPL6883
Series:
GSE20692
9 Samples
Download data
DataSet
Accession:
GDS3783
ID:
3783
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