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Links from GEO DataSets

Items: 13

1.
Full record GDS3982

C-peptide effect on streptozotocin-induced type 1 diabetes: kidney proximal tubular cells

Analysis of kidney proximal tubular cells of streptozotocin-induced, type 1 diabetes (T1D) rats treated with C-peptide for 2 hours. Proinsulin C-peptide exerts renoprotective effects in T1D. Results provide insight into molecular mechanisms underlying the protective effects of C-peptide.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL6247
Series:
GSE24687
5 Samples
Download data: CEL
DataSet
Accession:
GDS3982
ID:
3982
2.
Full record GDS5434

Articular and growth plate cartilage zones: 10-day old normal proximal tibia

Analysis of superficial (SZ) and intermediate/deep (IDZ) zones microdissected from articular cartilage and resting (RZ) zone from growth plate cartilage of proximal tibial epiphyses of 10-day old rats. Results provide insight into molecular basis of articular and growth plate cartilage divergence.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 3 tissue sets
Platform:
GPL6247
Series:
GSE54216
12 Samples
Download data: CEL
3.
Full record GDS5345

Dietary vitamin D3 supplementation effect on hippocampus: dose effect

Analysis of hippocampus from F344 rats fed dietary supplement of cholecalciferol (vitamin D3) at doses of 10,000, 1000 and 100 IU/kg diet for 18 weeks. Results provide insight into molecular mechanisms underlying vitamin D-mediated synaptic function enhancement.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 3 dose sets
Platform:
GPL6247
Series:
GSE61326
26 Samples
Download data: CEL
4.
Full record GDS5223

Nuclear hormone receptor NR4A1 deficiency effect on FHH model of hypertension-associated renal disease: time course

Analysis of kidney from 8-24 week-old, Nr4a1-deficient (Nr4a1−/−) animals developed on the genetic background of the Fawn-Hooded Hypertensive (FHH) rat. The FHH model is susceptible to kidney injury. Results provide insight into the role of Nr4a1 in the pathogenesis of kidney disease.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 genotype/variation, 3 time sets
Platform:
GPL6247
Series:
GSE54714
18 Samples
Download data: CEL, CHP
5.
Full record GDS5007

Fetal and neonatal ductus arteriosus and aorta: endothelial cells

Analysis of endothelial cells (ECs) isolated from the ductus arteriosus (DA) and aorta of fetuses and neonates. The DA, a fetal shunt artery between the pulmonary artery and the aorta, closes immediately after birth. Results provide insight into EC involvement in DA-specific morphology and function.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 development stage, 2 tissue sets
Platform:
GPL6247
Series:
GSE40500
12 Samples
Download data: CEL
6.
Full record GDS4908

Postinfarction heart failure model: peripheral blood mononuclear cells

Analysis of PBMCs from males subjected to left coronary artery ligation to induce large myocardial infarctions (MI). Only animals with large MIs develop LV remodeling and heart failure (HF). Results provide insight into the molecular basis of the progression of LV remodeling and HF.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 3 disease state, 2 protocol sets
Platform:
GPL6247
Series:
GSE47495
11 Samples
Download data: CEL
7.
Full record GDS4907

Postinfarction heart failure model: left ventricle

Analysis of LV from males subjected to left coronary artery ligation to induce large, moderate, or small myocardial infarctions (MI). Only animals with large MIs develop LV remodeling and heart failure (HF). Results provide insight into the molecular basis of the progression of LV remodeling and HF.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 3 disease state, 4 protocol sets
Platform:
GPL6247
Series:
GSE47495
23 Samples
Download data: CEL
8.
Full record GDS4563

Passive loading effect on gastrocnemius muscle of intensive care unit model: time course

Temporal analysis of loaded leg gastrocnemius of females (subjected to neuromuscular blockade, mechanical ventilation) following unilateral passive mechanical loading (PML). Results provide insight into molecular basis of the beneficial effects of PML on muscle mass and function in this ICU model.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 protocol, 3 time sets
Platform:
GPL6247
Series:
GSE37944
46 Samples
Download data: CEL
9.
Full record GDS4429

Fetal brain response to maternal immune activation induced by lipopolysaccharide

Analysis of fetal brains following maternal immune activation (MIA) induced by treating pregnant dams with lipopolysaccharide. MIA is a risk factor for the development of schizophrenia and autism. Results provide insight into the effect of MIA on the fetal brain at the molecular level.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 agent sets
Platform:
GPL6247
Series:
GSE34058
19 Samples
Download data: CEL
10.
Full record GDS4411

cAMP agonist forskolin effect on INS-1 insulinoma cell line: time course

Analysis of insulinoma cells after short-term (2hr) and long-term (16hr) stimulation with cAMP agonist forskolin. Incretin hormone GLP-1 enhances islet cell survival via cAMP pathway induction in beta cells. Results provide insight into mechanisms by which GLP-1 promotes pancreatic islet viability.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 agent, 2 time sets
Platform:
GPL6247
Series:
GSE31736
4 Samples
Download data: CEL, CHP
11.
Full record GDS4048

Ovarian primordial follicle response to various growth factors

Analysis of P4 ovaries of Sprague-Dawley females exposed to growth factors. Ovarian primordial follicles are critical for female reproduction and comprise a finite pool of gametes arrested in development. Results provide insight into molecular mechanisms underlying primordial follicle development.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 10 agent sets
Platform:
GPL6247
Series:
GSE20324
44 Samples
Download data: CEL
12.
Full record GDS4010

Effect of dietary obesity in fathers on islets of female offspring

Analysis of pancreatic islets of control diet (CD)-fed, 13 week old female offspring of high-fat-diet (HFD)-fed Sprague-Dawley males mated with CD-fed females. Results provide insight into molecular mechanisms contributing to Type 2 diabetes-related impairments seen in offspring of obese fathers.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 growth protocol sets
Platform:
GPL6247
Series:
GSE19877
11 Samples
Download data: CEL
13.
Full record GDS3832

Complement protein C1q effect on immature neurons

Analysis of primary cortical neurons stimulated with C1q. In vitro, C1q, in the absence of other complement proteins, improves neuronal viability, neurite outgrowth and prevents β-amyloid-induced neuronal death. Results provide insight into the molecular basis of the neuroprotective role of C1q.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL6247
Series:
GSE18860
6 Samples
Download data: CEL, CHP
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