GEO DataSets

Analysis of lapatinib-resistant ErbB2-positive cells treated with 0.1 or 1 uM lapatinib. Lapatinib is an EGFR/ErbB2 inhibitor used to treat ErbB2‐positive advanced or metastatic breast cancer. Results provide insight into the mechanisms underlying the development of resistance to lapatinib.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 cell type, 3 dose sets

Platform:

GPL6947

Series:

GSE38376

18 Samples

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Analysis of RWPE-1 prostate epithelial cells following silencing of miR-205. miR-205 silenced using an antisense locked nucleic acid targeting miR-205. Results provide insight into the role of miR-205 in prostate epithelial cells.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 protocol sets

Platform:

GPL6947

Series:

GSE29782

6 Samples

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Analysis of PBMCs from patients with idiopathic pulmonary arterial hypertension (IPAH), systemic sclerosis (SSc), SSc associated PAH (SSc-PAH), and SSc complicated by interstitial lung disease and PH (SSc-PH-ILD). Results provide insight into the molecular basis of the various disease groups.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 5 disease state sets

Platform:

GPL6947

Series:

GSE33463

140 Samples

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Analysis of peripheral blood mononuclear cells (PBMCs) from osteoarthritis (OA) patients. Patients participated in the Genetics osteoARthritis and Progression (GARP) study. Results provide insight into the feasibility of using gene expression profiling of PBMCs to detect the onset of OA.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state, 2 gender sets

Platform:

GPL6947

Series:

GSE48556

139 Samples

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Analysis of MDA-MD-231 breast cancer cell line transfected with siRNAs against RBP2. RBP2 is a histone demethylase (also known as JARID1A and KDM5A) associated with breast cancer metastasis. Results provide insight into roles of RBP2 in breast cancer metastasis.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 3 protocol sets

Platform:

GPL6947

Series:

GSE49119

9 Samples

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Analysis of AGS cells treated with mycophenolic acid (MPA; 2ug/ml) for up to 72hr. MPA is an immunosuppressive drug used to prevent graft rejection. Results provide insight into molecular mechanisms underlying the broad anticancer activities of MPA.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 agent, 5 time sets

Platform:

GPL6947

Series:

GSE46671

12 Samples

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Analysis of whole blood samples from patients with ankylosing spondylitis (AS). AS is a chronic inflammatory rheumatic disease characterized by inflammation that leads to bone resorption and bone formation. Results provide insight into the molecular pathogenesis of AS.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state sets

Platform:

GPL6947

Series:

GSE25101

32 Samples

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Analysis of postmortem midbrain specimens from individuals who died from cocaine abuse. Midbrain dopamine-synthesizing neurons play a important role in the addiction process. Results provide insight into the molecular pathophysiological changes in the midbrain associated with cocaine abuse.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 agent, 20 individual sets

Platform:

GPL6947

Series:

GSE54839

60 Samples

Download data: IDAT

Analysis of cultured airway epithelial cells (AECs) treated with IL-13 for 21 days. IL-13 induces mucous production. Excess airway mucous secretion is a feature of chronic lung diseases. Results provide insight into the molecular processes responsible for mucous production driven by IL-13 in AECs.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 agent sets

Platform:

GPL6947

Series:

GSE37693

8 Samples

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Analysis of whole blood samples from survivors and non-survivors of sepsis for up to 5 days after their admission to the intensive care unit. Results provide insight into the molecular basis of the immune dysfunction resulting from sepsis.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state, 54 individual, 3 other, 5 time sets

Platform:

GPL6947

Series:

GSE54514

163 Samples

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Analysis of SKOV3 ovarian cancer xenograft tumors treated with trastuzumab (TZ), pertuzumab (PZ), or both. TZ and PZ target Human Epidermal Growth Factor Receptor 2 (HER2). Combined therapy results in enhanced antitumor activity. Results provide insight into the molecular basis of this enhancement.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 4 agent sets

Platform:

GPL6947

Series:

GSE31432

23 Samples

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Analysis of three large B-cell lymphoma cell lines treated with the histone deacetylase inhibitor panobinostat, hypomethylating agent decitabine, or both for 48hrs. Panobinostat synergizes with decitabine in DLBCL cells. Results provide insight into the molecular basis for this synergistic effect.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 4 agent, 3 cell line sets

Platform:

GPL6947

Series:

GSE27226

12 Samples

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Analysis of whole blood (WB) from critically ill influenza and bacterial pneumonia patients for up to 5 days, and WB from before and 7 days post-influenza vaccination volunteers. Results provide insight into the role of host response in influencing disease progression in influenza A infection.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 disease state, 7 time sets

Platform:

GPL6947

Series:

GSE20346

81 Samples

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