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Links from GEO DataSets

Items: 13

1.
Full record GDS4979

Lapatinib effect on lapatinib-resistant ErbB2-positive cell line: dose response

Analysis of lapatinib-resistant ErbB2-positive cells treated with 0.1 or 1 uM lapatinib. Lapatinib is an EGFR/ErbB2 inhibitor used to treat ErbB2‐positive advanced or metastatic breast cancer. Results provide insight into the mechanisms underlying the development of resistance to lapatinib.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 cell type, 3 dose sets
Platform:
GPL6947
Series:
GSE38376
18 Samples
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2.
Full record GDS5525

miR-205 silencing effect on prostate epithelial cell line

Analysis of RWPE-1 prostate epithelial cells following silencing of miR-205. miR-205 silenced using an antisense locked nucleic acid targeting miR-205. Results provide insight into the role of miR-205 in prostate epithelial cells.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 protocol sets
Platform:
GPL6947
Series:
GSE29782
6 Samples
Download data
3.
Full record GDS5499

Pulmonary hypertensions: PBMCs

Analysis of PBMCs from patients with idiopathic pulmonary arterial hypertension (IPAH), systemic sclerosis (SSc), SSc associated PAH (SSc-PAH), and SSc complicated by interstitial lung disease and PH (SSc-PH-ILD). Results provide insight into the molecular basis of the various disease groups.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 5 disease state sets
Platform:
GPL6947
Series:
GSE33463
140 Samples
Download data
4.
Full record GDS5363

Osteoarthritis: peripheral blood mononuclear cells

Analysis of peripheral blood mononuclear cells (PBMCs) from osteoarthritis (OA) patients. Patients participated in the Genetics osteoARthritis and Progression (GARP) study. Results provide insight into the feasibility of using gene expression profiling of PBMCs to detect the onset of OA.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state, 2 gender sets
Platform:
GPL6947
Series:
GSE48556
139 Samples
Download data
DataSet
Accession:
GDS5363
ID:
5363
5.
Full record GDS5355

Histone demethylase RBP2 deficiency effect on MDA-MD-231 breast cancer cell line

Analysis of MDA-MD-231 breast cancer cell line transfected with siRNAs against RBP2. RBP2 is a histone demethylase (also known as JARID1A and KDM5A) associated with breast cancer metastasis. Results provide insight into roles of RBP2 in breast cancer metastasis.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 protocol sets
Platform:
GPL6947
Series:
GSE49119
9 Samples
Download data
6.
Full record GDS5265

Mycophenolic acid effect on AGS gastric cancers cells: time course

Analysis of AGS cells treated with mycophenolic acid (MPA; 2ug/ml) for up to 72hr. MPA is an immunosuppressive drug used to prevent graft rejection. Results provide insight into molecular mechanisms underlying the broad anticancer activities of MPA.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent, 5 time sets
Platform:
GPL6947
Series:
GSE46671
12 Samples
Download data
7.
Full record GDS5231

Ankylosing spondylitis: blood

Analysis of whole blood samples from patients with ankylosing spondylitis (AS). AS is a chronic inflammatory rheumatic disease characterized by inflammation that leads to bone resorption and bone formation. Results provide insight into the molecular pathogenesis of AS.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state sets
Platform:
GPL6947
Series:
GSE25101
32 Samples
Download data
8.
Full record GDS5047

Cocaine abuse effect on the midbrain

Analysis of postmortem midbrain specimens from individuals who died from cocaine abuse. Midbrain dopamine-synthesizing neurons play a important role in the addiction process. Results provide insight into the molecular pathophysiological changes in the midbrain associated with cocaine abuse.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 20 individual sets
Platform:
GPL6947
Series:
GSE54839
60 Samples
Download data: IDAT
9.
Full record GDS4981

Airway epithelial cell response to IL-13 in vitro

Analysis of cultured airway epithelial cells (AECs) treated with IL-13 for 21 days. IL-13 induces mucous production. Excess airway mucous secretion is a feature of chronic lung diseases. Results provide insight into the molecular processes responsible for mucous production driven by IL-13 in AECs.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent sets
Platform:
GPL6947
Series:
GSE37693
8 Samples
Download data
10.
Full record GDS4971

Blood from septic patients: time course

Analysis of whole blood samples from survivors and non-survivors of sepsis for up to 5 days after their admission to the intensive care unit. Results provide insight into the molecular basis of the immune dysfunction resulting from sepsis.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state, 54 individual, 3 other, 5 time sets
Platform:
GPL6947
Series:
GSE54514
163 Samples
Download data
DataSet
Accession:
GDS4971
ID:
4971
11.
Full record GDS4814

Ovarian cancer xenograft tumor response to trastuzumab and pertuzumab

Analysis of SKOV3 ovarian cancer xenograft tumors treated with trastuzumab (TZ), pertuzumab (PZ), or both. TZ and PZ target Human Epidermal Growth Factor Receptor 2 (HER2). Combined therapy results in enhanced antitumor activity. Results provide insight into the molecular basis of this enhancement.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 4 agent sets
Platform:
GPL6947
Series:
GSE31432
23 Samples
Download data
12.
Full record GDS4006

Histone deacetylase inhibitor and hypomethylating agent effect on diffuse large B-cell lymphoma cell lines

Analysis of three large B-cell lymphoma cell lines treated with the histone deacetylase inhibitor panobinostat, hypomethylating agent decitabine, or both for 48hrs. Panobinostat synergizes with decitabine in DLBCL cells. Results provide insight into the molecular basis for this synergistic effect.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 4 agent, 3 cell line sets
Platform:
GPL6947
Series:
GSE27226
12 Samples
Download data
13.
Full record GDS3919

Severe influenza A infection: whole blood

Analysis of whole blood (WB) from critically ill influenza and bacterial pneumonia patients for up to 5 days, and WB from before and 7 days post-influenza vaccination volunteers. Results provide insight into the role of host response in influencing disease progression in influenza A infection.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 disease state, 7 time sets
Platform:
GPL6947
Series:
GSE20346
81 Samples
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