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Links from GEO DataSets

Items: 1 to 20 of 601

1.
Full record GDS5004

Adult alveolar type 2 and embryonic bipotent progenitor lung cells

Analysis of adult alveolar type (AT) 2 and E18 bipotent progenitor (BP) lung cells. During development, AT1 and AT2 cells arise from a BP; after birth, new AT1 cells derive from rare, long-lived, self-renewing mature AT2 cells. Results provide insight into the molecular basis of AT2 self-renewal.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 age, 2 cell type sets
Platform:
GPL1261
Series:
GSE49346
6 Samples
Download data: CEL, CHP
2.
Full record GDS5813

Bone morphogenetic protein 4 and forskolin effect on embryonic AGM VE-cadherin+ cells

Analysis of vascular endothelial (VE)-cadherin+ cells isolated from aorta-gonad-mesonephros (AGM) region of E11.5 embryos then treated with bone morphogenetic protein (BMP) 4, adenylyl cyclase activator forskolin, or both. Results provide insight into the role of BMP signaling in AGM hematopoiesis.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 4 agent sets
Platform:
GPL1261
Series:
GSE62517
8 Samples
Download data: CEL
3.
Full record GDS5806

FLT3/ITD-SmoM2 acute myeloid leukemia model: sorted bone marrow cells

Analysis of KSL and GMP cells isolated from bone marrow of Flt3/ITD-SmoM2 transgenics at around 3 months of age when they developed leukemia. Wild-type and FLT3/ITD littermates of the FLT3/ITD-SmoM2 animals were also examined. Results provide insight into the role of SmoM2 in leukemic progression.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 cell type, 3 genotype/variation sets
Platform:
GPL1261
Series:
GSE67134
6 Samples
Download data: CEL, CHP
4.
Full record GDS5678

Anti-VEGF and Anti-Notch treatment effect on U87 glioblastoma xenograft tumors [Mouse430_2]

Analysis of U87 human xenograft tumors (in BALB/c SCID mouse host) treated with antiangiogenic agents bevacizumab (anti-VEGF) and dibenzazepine (anti-Notch). The tumors include mouse host stroma. Results, together with those from GDS5672, provide insight into molecular basis of tumor angiogenesis.
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by array, transformed count, 3 agent sets
Platform:
GPL1261
Series:
GSE39413
14 Samples
Download data: CEL
5.
Full record GDS5663

Pulmonary dendritic cell subsets

Analysis of four dendritic cell (DC) subsets purified from the lungs of C57BL/6 males following inhalation of LPS/OVA. The four subsets represent conventional DCs (cDCs) and monocyte-derived DCs (moDCs). Results provide insight into molecular profiles that would discriminate between cDCs and moDCs.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 4 cell type, 2 other sets
Platform:
GPL1261
Series:
GSE64896
12 Samples
Download data: CEL, CHP
6.
Full record GDS5660

Early postnatal skeletal muscle stem cells: time course

Analysis of myogenic stem cells called satellite cells (mSCs) FACS-sorted from the trunk of Pax3GFP/+ mice at postnatal days 1, 12, and 28, a period when most mSCs are in proliferation and quiescence states. Results provide insight into molecular basis of early postnatal skeletal muscle development.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 age, 2 tissue sets
Platform:
GPL1261
Series:
GSE65927
11 Samples
Download data: CEL
DataSet
Accession:
GDS5660
ID:
5660
7.
Full record GDS5658

Retinoid X receptor activation effect on stimulated RAW264.7 cells

Analysis of RAW 264.7 macrophages pre-treated with vitamin A derivative 9cis-retinoic acid (9cRA), then stimulated with bacterial LPS or viral mimetic polyI:C. 9cRA is a high affinity ligand for retinoid X receptor (RXR). Results provide insight into the role of RXR in host antiviral response.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 protocol, 3 stress sets
Platform:
GPL1261
Series:
GSE62107
6 Samples
Download data: CEL, CHP
8.
Full record GDS5656

Forkhead box O 1,3,4 muscle-specific knockout effect on fasted gastrocnemius muscle

Analysis of gastrocnemius muscle from starved males with muscle-specific deletion of Forkhead Box O transcription factors 1, 3 and 4 (FoxO1,3,4-/-). Results provide insight into the collective roles of FoxOs during muscle atrophy.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation, 2 stress sets
Platform:
GPL1261
Series:
GSE52667
4 Samples
Download data: CEL
9.
Full record GDS5644

Transforming growth factor, beta receptor II knockout effect on embryonic posterior palate

Analysis of posterior portions of the palate from E15.5 embryos with an epithelial cell-specific conditional inactivation of Transforming growth factor, beta receptor II (Tgfbr2). Results, together with those from GDS4921, provide insight into the role of TGFβ signaling in soft palate development.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE46211
12 Samples
Download data: CEL
10.
Full record GDS5642

Tendon development: embryonic limb tendon cells

Analysis of tendon cells isolated by FACS from forelimbs of embryonic day 11.5, E12.5 and E14.5 scleraxis (Scx)-GFP embryos. Basic helix-loop-helix transcription factor Scx is a specific tendon and ligament marker. Results provide insight into molecular pathways involved in tendon development.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 age sets
Platform:
GPL1261
Series:
GSE54207
9 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS5642
ID:
5642
11.
Full record GDS5640

Double-knockout p53/PRKDC model of B cell acute lymphoblastic leukemia: leukemic blasts

Analysis of leukemic blasts from p53/Prkdc double-knockout mutants that spontaneously develop early B cell acute lymphoblastic leukemia (B-ALL). Results provide insight into molecular mechanisms underlying high-risk B-ALL.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 cell type, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE56345
9 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS5640
ID:
5640
12.
Full record GDS5634

High multiplicity mycobacterial infections of macrophages in vitro

Analysis of macrophage cell line J774A.1 infected with pathogenic mycobacteria BCG and H37Ra and non-pathogenic M. smegmatis under high multiplicity of infection (MOI = 50). Results provide insight into the molecular response of macrophage host cells to pathogenic and non-pathogenic mycobacteria.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 4 infection, 4 species sets
Platform:
GPL1261
Series:
GSE45675
4 Samples
Download data: CEL, CHP
13.
Full record GDS5624

Epigenetic modifying reagents effect on a progressive hearing loss model: whole cochlea

Analysis of cochlea from 4 wk old DBA/2J males (a model of progressive hearing loss) injected for 8 wks with a combination of epigenetic modifiers l-methionine and valproic acid. Results provide insight into the effect of epigenetic modifications on the molecular mechanisms underlying hearing loss.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 age, 3 protocol sets
Platform:
GPL1261
Series:
GSE62173
16 Samples
Download data: CEL
14.
Full record GDS5609

Notch ligand delta-like 4 effect on interleukin 10-secreting T helper 1 cells

Analysis of IL-10-secreting and -nonsecreting T helper 1 (Th1) cells stimulated with Notch ligand Delta-like 4. The Notch pathway is a major driver of IL-10 production in Th1 cells. Results provide insight into the molecular basis of Notch-mediated IL-10 induction in Th1 cells.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 2 cell type sets
Platform:
GPL1261
Series:
GSE57417
4 Samples
Download data: CEL, CHP
15.
Full record GDS5608

NF-κB subunit p65 depletion effect on Ras-induced transformation model: cultured embryonic fibroblasts

Analysis of p65+/+Ras and p65-/-Ras cells generated by infecting NF-κB subunit p65+/+ and p65-/- MEFs with pBabe-HRASG12V. Post-injection of the Ras cells into SCID mice, RasT tumors were removed, reconstituted in culture and examined. Results provide insight into role of NF-κB in tumorigenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 cell line, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE59545
4 Samples
Download data: CEL, DCP, TXT
16.
Full record GDS5605

Listeria monocytogenes infection effect on transcriptional repressor BLIMP1-deficient macrophage

Analysis of B lymphocyte-induced maturation protein 1 (BLIMP1) conditional knockout macrophages infected with Listeria monocytogenes for 2 hr. Results provide insight into BLIMP1-mediated regulatory mechanisms in macrophages in early host defense against intracellular bacteria.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 genotype/variation, 2 infection sets
Platform:
GPL1261
Series:
GSE53145
12 Samples
Download data: CEL
17.
Full record GDS5602

Transcription factor Inhibitor of differentiation 3 knockout effect on invariant natural killer T cells: developmental time course

Analysis of stage 1 (Tet+CD24-CD44-NK1.1-) and stage 2 (Tet+CD24-CD44+NK1.1-) invariant natural killer T (iNKT) cells FACS-sorted from inhibitor of differentiation 3 (Id3) knockout thymus. Results provide insight into the role of transcriptional regulator ID3 during iNKT cell maturation in thymus.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 cell type, 2 development stage, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE50933
10 Samples
Download data: CEL
18.
Full record GDS5601

Nanoemulsion adjuvant W805EC effect on JAWS II dendritic cells: time course

Analysis of JAWS II DCs incubated with nanoemulsion (NE) adjuvant W805EC for up to 24 hrs. W805EC is an oil-in-water emulsion with nanodroplets similar in size to many viruses infecting the nasal mucosa. Results provide insight into the molecular basis of the adjuvant activity of W805EC NE in DCs.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 5 protocol, 2 time sets
Platform:
GPL1261
Series:
GSE51804
10 Samples
Download data: CEL
19.
Full record GDS5519

5-azacytidine effect on mesenchymal progenitor cell line

Analysis of C2C12 mesenchymal progenitor cells treated with 5-azacytidine (5AC). 5AC is a DNA methylation inhibitor and induces genomic demethylation. Results provide insight into the role of DNA demethylation on skeletal myotube maturation.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL1261
Series:
GSE30192
6 Samples
Download data: CEL
DataSet
Accession:
GDS5519
ID:
5519
20.
Full record GDS5468

Interleukin-33 effect on dual-specificity phosphatase 5-deficient bone marrow derived eosinophils

Analysis of BM-derived eosinophils isolated from dual-specificity phosphatase 5-deficient mice and stimulated with IL-33. DUSP5 is a growth factor‐inducible phosphatase preferentially expressed in immune cells. Results provide insight into the role of DUSP5 in IL-33 signaling in eosinophils.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 agent, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE62999
20 Samples
Download data: CEL
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