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Links from GEO DataSets

Items: 1 to 20 of 21

1.
Full record GDS5261

Interleukin 4, interleukin 13 and tumor necrosis factor-α effect on Matrigel-cultured IMR-90 lung fibroblast cells

Analysis of IMR-90 cells cultured on Matrigel and treated with IL-4, IL-13 or TNFα. Type 2 inflammatory processes mediated by IL-4 and IL-13 are implicated in pathologic lung fibrogenesis. Results provide insight into molecular mechanisms underlying the onset and maintenance of pulmonary fibrosis.
Organism:
Homo sapiens
Type:
Expression profiling by array, log2 ratio, 4 agent sets
Platform:
GPL6480
Series:
GSE47542
12 Samples
Download data: TXT
DataSet
Accession:
GDS5261
ID:
5261
2.
Full record GDS6010

Influenza virus H5N1 infection of U251 astrocyte cell line: time course

Analysis of U251 astrocyte cells infected with the influenza H5N1 virus for up to 24 hours. Results provide insight into the immune response of astrocytes to H5N1 infection.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 infection, 3 time sets
Platform:
GPL6480
Series:
GSE66597
18 Samples
Download data: TXT
3.
Full record GDS5639

Phorbol myristate acetate plus ionomycin activation effect on primary T lymphoblasts and their exosomes

Analysis of primary T lymphoblasts and derived exosomes after activation with PMA plus ionomycin. Exosomes contain specific RNA species and can be functionally transferred to recipient cells. Results provide insight into molecular mechanisms underlying the selective sorting of RNA into exosomes.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 cell type, 2 protocol sets
Platform:
GPL6480
Series:
GSE50971
8 Samples
Download data: TXT
4.
Full record GDS5498

Arsenic effect on lung epithelial cell line

Analysis of BEAS-2B lung epithelial cells treated with 2.5 uM arsenic trioxide for 6 months. Chronic arsenic exposure increases lung cancer risk. Results provide insight into the molecular mechanisms underlying lung carcinogenesis associated with arsenic exposure.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent sets
Platform:
GPL6480
Series:
GSE33520
7 Samples
Download data: TXT
5.
Full record GDS5416

Supercritical rosemary extract effect on SW620 colon cancer cells: dose response

Analysis of adenocarcinoma derived-SW620 colon cancer cells treated with supercritical rosemary extract (RE-2) at doses of 30, 60 and 100 μg/mL. RE contains carnosic acid and carnosol (diterpenes) and essential oils. Results provide insight into the molecular basis of RE's anticancer effects.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 4 dose sets
Platform:
GPL6480
Series:
GSE56496
8 Samples
Download data: TXT
6.
Full record GDS5371

Atypical ubiquitin ligase RNF31 depletion effect on ER-alpha positive breast cancer cell line

Analysis of MCF-7 breast cancer cells depleted for RNF31. RNF31 is an atypical E3 ubiquitin ligase. MCF-7 is an estrogen receptor (ER) alpha positive cell line. Results provide insight into the role of RNF31 in the ER-alpha stimulated proliferation of breast cancer cells.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 protocol sets
Platform:
GPL6480
Series:
GSE46010
7 Samples
Download data: TXT
7.
Full record GDS5368

N-terminal truncated GATA1-mutant effect on fetal CD34+ hematopoietic stem and progenitor cells: time course

Analysis of fetal CD34+ HSPCs expressing N-terminal truncated GATA1-mutant (GATA1s) during myeloid differentiation for 4 and 14 days. GATA1s mutations are associated with transient leukemia (TL)- in Down syndrome neonates. Results provide insight into the role of GATA1s in TL pathogenesis.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 protocol, 3 time sets
Platform:
GPL6480
Series:
GSE56332
9 Samples
Download data: TXT
8.
Full record GDS5314

Placental CD14+ macrophage-derived multinucleated giant cells

Analysis of placental multinucleated giant cells (MGCs) obtained from at-term placental CD14+ macrophages cultured in DMEM-F12 containing 10% FCS and antibiotics for 9 days. Results provide insight into molecular mechanisms underlying the maturation of macrophages into MGCs.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 cell type sets
Platform:
GPL6480
Series:
GSE38747
12 Samples
Download data: TXT
DataSet
Accession:
GDS5314
ID:
5314
9.
Full record GDS5292

TRPV1 activation effect on epithelial cell line

Analyis of epi 4 gingival cells treated with capsaicin, the pungent compound present in red chilies. Capsaicin is an activator of transient receptor potential cation channel subfamily V member 1 (TRPV1). Results provide insight into the function of TRPV1 in gingival cells.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL6480
Series:
GSE57759
8 Samples
Download data: TXT
10.
Full record GDS5262

Interleukin 4, interleukin 13 and tumor necrosis factor-α effect on plastic-cultured IMR-90 lung fibroblast cells

Analysis of IMR-90 cells cultured on plastic and treated with IL-4, IL-13 or TNFα. Type 2 inflammatory processes mediated by IL-4 and IL-13 are implicated in pathologic lung fibrogenesis. Results provide insight into molecular mechanisms underlying the onset and maintenance of pulmonary fibrosis.
Organism:
Homo sapiens
Type:
Expression profiling by array, log2 ratio, 4 agent sets
Platform:
GPL6480
Series:
GSE47542
12 Samples
Download data: TXT
DataSet
Accession:
GDS5262
ID:
5262
11.
Full record GDS5230

miR-193b overexpression effect on pancreatic cell line

Analysis of MIA PaCa-2 pancreatic cancer cells overexpressing miR-193b. Aberrant expression of microRNAs occurs in various cancers, including pancreatic cancer. Results identify target genes of miR-193b.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 protocol sets
Platform:
GPL6480
Series:
GSE25215
4 Samples
Download data: TXT
DataSet
Accession:
GDS5230
ID:
5230
12.
Full record GDS5206

Silica nanoparticle effect on lung adenocarcinoma epithelial A549 cells

Analysis of A549 cells treated with SiO2 NPs (diameters of 9nm and 18nm) and examined after 3hr and 22hr recovery times. Coated nanomaterials (e.g., SiO2 NPs) agglomerate less and are, thus, more easily inhalable. Results provide molecular insight into molecular basis of nanotoxicological effects.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 4 agent, 2 time sets
Platform:
GPL6480
Series:
GSE53700
18 Samples
Download data: TXT
13.
Full record GDS5177

Kruppel-like factor 9 overexpression effect on keratinocyte: time course

Analysis of primary neonatal foreskin keratinocytes overexpressing Kruppel-like factor 9 (KLF9) for up to 7 days. KLF9 is a transcription factor that binds to GC box elements. Results identify downstream targets of KLF9.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 protocol, 3 time sets
Platform:
GPL6480
Series:
GSE36014
6 Samples
Download data: TXT
14.
Full record GDS5176

Epidermis at various time points during the day

Analysis of epidermal samples from 20 individuals obtained at 9:30 am, 2:30 pm and 7:30 pm. Results identify transcripts that exhibit time-dependent expression in the epidermis.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 20 individual, 3 time sets
Platform:
GPL6480
Series:
GSE35635
57 Samples
Download data: TXT
15.
Full record GDS5037

Severe asthma: bronchial epithelial cell

Analysis of bronchial epithelial cells from patients with severe asthma. Results provide insight into the molecular mechanisms underlying the development of severe asthma.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 disease state, 2 gender sets
Platform:
GPL6480
Series:
GSE43696
108 Samples
Download data: TXT
16.
Full record GDS5021

Placenta response to maternal choline intake throughout the third trimester of pregnancy: dose response

Analysis of placenta retrieved at delivery from healthy women who consumed up to 930mg choline/day throughout their third trimester of pregnancy. Results provide insight into the molecular mechanisms underlying the benefits of maternal choline supplementation on placental function.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 dose, 2 gender, 2 other sets
Platform:
GPL6480
Series:
GSE39290
12 Samples
Download data: TXT
DataSet
Accession:
GDS5021
ID:
5021
17.
Full record GDS4807

IL-17C effect on keratinocytes: time course

Analysis of keratinocytes treated with Interleukin 17C (IL-17C) for 3 and 24 hours. IL-17C is induced in epithelia by bacterial challenge and inflammatory stimuli and upregulated in psoriatic skin lesions. Results provide insight into the role of IL-17C in the innate epithelial immune response.
Organism:
Homo sapiens
Type:
Expression profiling by array, log2 ratio, 2 agent, 2 time sets
Platform:
GPL6480
Series:
GSE32620
16 Samples
Download data: TXT
DataSet
Accession:
GDS4807
ID:
4807
18.
Full record GDS3946

Dexamethasone effect on cultured airway smooth muscle cells: time course

Analysis of airway smooth muscle (ASM) cells treated with glucocorticoid (GC) dexamethasone for 4 or 24h. GCs are used to treat asthma, exerting their therapeutic effects in part through modulating ASM structure/function. Results provide insight into molecular mechanisms underlying GC action in ASM.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent, 3 time sets
Platform:
GPL6480
Series:
GSE34313
10 Samples
Download data: TXT
19.
Full record GDS3897

Red meat consumption effect on inflammatory bowel disease: colon

Analysis of colon biopsies from inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) subjects. Colon biopsies also examined from 12 of these subjects (6 IBD, 6 IBS) after a 7-day diet high in red meat (300g/day). Results provide insight into molecular basis of IBD pathophysiology.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state, 2 gender, 32 individual, 2 protocol sets
Platform:
GPL6480
Series:
GSE25220
44 Samples
Download data: GPR
DataSet
Accession:
GDS3897
ID:
3897
20.
Full record GDS3796

Alkylphospholipids effect on HaCaT keratinocytes

Analysis of HaCaT keratinocytes treated with alkylphospholipids (APLs) Ino-C2-PAF, Glc-PAF, and edelfosine. APLs interfere with a variety of key enzymes implicated in cell growth, motility, invasion, and apoptosis. Results provide insight into mechanism of action of APLs.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 4 agent sets
Platform:
GPL6480
Series:
GSE20722
12 Samples
Download data: TXT
DataSet
Accession:
GDS3796
ID:
3796
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