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Links from GEO DataSets

Items: 1 to 20 of 364

1.
Full record GDS5401

Rheumatoid arthritis and osteoarthritis: synovial tissues (Berlin dataset)

Analysis of synovial tissues from patients with rheumatoid arthritis or osteoarthritis. Results used to generate rule-based classifiers to distinguish patients with rheumatoid arthritis from those with osteoarthritis.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 disease state sets
Platform:
GPL96
Series:
GSE55235
30 Samples
Download data: CEL
2.
Full record GDS5407

CD40 activation effect on CD19-positive B cells

Analysis of peripheral blood-purified CD19-positive B cells activated with CD40. CD40 is a potent activation stimulus for the induction of B cell-mediated antigen presentation and cytokine production. Results provide insight into molecular mechanisms underlying B cell activation via CD40.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 4 individual, 2 protocol sets
Platform:
GPL96
Series:
GSE54017
8 Samples
Download data: CEL
DataSet
Accession:
GDS5407
ID:
5407
3.
Full record GDS5403

Rheumatoid arthritis and osteoarthritis: synovial tissues (Jena dataset)

Analysis of synovial tissues from patients with rheumatoid arthritis or osteoarthritis. Results used to generate rule-based classifiers to distinguish patients with rheumatoid arthritis from those with osteoarthritis.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 disease state sets
Platform:
GPL96
Series:
GSE55457
33 Samples
Download data: CEL
4.
Full record GDS5402

Rheumatoid arthritis and osteoarthritis: synovial tissues (Leipzig dataset)

Analysis of synovial tissues from patients with rheumatoid arthritis or osteoarthritis. Results used to generate rule-based classifiers to distinguish patients with rheumatoid arthritis from those with osteoarthritis.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL96
Series:
GSE55584
16 Samples
Download data: CEL
5.
Full record GDS5245

Allergic asthma: alveolar macrophage

Comparison of alvelolar macrophages (AMs) of allergic asthma (AA) patients and healthy subjects. AMs are the main immune cells in the airway lumen and are in direct contact with exogenous agents. Results provide insight into the differences between the AMs of AA patients and healthy individuals.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state sets
Platform:
GPL96
Series:
GSE22528
10 Samples
Download data: CEL
6.
Full record GDS5026

17β-estradiol effect on breast adenocarcinoma cells deficient in extracellular signal-regulated kinase 5

Analysis of MCF-7 breast cancer (BC) cells depleted for ERK5 then treated with 17β-estradiol. Increased kinase activity is associated with a poorer outcome for BC patients. Results provide insight into the interplay between estrogen receptor and protein kinase pathways to regulate BC aggressiveness
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 2 genotype/variation sets
Platform:
GPL96
Series:
GSE53394
8 Samples
Download data: CEL
7.
Full record GDS4995

Scleroderma-associated interstitial lung disease patients: pulmonary fibroblasts

Analysis of lung fibroblasts isolated from biopsies, taken at the time of diagnosis, from patients with well-defined pulmonary fibrosis associated with systemic sclerosis (SSc-ILD). Results provide insight into the molecular mechanisms underlying the fibrotic fibroblast phenotype in SSc-ILD.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 disease state sets
Platform:
GPL96
Series:
GSE40839
21 Samples
Download data: CEL
8.
Full record GDS4844

Cystic fibrosis: rectal epithelia

Analysis of rectal mucosal epithelia from cystic fibrosis patients homozygous for the three-base-pair deletion c.1521_1523delCTT (p.Phe508del, F508del) in the cystic fibrosis transmembrane conductance regulator (CFTR). Results provide insight into molecular mechanisms underlying CF.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL96
Series:
GSE15568
29 Samples
Download data: CEL
9.
Full record GDS4560

Oral squamous cell carcinoma-derived cell lines

Analysis of oral squamous cell carcinoma (OSCC)-derived cell lines. OSCC is a lethal disease with early death typically occurring as a result of local invasion and regional lymph node metastases. Results provide insight the molecular mechanisms underlying OSCC.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 9 cell line sets
Platform:
GPL96
Series:
GSE31853
9 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS4560
ID:
4560
10.
Full record GDS4541

Hungington's disease: whole blood

Analysis of whole blood from Huntington’s disease (HD) patients and age- and sex-matched healthy controls. To date, a robust and clinically useful blood test for HD has not been developed. Results provide insight into blood biomarkers for HD activity.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 12 age, 2 disease state, 2 gender, 14 individual sets
Platform:
GPL96
Series:
GSE24250
14 Samples
Download data: CEL
11.
Full record GDS4515

Microsatellite-unstable colorectal cancer

Analysis of colorectal adenocarcinomas with microsatellite instability (MSI CRCs). MSI, caused by defects in the mismatch repair system, is observed in a subset of CRCs. Results provide insight into molecular mechanisms contributing to MSI CRC development.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state sets
Platform:
GPL96
Series:
GSE24514
49 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS4515
ID:
4515
12.
Full record GDS4501

Acute myeloid leukemia with mutated nucleophosmin: bone marrow blasts (test set)

Analysis of AML blasts displaying aberrant cytoplasmic localization of nucleophosmin (NPMc+ AML) but negative for AML-associated chromosomal translocations. Results provide insight into the validity of the putative predictors of NPM status identified by the training set.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL96
Series:
GSE34860
39 Samples
Download data: CEL
DataSet
Accession:
GDS4501
ID:
4501
13.
Full record GDS4500

Acute myeloid leukemia with mutated nucleophosmin: bone marrow blasts (training set)

Analysis of AML blasts displaying aberrant cytoplasmic localization of nucleophosmin (NPMc+ AML) but negative for AML-associated chromosomal translocations. Results provide insight into putative predictors of NPM status.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL96
Series:
GSE34860
39 Samples
Download data: CEL
DataSet
Accession:
GDS4500
ID:
4500
14.
Full record GDS4418

Allergic asthma: bronchial biopsies

Analysis of bronchial biopsies from allergic asthma (AA) subjects. These results, together with those from GDS4417 (a study with similar specimen collection procedures, but different subjects, GeneChips, data processing), provide insight into molecular mechanisms underlying AA pathophysiology.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state sets
Platform:
GPL96
Series:
GSE41649
8 Samples
Download data: CEL
DataSet
Accession:
GDS4418
ID:
4418
15.
Full record GDS4209

Anti-CD47 antibody dimer MABL (S-S diabody) effect on leukemia cell line: time course

Temporal analysis of MOLT-4 leukemia cells treated with 10 ug/mL anti-CD47 dimer MABL (S-S diabody). Cell surface antigen CD47 ligation induces apoptosis in B-chronic lymphocytic leukemia. Results provide insight into the molecular mechanism of CD47-mediated apoptosis in lymphoid malignant cells.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 5 time sets
Platform:
GPL96
Series:
GSE16494
10 Samples
Download data: CEL
DataSet
Accession:
GDS4209
ID:
4209
16.
Full record GDS4185

Systemic Lupus Erythematosus: mononuclear cells

Analysis of freshly isolated lymphocyte (CD4+ T cells and CD19+ B cells) and CD33+ myeloid subsets from the blood of Systemic Lupus Erythematosus (SLE) patients. Results provide insight into the molecular mechanisms underlying SLE pathogenesis.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 cell type, 2 disease state sets
Platform:
GPL96
Series:
GSE10325
67 Samples
Download data: CEL
17.
Full record GDS4167

Chronic lymphocytic leukemia: peripheral blood B cells (HG-U133A)

Analysis of peripheral blood B cells isolated from 41 untreated chronic lymphocytic leukemia (CLL) patients and 11 age-matched control subjects. B-cell CLL is the most common type of leukemia, mainly affecting adults. Results provide insight into molecular mechanisms underlying CLL pathogenesis.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state sets
Platform:
GPL96
Series:
GSE22529
52 Samples
Download data: CEL
18.
Full record GDS4145

Subcutaneous Interferon-beta-1b treatment in relapsing-remitting multiple sclerosis (U133 A): peripheral mononuclear blood cells

Temporal analysis of PBMCs collected from 25 German relapsing-remitting multiple sclerosis patients treated with recombinant interferon-beta-1b (rIFN-β-1b, 250 µg every other day) for 2 years. Results provide insight into molecular mechanisms of IFN-b action.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 gender, 5 time sets
Platform:
GPL96
Series:
GSE24427
125 Samples
Download data: CEL
19.
Full record GDS4109

Recurrent and non-recurrent prostate cancer primary tumors

Analysis of prostate cancer primary tumors of known disease recurrence status. Results provide insight into the molecular mechanisms underlying recurrent and non-recurrent prostate cancer primary tumors.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL96
Series:
GSE25136
79 Samples
Download data: CEL
20.
Full record GDS4088

Variable breast cancer tumor sample collection methods

Analysis of breast tumor samples preserved using 2 different RNA stabilization methods (RNAlater or snap freezing) up to 3 hours post tumor excision. Results provide insight into the effects of tissue handling on RNA integrity and microarray measurements from resected breast cancers.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 11 individual, 35 other, 2 protocol, 6 time sets
Platform:
GPL96
Series:
GSE25011
86 Samples
Download data: CEL
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