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Links from GEO DataSets

Items: 16

1.
Full record GDS5818

Normal liver developmental stages: embryonic and postnatal

Analysis of hepatoblasts, immature hepatocytes and hepatocytes from livers at different developmental timepoints (embryonic day 14, embryonic day 18, post-natal day 5, post-natal day 56). Results provide insight into molecular mechanisms underlying normal liver development.
Organism:
Mus musculus
Type:
Expression profiling by array, log2 ratio, 4 age, 3 cell type, 2 development stage sets
Platform:
GPL7202
Series:
GSE65063
11 Samples
Download data: TXT
2.
Full record GDS6016

Transcription factor engrailed-2 loss-of-function model of autism spectrum disorder: hippocampus

Analysis of hippocampal samples from engrailed-2 (En2) mutant adults. The En2-/- animals are a model for autism spectrum disorder (ASD). The hippocampus is a brain area profoundly affected in ASD patients. Results provide insight into molecular mechanisms underlying ASD-related neuropathology.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 genotype/variation sets
Platform:
GPL7202
Series:
GSE51612
6 Samples
Download data: TXT
3.
Full record GDS5666

4T1 breast cancer model: metastatic sub-populations

Analysis of parental mammary tumor cell line 4T1-derived metastatic populations isolated from liver, lung or bone. Results provide insight into molecular mechanisms associated with the different metastatic breast cancer sub-populations.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 5 cell type sets
Platform:
GPL7202
Series:
GSE62598
15 Samples
Download data: TXT
4.
Full record GDS5629

Citrobacter rodentium infection of interleukin-10 deficient colon

Analysis of whole colon tissue two weeks after C. rodentium infection of IL-10-deficient C57BL/6 females. C. rodentium is a mucosal pathogen that colonizes the colon causing transient mucosal inflammation. Results provide insight into the role of IL-10 in the colonic response to infection.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation, 2 infection sets
Platform:
GPL7202
Series:
GSE55812
4 Samples
Download data: TXT
5.
Full record GDS5612

Sirtuin-1 activator resveratrol effect on adult secondary neurospheres

Analysis of adult secondary neurospheres derived from hippocampal neural stem cells/neural progenitor cells and treated with resveratrol, an activator of NAD-dependent histone deacetylase Sirtuin-1 (Sirt1). Results provide insight into the role of Sirt1 in adult hippocampal neurogenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 agent sets
Platform:
GPL7202
Series:
GSE39551
4 Samples
Download data: TXT
DataSet
Accession:
GDS5612
ID:
5612
6.
Full record GDS5611

Sirtuin-1 deficiency effect on adult secondary neurospheres

Analysis of adult secondary neurospheres derived from hippocampal neural stem cells/neural progenitor cells of sirtuin-1 knockout mice. Sirt1 is a nicotinamide adenine dinucleotide (NAD)-dependent histone deacetylase. Results provide insight into the role of Sirt1 in adult hippocampal neurogenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 genotype/variation sets
Platform:
GPL7202
Series:
GSE39551
4 Samples
Download data: TXT
DataSet
Accession:
GDS5611
ID:
5611
7.
Full record GDS5343

T helper type 9 cells stimulated with anti-CD3 antibody

Analysis of naive CD4+ T cells cultured under T helper type 9 (Th9) conditions for 5 days and activated with anti-CD3 antibody. Th9 cells are a subpopulation of CD4+ effector T cells that secrete high levels of interleukin-9. Results provide insight into the molecular basis of the Th9 phenotype.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 protocol sets
Platform:
GPL7202
Series:
GSE44937
6 Samples
Download data: TXT
8.
Full record GDS5291

T helper type 9 cells

Analysis of naive CD4+ T cells cultured under T helper type 9 (Th9), Th2, or Treg conditions for 5 days. Th9 cells are a subpopulation of CD4+ effector T cells that secrete high levels of interleukin-9. Results provide insight into the molecular basis of the Th9 phenotype.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 cell type sets
Platform:
GPL7202
Series:
GSE44937
9 Samples
Download data: TXT
9.
Full record GDS5264

High-fat diet effect on obesity-resistant NAG-1 transgenics: colon epithelium

Analysis of colon epithelium from NAG-1 (NSAID-activated gene-1) transgenics and wild-type C57BL/6J animals fed a high-fat diet for 20wk. The NAG-1 transgenics did not gain weight as their wild-type counterparts did. Results provide insight into the molecular impact of obesity on colonic epithelium.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 genotype/variation, 2 protocol sets
Platform:
GPL7202
Series:
GSE46843
11 Samples
Download data: TXT
10.
Full record GDS5258

Chronic, low level drug exposure effect on obese liver

Analysis of liver from ob/ob obese males given water with 1 mg/L each of 11 drugs during 4 months. Contamination of drinking water with these drugs may have harmful effects on health. Results provide insight into mechanisms underlying obese liver responses to water-borne drug contamination.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 agent, 2 genotype/variation sets
Platform:
GPL7202
Series:
GSE49195
24 Samples
Download data: TXT
DataSet
Accession:
GDS5258
ID:
5258
11.
Full record GDS5241

Transcription factor engrailed-2 loss-of-function model of autism spectrum disorder: cerebellum

Analysis of cerebellar samples from engrailed-2 (En2) mutant adults. The En2-/- animals are a model for autism spectrum disorder (ASD). The cerebellum is a brain area profoundly affected in ASD patients. Results provide insight into molecular mechanisms underlying ASD-related neuropathology.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 genotype/variation sets
Platform:
GPL7202
Series:
GSE51612
6 Samples
Download data: TXT
12.
Full record GDS5228

Hoxa1 deficiency effect on rhombomere regions 3 to 5

Analysis of rhombomere regions 3 to 5 from embryos lacking the homeobox protein Hoxa1. Hoxa1 is necessary for the development of the brainstem, inner ear and heart. Results identify the role of Hoxa1 during embryogenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 genotype/variation sets
Platform:
GPL7202
Series:
GSE25868
8 Samples
Download data: TXT
13.
Full record GDS3986

High-fat dietary restriction effect on epididymal white adipose tissue

Analysis of epididymal WAT from C57BL/6J adult males adapted to a high-fat diet for 3 wks, then fed a high-fat diet on an ad-libitum basis (HF-AL) or on a restricted basis (HF-DR) for 12 wks. Results provide insight into molecular mechanisms underlying improved metabolic health induced by HF-DR.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 protocol sets
Platform:
GPL7202
Series:
GSE27213
36 Samples
Download data: TXT
DataSet
Accession:
GDS3986
ID:
3986
14.
Full record GDS3922

Spatial and temporal development of mammalian salivary glands

Analysis of highly localized regions of salivary gland epithelia from 12.5-, 13.5-, 14-, and 15-day-old ICR embryos. Development of mouse submandibular salivary gland begins at E11.5. Results provide insight into molecular mechanisms underlying salivary gland development and differentiation.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 4 age, 6 tissue sets
Platform:
GPL7202
Series:
GSE22828
84 Samples
Download data: TXT
15.
Full record GDS3890

Interstrain differences in the liver effects of trichloroethylene

Analysis of liver from multiple inbred strains 24hr after trichloroethylene (TCE) treatment. TCE is a widely used industrial chemical and a ubiquitous environmental contaminant. Results provide insight into the molecular mechanisms underlying interstrain differences in liver effects of TCE.
Organism:
Mus musculus
Type:
Expression profiling by array, log2 ratio, 2 agent, 16 strain sets
Platform:
GPL7202
Series:
GSE24278
94 Samples
Download data: TXT
16.
Full record GDS3666

SIRT1 deficiency effect on the liver

Analysis of liver deficient for SIRT1. SIRT1, a NAD+-dependent protein deacetylase, is an important regulator of energy homeostasis in response to nutrient availability. Results provide insight into the role of hepatic SIRT1 in fatty acid metabolsim.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL7202
Series:
GSE14921
6 Samples
Download data: TIFF, TXT
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