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Items: 2

1.
Full record GDS1234

Fibroblast growth factor receptor 3 K650E mutation for type II thanatophoric dysplasia

Analysis of PC12 cells expressing fibroblast growth factor receptor 3 (FGFR3) K650E mutant responsible for thanatophoric dysplasia (TD) type II. Mutant receptor expressed as a chimera of FGFR3 and platelet derived growth factor receptor. Results provide insight into TD type II pathogenesis.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL85
Series:
GSE2606
8 Samples
Download data
DataSet
Accession:
GDS1234
ID:
1234
2.

Gene expressing profiling of PC12 cells expressing the FGFR3 mutation responsible for thanatophoric dysplasia type II

(Submitter supplied) To investigate signaling pathways activated by FGFR3 mutations through an analysis of altered expression of downstream transcriptional targets, we performed gene expression profiling of stably transfected inducible PC12 cells expressing a chimeric receptor (PFR3) consisting of the extracellular domain of human platelet derived growth factor receptor (PDGFR) and the transmembrane and intracellular domains of human FGFR3 under the control of the zinc inducible metalliothionein promoter. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS1234
Platform:
GPL85
8 Samples
Download data
Series
Accession:
GSE2606
ID:
200002606

Supplemental Content

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