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Links from GEO DataSets

Items: 20

1.
Full record GDS1767

Zucker diabetic fatty model of type 2 diabetes: various insulin-sensitive tissues

Analysis of adipose, skeletal muscle, and liver tissues of Zucker diabetic fatty animals at pre-diabetic and diabetic stages. ZDF animals have a mutated leptin receptor. Results provide insight into the molecular mechanisms responsible for insulin resistance and progression to type 2 diabetes.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, log ratio, 2 age, 3 tissue sets
Platform:
GPL1002
Series:
GSE1080
24 Samples
Download data
DataSet
Accession:
GDS1767
ID:
1767
2.

Zucker diabetic fatty (ZDF)/Zucker lean control (ZLC) comparisons

(Submitter supplied) Gene expression profiles in tissues of Zucker diabetic fatty (ZDF) rats compared with age matched Zucker lean control (ZLC) rats. Keywords: other
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS1767
Platform:
GPL1002
24 Samples
Download data
Series
Accession:
GSE1080
ID:
200001080
3.

Molecular studies on sex-different control of the hepatic metabolism in relations to insulin sensitivity

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL6528
8 Samples
Download data: GPR
Series
Accession:
GSE23810
ID:
200023810
4.

Molecular studies on sex-different control of the hepatic metabolism in relations to insulin sensitivity (set 2)

(Submitter supplied) In this study we have analyzed gene expression and metabolite levels in the livers of male and female Zucker diabetic fatty (ZDF) rats. We speculated that the sex different development of diabetes in the ZDF animals presents the opportunity to relate gender to diabetes (since only males become diabetic on normal diet). In this model one can search for parameters that distinguish females fed normal diet compared to high fat diet (i.e. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL6528
4 Samples
Download data: GPR
Series
Accession:
GSE23809
ID:
200023809
5.

Molecular studies on sex-different control of the hepatic metabolism in relations to insulin sensitivity (set 1)

(Submitter supplied) In this study we have analyzed gene expression and metabolite levels in the livers of male and female Zucker diabetic fatty (ZDF) rats. We speculated that the sex different development of diabetes in the ZDF animals presents the opportunity to relate gender to diabetes (since only males become diabetic on normal diet). In this model one can search for parameters that distinguish females fed normal diet compared to high fat diet (i.e. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL6528
4 Samples
Download data: GPR
Series
Accession:
GSE23808
ID:
200023808
6.

Reduced expression of mitochondrial oxidative metabolism genes in skeletal muscle of women with PCOS

(Submitter supplied) Recently, abnormalities in mitochondrial oxidative phosphorylation (OXPHOS) have been implicated in the pathogenesis of skeletal muscle insulin resistance in type 2 diabetes. In the present study, we hypothesized that decreased expression of OXPHOS genes could be of similar importance for insulin resistance in the polycystic ovary syndrome (PCOS). Using the HG-U133 Plus 2.0 expression array from Affymetrix, we analyzed gene expression in skeletal muscle from obese women with PCOS (n=16) and age- and body mass index-matched control women (n=13) metabolically characterized by euglycemic-hyperinsulinemic clamp and indirect calorimetry. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3104
Platform:
GPL570
29 Samples
Download data: CEL
Series
Accession:
GSE6798
ID:
200006798
7.
Full record GDS3104

Insulin-resistant polycystic ovary syndrome: muscle

Analysis of vastus lateralis muscles from women with insulin-resistant polycystic ovary syndrome (PCOS). Insulin resistance in skeletal muscles is a risk factor for the development of type 2 diabetes in women with PCOS. Results provide insight into the pathogenesis of insulin resistance in PCOS.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL570
Series:
GSE6798
29 Samples
Download data: CEL
DataSet
Accession:
GDS3104
ID:
3104
8.

Type 2 diabetes and insulin resistance

(Submitter supplied) Global transcript profiling to identify differentially expressed skeletal muscle genes in insulin resistance, a major risk factor for Type II (non-insulin-dependent) diabetes mellitus. Compared gene expression profiles of skeletal muscle tissues from 18 insulin-sensitive versus 17 insulin-resistant equally obese, non-diabetic Pima Indians. Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Datasets:
GDS157 GDS158 GDS160 GDS161 GDS162
5 related Platforms
50 Samples
Download data
Series
Accession:
GSE121
ID:
200000121
9.

Insulin resistant muscle sample pool 5

(Submitter supplied) Muscle sample pool #5 from 2 insulin resistant subjects. Keywords: parallel sample
Organism:
Homo sapiens
Type:
Expression profiling by array
5 related Platforms
5 Samples
Download data
Series
Accession:
GSE73
ID:
200000073
10.

Insulin resistant muscle sample pool 4

(Submitter supplied) Muscle sample pool #4 from 3 insulin resistant subjects. Keywords: parallel sample
Organism:
Homo sapiens
Type:
Expression profiling by array
5 related Platforms
5 Samples
Download data
Series
Accession:
GSE72
ID:
200000072
11.

Insulin resistant muscle sample pool 3

(Submitter supplied) Muscle sample pool #3 from 4 insulin resistant subjects. Keywords: parallel sample
Organism:
Homo sapiens
Type:
Expression profiling by array
5 related Platforms
5 Samples
Download data
Series
Accession:
GSE71
ID:
200000071
12.

Insulin resistant muscle sample pool 2

(Submitter supplied) Muscle sample pool #2 from 4 insulin resistant subjects. Keywords: parallel sample
Organism:
Homo sapiens
Type:
Expression profiling by array
5 related Platforms
5 Samples
Download data
Series
Accession:
GSE70
ID:
200000070
13.

Insulin resistant muscle sample pool 1

(Submitter supplied) Muscle sample pool #1 from 4 insulin resistant subjects. Keywords: parallel sample
Organism:
Homo sapiens
Type:
Expression profiling by array
5 related Platforms
5 Samples
Download data
Series
Accession:
GSE69
ID:
200000069
14.

Insulin sensitive muscle sample pool 5

(Submitter supplied) Muscle sample pool #5 from 4 insulin sensitive subjects. Keywords: parallel sample
Organism:
Homo sapiens
Type:
Expression profiling by array
5 related Platforms
5 Samples
Download data
Series
Accession:
GSE68
ID:
200000068
15.

Insulin sensitive muscle sample pool 4

(Submitter supplied) Muscle sample pool #4 from 3 insulin sensitive subjects. Keywords: parallel sample
Organism:
Homo sapiens
Type:
Expression profiling by array
5 related Platforms
5 Samples
Download data
Series
Accession:
GSE67
ID:
200000067
16.

Insulin sensitive muscle sample pool 3

(Submitter supplied) Muscle sample pool #3 from 3 insulin sensitive subjects. Keywords: parallel sample
Organism:
Homo sapiens
Type:
Expression profiling by array
5 related Platforms
5 Samples
Download data
Series
Accession:
GSE66
ID:
200000066
17.

Insulin sensitive muscle sample pool 2

(Submitter supplied) Muscle sample pool #2 from 4 insulin sensitive subjects. Keywords: parallel sample
Organism:
Homo sapiens
Type:
Expression profiling by array
5 related Platforms
5 Samples
Download data
Series
Accession:
GSE65
ID:
200000065
18.

Insulin sensitive muscle sample pool 1

(Submitter supplied) Muscle sample pool #1 from 4 insulin sensitive subjects. Keywords: parallel sample
Organism:
Homo sapiens
Type:
Expression profiling by array
5 related Platforms
5 Samples
Download data
Series
Accession:
GSE64
ID:
200000064
19.
Full record GDS162

Type 2 diabetes and insulin resistance (Hu35k-D)

Analysis of gene expression in pooled vastus lateralis muscle samples from insulin-sensitive and insulin-resistant equally obese, non-diabetic Pima Indians. A search for susceptibility genes for type 2 diabetes.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 metabolism sets
Platform:
GPL101
Series:
GSE121
10 Samples
Download data
DataSet
Accession:
GDS162
ID:
162
20.
Full record GDS161

Type 2 diabetes and insulin resistance (Hu35k-C)

Analysis of gene expression in pooled vastus lateralis muscle samples from insulin-sensitive and insulin-resistant equally obese, non-diabetic Pima Indians. A search for susceptibility genes for type 2 diabetes.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 metabolism sets
Platform:
GPL100
Series:
GSE121
10 Samples
Download data
DataSet
Accession:
GDS161
ID:
161
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