GEO DataSets

(Submitter supplied) Comparison of normal adult rat extraocular muscle, cardiac muscle, leg (gastrocnemius-soleus) muscle and smooth muscle (stomach wall). Affymetrix microarray chip RG-U34A was used. MAS version 5 was used to analyze the muscle group differences. Data form part of publication: FASEB Journal 17: 1370-1372, 2003 (full length article available at http://www.fasebj.org/cgi/doi/10.1096/fj.02-1108fje). Keywords: other

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS276

Platform:

GPL85

14 Samples

Download data: CEL

Examination of control adult rat extraocular muscle, cardiac muscle, leg gastroc-soleus muscle and smooth muscle from stomach wall.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 4 tissue sets

Platform:

GPL85

Series:

GSE142

14 Samples

Download data: CEL

(Submitter supplied) Conserved and muscle group-specific gene expression patterns shape postnatal development of the novel extraocular muscle phenotype. Comparison of postnatal development of extraocular and hindlimb muscle between birth and P45. Keywords: parallel sample

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS621

Platform:

GPL85

36 Samples

Download data: CEL

Analysis of hindlimb and extraocular muscle (EOM) between birth and postnatal day 45. Dissecting allotype-specific regulatory mechanisms may help explain differential muscle group sensitivity to a variety of metabolic and neuromuscular diseases.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 6 age, 2 tissue sets

Platform:

GPL85

Series:

GSE903

36 Samples

Download data: CEL

(Submitter supplied) Skeletal muscles are a diverse family of highly specialized tissues that perform a wide array of physiological activities and maintain whole-body glucose metabolism and energy homeostasis. Functional diversity is a distinctive feature of muscle tissues, which demonstrate remarkable variability in their speed of contraction, metabolic profile, resistance to fatigue, and regenerative capacity. Unsurprisingly, many disorders of skeletal muscle afflict a remarkably specific subset of tissues, including muscular dystrophies, cancer cachexia, aging sarcopenia, and amyotrophic lateral sclerosis. more...

Organism:

Mus musculus; Rattus norvegicus

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL14844 GPL13112

126 Samples

Download data: BED, TXT

(Submitter supplied) The extraocular muscles (EOM) are anatomically and physiologically distinct from other skeletal muscles. EOM are preferentially affected in mitochondrial myopathies, but spared in Duchenne's muscular dystrophy. The anatomical and pathophysiological properties of EOM have been attributed to their unique molecular makeup: an allotype. We used expression profiling to define molecular features of the EOM allotype. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS254

Platform:

GPL85

16 Samples

Download data: CEL

Molecular definition of extraocular muscles (EOM). EOM are anatomically and physiologically distinct from other skeletal muscles.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 tissue sets

Platform:

GPL85

Series:

GSE471

16 Samples

Download data: CEL

(Submitter supplied) Although studies have established that exogenous growth hormone (GH) treatment stimulates growth in fish, its effects on target tissue gene expression are not well characterized. We assessed the effects Posilac® (Monsanto Co., St. Louis, MO), a recombinant bovine somatotropin, on tissue transcript levels. Transcript abundance was measure in liver and muscle using the GRASP 16 K cDNA microarray. A selection of the genes identified as altered with the microarray, and also transcripts for insulin-like growth factors, growth hormone receptors (GHR) and myostatins were measured by realtime PCR in the liver, muscle, brain, kidney, intestine, stomach, gill and heart. more...

Organism:

Oncorhynchus mykiss; Salmo salar

Type:

Expression profiling by array

Platform:

GPL3976

16 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Expression profiling by array

Datasets:

GDS1765 GDS1766

Platforms:

GPL340 GPL339

60 Samples

Download data: CEL

(Submitter supplied) Standard Affymetrix Protocol Keywords = microarray Keywords = muscle Keywords: time-course

Organism:

Mus musculus

Type:

Expression profiling by array

Platforms:

GPL339 GPL340

30 Samples

Download data: CEL

(Submitter supplied) Standard Affymetrix Protocol Keywords: time-course

Organism:

Mus musculus

Type:

Expression profiling by array

Platforms:

GPL339 GPL340

30 Samples

Download data: CEL

Analysis of cell lines derived from extraocular (EOM) and gastrocnemius skeletal muscle allotypes at various time points up to 48 hours following induction of myogenesis. Results provide insight into the early developmental mechanisms underlying the formation of skeletal muscle classes.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 cell type, 5 time sets

Platform:

GPL340

Series:

GSE4463

30 Samples

Download data: CEL

Analysis of cell lines derived from extraocular (EOM) and gastrocnemius skeletal muscle allotypes at various time points up to 48 hours following induction of myogenesis. Results provide insight into the early developmental mechanisms underlying the formation of skeletal muscle classes.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 cell type, 5 time sets

Platform:

GPL339

Series:

GSE4463

30 Samples

Download data: CEL

(Submitter supplied) Duchenne muscular dystrophy (DMD) is an X-linked genetic disease that affects 1 in 5,000 males. Skeletal muscle wasting occurs early in childhood, while cardiac involvement does not typically surface until a decade later. There is currently no method for predicting which patients will develop cardiomyopathy. The molecular reasons for the differences in timing and progression of cardiac dysfunction compared to skeletal dysfunction are unknown. more...

Organism:

Canis lupus familiaris

Type:

Expression profiling by array

Platform:

GPL17403

30 Samples

Download data: CEL

(Submitter supplied) Evaluation of extraocular muscle (EOM) critical period by expression profiling in dark reared rat. Data form part of publication: Investigative Ophthalmology and Visual Sciences 44: 3842-3855, 2003. Keywords: other

Organism:

Rattus norvegicus

Type:

Expression profiling by SAGE

Platform:

GPL23

2 Samples

Download data

(Submitter supplied) Extraocular Muscle is Defined by a Fundamentally Distinct Gene Expression Profile. Adult mouse extraocular, masticatory, and hindlimb (gastrocnemius/soleus) muscles of adult mice were compared using Affymetrix microarrays. Data form part of publication: Proceedings of the National Academy of Sciences USA 98:12062-12067, 2001. Keywords: parallel sample

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS702

Platform:

GPL32

14 Samples

Download data: CEL

Comparison of extraocular (EOM), masticatory (masseter), and hindlimb (gastrocnemius/soleus) muscle in 8 week old mice. EOM defined by distinct gene expression profile.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 3 tissue sets

Platform:

GPL32

Series:

GSE1062

14 Samples

Download data: CEL

(Submitter supplied) To identify biological processes as well as molecular markers for drip loss, the transcriptomes of logissimus dorsi from 6 sib pair of F2 animals Keywords: T-test paired and SAM

Organism:

Sus scrofa

Type:

Expression profiling by array

Platform:

GPL3533

12 Samples

Download data: CEL

(Submitter supplied) Rhesus monkey extraocular muscle. Data set includes: (a) whole medial and lateral rectus muscle and (b) global and orbital muscle layers separately microdissected using a Leica LSM. All samples were expression profiled here using the Affymetrix human U133 A&B arrays. Data form part of publication: Investigative Ophthalmology and Visual Science 45, 2004. Keywords = skeletal muscle Keywords = microarray Keywords = orbital layer Keywords = global layer Keywords: ordered

Organism:

Macaca mulatta; Homo sapiens

Type:

Expression profiling by array

Datasets:

GDS556 GDS557

Platforms:

GPL96 GPL97

16 Samples

Download data: CEL

Analysis of adult monkey whole medial and lateral rectus extraocular muscle (EOM), and microdissected medial rectus global and orbital EOM layers.

Organism:

Macaca mulatta; Homo sapiens

Type:

Expression profiling by array, count, 4 tissue sets

Platform:

GPL97

Series:

GSE907

8 Samples

Download data: CEL