Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO DataSets

Items: 20

1.

Mus musculus cornea experiment

(Submitter supplied) PURPOSE: To provide a detailed gene expression profile of the normal postnatal mouse cornea. METHODS: Serial analysis of gene expression (SAGE) was performed on postnatal day (PN)9 and adult mouse (6 week) total corneas. The expression of selected genes was analyzed by in situ hybridization. RESULTS: A total of 64,272 PN9 and 62,206 adult tags were sequenced. Mouse corneal transcriptomes are composed of at least 19,544 and 18,509 unique mRNAs, respectively. more...
Organism:
Mus musculus
Type:
Expression profiling by SAGE
Platform:
GPL11
2 Samples
Download data
Series
Accession:
GSE887
ID:
200000887
2.

Limbal and Central Corneal Epithelia

(Submitter supplied) Limbal and central regoins of the rat cornea epithelium were used to constract 2 SAGE libraries, in order to identify candidate genes to distinguish stem cell from differentiated central cornea epithelium cells. Keywords: gene expression SAGE-based, count
Organism:
Rattus norvegicus
Type:
Expression profiling by SAGE
Platform:
GPL23
2 Samples
Download data
Series
Accession:
GSE4121
ID:
200004121
3.

Serial analysis of gene expression in the corneal endothelium of Fuchs' dystrophy

(Submitter supplied) PURPOSE: To compare the gene expression profiles of normal human corneal endothelium with Fuchs' corneal endothelium, by using serial analysis of gene expression (SAGE). METHODS: Three pairs of normal human corneas were obtained from eye banks. Thirteen bisected Fuchs' corneal buttons were processed at the time of corneal transplantation. The endothelia of normal and Fuchs'-affected corneas were stripped, and total RNA was isolated. more...
Organism:
Homo sapiens
Type:
Expression profiling by SAGE
Platform:
GPL4
2 Samples
Download data
Series
Accession:
GSE505
ID:
200000505
4.

Extraocular muscle, expression changes in critical period (Porter lab)

(Submitter supplied) Evaluation of extraocular muscle (EOM) critical period by expression profiling in dark reared rat. Data form part of publication: Investigative Ophthalmology and Visual Sciences 44: 3842-3855, 2003. Keywords: other
Organism:
Rattus norvegicus
Type:
Expression profiling by SAGE
Platform:
GPL23
2 Samples
Download data
Series
Accession:
GSE497
ID:
200000497
5.

Gene Expression Profiling In Murine Corneal Neovascularization Models

(Submitter supplied) In order to find out the vital genes during the corneal neovascularization (CNV), we set up two CNV models, one being induced by suture placement and the other by alkali burn to the corneal center. Young adult Balb/c and C57BL/6 were used. The corneas were checked daily for CNV development and some of the corneas were removed at two pre-determined time points for RNA extraction. Preliminary experiment indicated slightly different dynamics in suture- or chemical burn-induced CNV. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10745
12 Samples
Download data: LSR
Series
Accession:
GSE23347
ID:
200023347
6.

Mouse conjunctival forniceal gene expression during postnatal development and its regulation by Kruppel-like factor 4

(Submitter supplied) Purpose: To identify the changes in postnatal mouse conjunctival forniceal gene expression and their regulation by Klf4 around eye opening stage when the goblet cells first appear. Methods: Laser-capture-microdissection was used to collect conjunctival forniceal epithelial cells from postnatal-day (PN) 9, PN14 and PN20 wild-type (WT), and PN14 Klf4-conditional null (Klf4CN) mice, where goblet cells are absent, developing, present, and missing, respectively. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
12 Samples
Download data: CEL, TXT
Series
Accession:
GSE26076
ID:
200026076
7.

Genome-Wide Binding of Ehf in mouse corneal epithelium

(Submitter supplied) The cornea, composed of epithelium, stroma and endothelium, protects the anterior compartment of the eye from damage and allows transmission of light into the eye. While well described morphologically, no studies have investigated the global gene expression changes in the cornea throughout the mouse’s life. We characterized the global gene expression profile of mouse cornea from early development through aging, and compared to gene expression in other epithelial tissue, to identify cornea enriched genes, pathways, and transcriptional regulators. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL13112
2 Samples
Download data: BED
Series
Accession:
GSE44741
ID:
200044741
8.

Expression profiling across mouse epithelial tissues

(Submitter supplied) To characterize genes, pathways, and transcriptional regulators enriched in the mouse cornea, we compared the expression profiles of whole mouse cornea, bladder, esophagus, lung, proximal small intestine, skin, stomach, and trachea.
Organism:
Mus musculus
Type:
Expression profiling by array
Platforms:
GPL1261 GPL6246
53 Samples
Download data: CEL
Series
Accession:
GSE43381
ID:
200043381
9.

A transcriptome profile of cornea over the lifetime of the mouse

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL6244 GPL6246
40 Samples
Download data: CEL
Series
Accession:
GSE43158
ID:
200043158
10.

Expression data from siRNA knockdown of Ehf in primary human corneal epithelial cells

(Submitter supplied) Ehf is a transcriptional regulator that is highly expressed and enriched in corneal epithelium. To gain insights into the role of Ehf in the corneal epithelium, we performed siRNA knockdown of Ehf in primary human corneal epithelial cells.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6244
6 Samples
Download data: CEL
Series
Accession:
GSE43157
ID:
200043157
11.

Expression profiling of wildtype mouse cornea in development, adult, and aging

(Submitter supplied) While the mouse cornea has been well characterized morphologically, the transcriptional changes have not been described in detail. To characterize the genes, pathways, and transcriptional regulators involved in mouse cornea development and aging, we isolated whole cornea from wildtype CB6 mice at several developmental timepoints and every 6 months in the adult. Corneal epithelium and stroma were isolated at one timepoint to provide insights into the genes that are unique to each tissue.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6246
34 Samples
Download data: CEL
Series
Accession:
GSE43155
ID:
200043155
12.

Differential gene expression patterns of the developing and adult mouse cornea compared to the lens and tendon

(Submitter supplied) The cornea continues to mature after birth to develop a fully functional, refractive and protective barrier tissue. Here we investigated the complex biological events underlying this process by profiling global genome-wide gene expression patterns of the immature postnatal day 10 and seven week-old adult mouse cornea. The lens and tendon were included in the study to increase the specificity of genes identified as up regulated in the corneal samples. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL81
9 Samples
Download data: CEL, CHP
Series
Accession:
GSE11900
ID:
200011900
13.

Comparative molecular analysis of developing mouse forelimbs and hindlimbs

(Submitter supplied) The analysis of differentially expressed genes is a powerful approach to elucidate the genetic mechanisms underlying the morphological and evolutionary diversity among serially homologous structures, both within the same organism (e.g., hand vs. foot) and between different species (e.g., hand vs. wing). In the developing embryo, limb-specific expression of Pitx1, Tbx4, and Tbx5 regulates the determination of limb identity. more...
Organism:
Mus musculus
Type:
Expression profiling by SAGE
Platform:
GPL11
2 Samples
Download data
Series
Accession:
GSE504
ID:
200000504
14.

RNA seq analysis of the mouse pNC and Cornea transcriptome

(Submitter supplied) Purpose: The goal of this study is to provide a detailed transcriptome expression profile of the mouse cornea and evaluate changes in gene expression during mouse corneal development. Methods: RNA-sequencing is used to profile the mouse transcriptome in the pNC isolated at E10.5 and corneas isolated at E14.5 and E16.5. Samples generated in triplicate for sequencing by Illumina Hiseq 4000. Clean reads are mapped to reference gene and GRCm38 by Bowtie2 and HISAT. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21103
9 Samples
Download data: TXT
Series
Accession:
GSE121044
ID:
200121044
15.

Gene Expression in Human Conjunctiva and Cornea

(Submitter supplied) PURPOSE. To determine global mRNA expression levels in the corneal and conjunctival epithelia and identify transcripts that exhibit preferential tissue expression. METHODS. cDNA samples derived from human conjunctival and corneal epithelia were hybridized in three independent experiments to a commercial oligonucleotide array representing > 22,000 transcripts. The resulting signal intensities and transcript present/absent calls by the primary microarray analyzing software were used in conjunction with a statistical method to identify transcripts that are preferentially or exclusively (transcripts absent in all three replicates in the other tissue) and significantly (expression >1% of the ß-actin level) expressed in one of the two tissues. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS2682
Platform:
GPL96
6 Samples
Download data
Series
Accession:
GSE5543
ID:
200005543
16.
Full record GDS2682

Conjunctiva and cornea comparison

Analysis of conjunctival (Cnj) and corneal (Co) epithelia, the main cellular components of the ocular surface. Cnj and Co epithelia are embryologically related but phenotypically and functionally disparate. Results provide insight into the molecular basis of these differences.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 tissue sets
Platform:
GPL96
Series:
GSE5543
6 Samples
Download data
17.

Profiling of spatio-temporally regulated transcripts during cerebral corticogenesis in the mouse

(Submitter supplied) The cerebral cortex plays an important role in cognitive function and specialized perception in mammals and its development requires highly specific spatio-temporal control of gene expression. The study identified stage- and region-specific markers throughout cerebral corticogenesis at various important stages of cerebral cortex development; embryonic day (E) 15.5, E17.5, postnatal day (P) 1.5 and 4-6 months old.
Organism:
Mus musculus
Type:
Expression profiling by SAGE
Platforms:
GPL1349 GPL11
12 Samples
Download data
Series
Accession:
GSE15031
ID:
200015031
18.

Gene expression profiling of mouse sclera during post-natal development

(Submitter supplied) Although there have been studies conducted on cornea and retina growth and development, postnatal gene expression studies on sclera growth during postnatal growth has not been well characterised. Given that the mouse genome has 85% homology to the human genome and has been completely sequenced, mouse model for the study of ocular growth has advantages over other animal models. Thus, we aimed to study the biology and genetics behind sclera growth during post-natal development in Balb/cJ mice as a means to understand genetic changes that cause scleral growth and development during post-natal eye development The purpose of this study was to identify the genes underlying the development of mouse sclera post-natal growth of the posterior chamber of the eye using microarray
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6246
30 Samples
Download data: CEL
Series
Accession:
GSE28056
ID:
200028056
19.

Dynamic changes in the functions of Klf5 in maturing mouse corneas revealed by the changes in its target genes at postnatal days 11 and 56

(Submitter supplied) Purpose: Klf5 plays a critical role in the mouse ocular surface (Kenchegowda et al., 2011. Dev Biol. 356:5-18). Here, we compare wild-type (WT) and Klf5-conditional null (Klf5CN) corneal gene expression at postnatal day-11 (PN11) and PN56 to identify the Klf5-target genes. Methods: Gene expression was compared using Affymetrix microarrays with QPCR validation. Transient transfection assays examined the effect of Klf5 on selected target gene promoter activities. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
14 Samples
Download data: CEL, TXT
Series
Accession:
GSE36229
ID:
200036229
20.

Differential gene expression of Appresorium vs Vegetative mycelium of Magnaporthe using oligoarray

(Submitter supplied) Rice blast, caused by the fungal pathogen Magnaporthe grisea, is a devastating disease causing tremendous yield loss in rice production. The public availability of the complete genome sequence of M. grisea provides ample opportunities to understand the molecular mechanism of its pathogenesis on rice plants at the transcriptome level. To identify all the expressed genes encoded in the fungal genome, we have analyzed the mycelium and appressorium transcriptomes using MPSS, RL-SAGE and oligoarray methods. more...
Organism:
Pyricularia grisea
Type:
Expression profiling by array; Expression profiling by SAGE
Platforms:
GPL4080 GPL4085
2 Samples
Download data: TXT
Series
Accession:
GSE5518
ID:
200005518
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=|query=1|qty=5|blobid=MCID_610beccaa153286da07456a8|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center