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Links from GEO DataSets

Items: 20

1.

The pattern of gene expression in human CD34(+) stem/progenitor cells

(Submitter supplied) We have analyzed the pattern of gene expression in human primary CD34(+) stem/progenitor cells. We identified 42,399 unique serial analysis of gene expression (SAGE) tags among 106,021 SAGE tags collected from 2.5 x 10(6) CD34(+) cells purified from bone marrow. Of these unique SAGE tags, 21,546 matched known expressed sequences, including 3,687 known genes, and 20,854 were novel without a match. The SAGE tags that matched known sequences tended to be at higher levels, whereas the novel SAGE tags tended to be at lower levels. more...
Organism:
Homo sapiens
Type:
Expression profiling by SAGE
Platform:
GPL4
1 Sample
Download data
Series
Accession:
GSE2346
ID:
200002346
2.

The pattern of gene expression in human CD15+ myeloid progenitor cells

(Submitter supplied) We performed a genome-wide analysis of gene expression in primary human CD151 myeloid progenitor cells. By using the serial analysis of gene expression (SAGE) technique, we obtained quantitative information for the expression of 37,519 unique SAGE-tag sequences. Of these unique tags, (i) 25% were detected at high and intermediate levels, whereas 75% were present as single copies, (ii) 53% of the tags matched known expressed sequences, 34% of which were matched to more than one known expressed sequence, and (iii) 47% of the tags had no matches and represent potentially novel genes. more...
Organism:
Homo sapiens
Type:
Expression profiling by SAGE
Platform:
GPL4
1 Sample
Download data
Series
Accession:
GSE13007
ID:
200013007
3.

Extraocular muscle, expression changes in critical period (Porter lab)

(Submitter supplied) Evaluation of extraocular muscle (EOM) critical period by expression profiling in dark reared rat. Data form part of publication: Investigative Ophthalmology and Visual Sciences 44: 3842-3855, 2003. Keywords: other
Organism:
Rattus norvegicus
Type:
Expression profiling by SAGE
Platform:
GPL23
2 Samples
Download data
Series
Accession:
GSE497
ID:
200000497
4.

A SAGE approach to discovery of apolipoprotein E4 allele-specific genes involved in increased risk in Alzheimer disease

(Submitter supplied) APOE4 allele is a major risk factor for late-onset Alzheimer disease (AD). The mechanism of action of APOE in AD remains unclear. To study the effects of APOE alleles on gene expression in AD, we have analyzed the gene transcription patterns of human hippocampus from APOE3/3, APOE3/4, APOE4/4 AD patients and normal control using Serial Analysis of Gene Expression (SAGE). Using SAGE, we found gene expression patterns in hippocampus of APOE3/4 and APOE4/4 AD patients differ substantially from those of APOE3/3 AD patients. more...
Organism:
Homo sapiens
Type:
Expression profiling by SAGE
Platforms:
GPL4 GPL1485
6 Samples
Download data
Series
Accession:
GSE6677
ID:
200006677
5.

Lin-, CD38-, CD34+ Hematopoietic Stem Cells.

(Submitter supplied) Lin-, CD38-, CD34+ hematopoietic stem cells. Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL96 GPL97
6 Samples
Download data: CEL, EXP
Series
Accession:
GSE3788
ID:
200003788
6.

Comparative molecular analysis of developing mouse forelimbs and hindlimbs

(Submitter supplied) The analysis of differentially expressed genes is a powerful approach to elucidate the genetic mechanisms underlying the morphological and evolutionary diversity among serially homologous structures, both within the same organism (e.g., hand vs. foot) and between different species (e.g., hand vs. wing). In the developing embryo, limb-specific expression of Pitx1, Tbx4, and Tbx5 regulates the determination of limb identity. more...
Organism:
Mus musculus
Type:
Expression profiling by SAGE
Platform:
GPL11
2 Samples
Download data
Series
Accession:
GSE504
ID:
200000504
7.

Serial analysis of gene expression in the corneal endothelium of Fuchs' dystrophy

(Submitter supplied) PURPOSE: To compare the gene expression profiles of normal human corneal endothelium with Fuchs' corneal endothelium, by using serial analysis of gene expression (SAGE). METHODS: Three pairs of normal human corneas were obtained from eye banks. Thirteen bisected Fuchs' corneal buttons were processed at the time of corneal transplantation. The endothelia of normal and Fuchs'-affected corneas were stripped, and total RNA was isolated. more...
Organism:
Homo sapiens
Type:
Expression profiling by SAGE
Platform:
GPL4
2 Samples
Download data
Series
Accession:
GSE505
ID:
200000505
8.

Molecular phenotype of G-CSF- or pegylated G-CSF-mobilized CD34+ cells

(Submitter supplied) Peripheral blood stem and progenitor cells (PBSC) are widely used for autologous and allogeneic hematopoietic stem cell transplantation. PBSC can be mobilized into the peripheral blood using cytokines, cytotoxic chemotherapy or a combination of both. Granulocyte colony stimulating factor (G-CSF) has become the most commonly administered cytokine for PBSC mobilization because of its high potency and lack of serious toxicity. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS2321
Platform:
GPL201
16 Samples
Download data
Series
Accession:
GSE4688
ID:
200004688
9.
Full record GDS2321

Polyethylene glycol-conjugated G-CSF mobilized CD34+ cells

Analysis of granulocyte colony stimulating factor (G-CSF) or polyethylene glycol-conjugated (pegylated) G-CSF mobilized CD34+ hematopoietic stem and progenitor cells from multiple myeloma patients undergoing chemotherapy. Pegylated G-CSF has a longer half-life than unconjugated G-CSF.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent sets
Platform:
GPL201
Series:
GSE4688
16 Samples
Download data
DataSet
Accession:
GDS2321
ID:
2321
10.

Mus musculus hematopoietic stem cell

(Submitter supplied) A transcriptome study in mouse hematopoietic stem cells was performed using a sensitive SAGE method, in an attempt to detect medium and low abundant transcripts expressed in these cells. Among a total of 31,380 unique transcript, 17,326 (55%) known genes were detected, 14,054 (45%) low-copy transcripts that have no matches to currently known genes. 3,899 (23%) were alternatively spliced transcripts of the known genes and 3,754 (22%) represent anti-sense transcripts from known genes.
Organism:
Mus musculus
Type:
Expression profiling by SAGE
Platform:
GPL11
1 Sample
Download data
Series
Accession:
GSE16139
ID:
200016139
11.

SAGE analysis of A. thaliana leaf tissue

(Submitter supplied) Arabidopsis thaliana (Col-4) aerial tissue collected from 14-day old plants. Grown under sterile conditions at 22 degrees Celsius and 125 uE light on 0.5xMS media.
Organism:
Arabidopsis thaliana
Type:
Expression profiling by SAGE
Platform:
GPL25
1 Sample
Download data
Series
Accession:
GSE25993
ID:
200025993
12.

SAGE libraries from mouse

(Submitter supplied) SAGE libraries from mouse
Organism:
Mus musculus
Type:
Expression profiling by SAGE
Platform:
GPL11
5 Samples
Download data
Series
Accession:
GSE25749
ID:
200025749
13.

Bombyx mori Posterior and Median Silk Gland SAGE transcriptome

(Submitter supplied) To identify functions that distinguish the posterior and median cells producing fibroin and sericin in the silk gland of Bombyx mori, serial analysis of gene expression (SAGE) profiles from both silk gland regions were analyzed and compared. The construction of a B. mori reference tag collection extracted from a set of 38000 Bombyx EST sequenced from the 3’ side, helped annotating the SAGE libraries. more...
Organism:
Bombyx mori
Type:
Expression profiling by SAGE
Platform:
GPL2095
2 Samples
Download data
Series
Accession:
GSE23098
ID:
200023098
14.

LongSAGE transcriptome profiling in the widespread marine coccolithophore Emiliania huxleyi

(Submitter supplied) The abundant and widespread coccolithophore Emiliania huxleyi plays an important role in mediating CO2 exchange between the ocean and the atmosphere through its impact on marine photosynthesis and calcification. Here, we use long serial analysis of gene expression (SAGE) to identify E. huxleyi genes responsive to nitrogen (N) or phosphorus (P) starvation. Long SAGE is an elegant approach for examining quantitative and comprehensive gene expression patterns without a priori knowledge of gene sequences via the detection of 21-bp nucleotide sequence tags. more...
Organism:
Emiliania huxleyi CCMP1516
Type:
Expression profiling by SAGE
Platform:
GPL5469
3 Samples
Download data
Series
Accession:
GSE8376
ID:
200008376
15.

SAGE analysis of normal human thyroid tissue

(Submitter supplied) This library was generated from normal human thyroid tissue collected at routine autopsy. Standard SAGE protocol was used (Velculescu et al. Science 1995). Data from this library was published in: 'Pauws E, Moreno JC, Tijssen M, Baas F, de Vijlder JJ, Ris-Stalpers C. J Clin Endocrinol Metab. 2000 May;85(5):1923-7' Data was generated and analyzed at the laboratory of Pediatric Endocrinology, Academic Medial Center, Amsterdam, The Netherlands.
Organism:
Homo sapiens
Type:
Expression profiling by SAGE
Platform:
GPL4
1 Sample
Download data
Series
Accession:
GSE25754
ID:
200025754
16.

SAGE profile of rat hippocampus mRNA from Wistar rats

(Submitter supplied) SAGE profile of rat hippocampus mRNA from Wistar rats
Organism:
Rattus norvegicus
Type:
Expression profiling by SAGE
Platform:
GPL23
1 Sample
Download data
Series
Accession:
GSE25750
ID:
200025750
17.

Gene Expression Profiles with Common Translocations in Acute Myeloid Leukemia (AML) using SAGE

(Submitter supplied) SAGE was used to profile gene expression in leukemic myeloid progenitor cells of AML patients with t(8;21), t(15;17), t(9;11) and inv(16). Keywords: SAGE analysis of gene expression in leukemic myeloid progenitor cells isolated from bone marrow
Organism:
Homo sapiens
Type:
Expression profiling by SAGE
Platform:
GPL4
22 Samples
Download data
Series
Accession:
GSE3255
ID:
200003255
18.

Bovine Glomerular and Aortic Endothelial Cells

(Submitter supplied) SAGE libraries were prepared from mRNA of cultured bovine glomerular and aortic endothelial cells. Cells both cell lines were positive for acetylated LDL uptake and vWF expression, and were proven to be free of non-endothelial cells. Cultures were studied at passage 9-10. The cells were confluent, cultured in parallel, under identical conditions. Cells were plated on gelatin coated cell culture plastic in RPMI 1640 medium containing 10% FBS and streptomycin/penicillin. more...
Organism:
Bos taurus
Type:
Expression profiling by SAGE
Platform:
GPL223
2 Samples
Download data
Series
Accession:
GSE110
ID:
200000110
19.

Detecting novel low-abundant transcripts in Drosophila

(Submitter supplied) Increasing evidence suggests that low-abundant transcripts may play fundamental roles in biological processes. In an attempt to estimate the prevalence of low-abundant transcripts in eukaryotic genomes, we performed a transcriptome analysis in Drosophila using the SAGE technique. We collected 244,313 SAGE tags from transcripts expressed in Drosophila embryonic, larval, pupae, adult, and testicular tissue. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by SAGE
Platform:
GPL1882
5 Samples
Download data
Series
Accession:
GSE2347
ID:
200002347
20.

LSAGE Library Human Renal Glomeruli

(Submitter supplied) Glomeruli were isolated from the kidney of a 72 yo male patient. The kidney was surgically removed due to renal cell carcinoma. The glomeruli were isolated from uninvolved renal parenchyma. Histology (H&E) of glomeruli and interstitium was normal. Keywords: Kidney Subcompartment
Organism:
Homo sapiens
Type:
Expression profiling by SAGE
Platform:
GPL1485
1 Sample
Download data
Series
Accession:
GSE8114
ID:
200008114
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