Similar studies for GEO DataSets (Select 200002838) - GEO DataSets

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Items: 20

Select item 2000028381.

Comparative SAGE Analysis of the Response to Hypoxia in Human Pulmonary and Aortic Endothelial Cells

(Submitter supplied) Cultures of human aortic (HAEC) and pulmonary artery endothelial cells (HPAEC) were exposured to short-term chronic hypoxia (1% O2) for either 0h, 8h or 24h Keywords: Time course, cell-type comparison

Organism:: Homo sapiens

Type:: Expression profiling by SAGE

Platform:: GPL4
6 Samples

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Series

Accession:: GSE2838

ID:: 200002838

PubMed Similar studies

Select item 2000027192.

Gene expression of human soft tissue sarcoma

(Submitter supplied) Gene expression profiles of 39 human sarcoma samples (GSM 52571-GSM52609) and 15 control samples (GSM52556-GSM52570) were assessed using Affymetrix HG U133A oligonucleotide arrays. Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS1209
Platform:: GPL96
54 Samples

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Series

Accession:: GSE2719

ID:: 200002719

Select item 12093.

Sarcoma and hypoxia

Expression profiling of soft tissue sarcoma samples. Hypoxic regions often develop in tumors as they increase in size. Results provide insight into the expression of hypoxia-related genes in sarcomas.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 disease state, 23 tissue sets

Platform:: GPL96
Series:: GSE2719
54 Samples

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DataSet

Accession:: GDS1209

ID:: 1209

Select item 2000036964.

Rat brain microvessel SAGE

(Submitter supplied) SAGE analysis of genes expressed in rat brain microvessels. Keywords: Novel gene identification

Organism:: Rattus norvegicus

Type:: Expression profiling by SAGE

Platform:: GPL23
1 Sample

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Series

Accession:: GSE3696

ID:: 200003696

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Select item 2000089145.

CHRF-288-11 and primary human megakaryocytic cell cultures provide novel insights into lineage-specific differentiation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2926
Platform:: GPL887
77 Samples

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Series

Accession:: GSE8914

ID:: 200008914

Select item 2000038396.

Temporal expression profile of megakaryocytic differentiation primary CD34+ cell culture

(Submitter supplied) Little is known about the global transcriptional program underlying megakaryocytic (Mk) differentiation, maturation, and apoptosis. Using DNA microarrays and Q-RT-PCR, we examined the transcriptional profile of Mk differentiation human CD34-positive hematopoietic stem and progenitor cells cultured with thrombopoietin, interleukin-3, and Flt3-ligand. The goal this study was to identify genes involved in the various facets of Mk differentiation including commitment, polyploidization, proplatelet formation, and apoptosis. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL887
36 Samples

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Series

Accession:: GSE3839

ID:: 200003839

Select item 2000038387.

Temporal expression profile of CHRF-288 cell line after phorbol ester stimulation

(Submitter supplied) Little is known about the global transcriptional program underlying megakaryocytic (Mk) differentiation, maturation, and apoptosis. Using DNA microarrays and Q-RT-PCR, we examined the transcriptional profile of phorbol-ester-induced Mk differentiation of the megakaryoblastic CHRF-288-11 (CHRF) cell line – a model system for investigating megakaryopoiesis. The goals of this study were to (1) verify the megakaryocytic nature of the CHRF cell line at the transcriptional level, and (2) extract novel insights into the key facets of Mk maturation including polyploidization, proplatelet formation, and apoptosis. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL887
41 Samples

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Series

Accession:: GSE3838

ID:: 200003838

Select item 29268.

Megakaryocytic differentiation: time course

Temporal analysis of phorbol ester-treated CHRF-288-11 megakaryoblastic cells induced to undergo megakaryocytic (Mk) differentiation and primary Mk (PriMk) cells derived from cytokine-treated CD34+ peripheral blood cells. Results provide insight into molecular mechanisms underlying megakaryopoiesis.

Organism:: Homo sapiens

Type:: Expression profiling by array, log e ratio, 4 agent, 2 cell line, 13 time sets

Platform:: GPL887
Series:: GSE8914
77 Samples

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DataSet

Accession:: GDS2926

ID:: 2926

Select item 2000031189.

Comparison of expression profile between human Müller cells, HMCL-I and HMCL-II

(Submitter supplied) Müller cells are the principal glial cells in the retina. Alterations in Müller cell behaviour are observed in retinal tissue from patients with proliferative diabetic retinopathy. The purpose of this study was to compare gene and protein expression profile of normal human Müller cells (NHMC) with two spontaneously human Müller cell lines generated from type 1 (HMCL-I) and type 2 (HMCL-II) diabetic donors using Serial Analysis Gene Expression (SAGE). more...

Organism:: Homo sapiens

Type:: Expression profiling by SAGE

Platform:: GPL2750
3 Samples

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Series

Accession:: GSE3118

ID:: 200003118

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Select item 20000448310.

Astrocyte and Hela cell response to hypoxia

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS1779
Platform:: GPL570
12 Samples

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Series

Accession:: GSE4483

ID:: 200004483

Select item 20000305111.

HeLa response to hypoxia

(Submitter supplied) Oxygen is vital for the development and survival of mammals. In response to hypoxia, the brain initiates numerous adaptive responses at the organ level as well as at the molecular and cellular level, including the alteration of gene expression. Astrocytes play critical roles in the proper functioning of the brain, thus the manner in which astrocytes respond to hypoxia is likely important in determining the outcome of brain hypoxia. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
6 Samples

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Series

Accession:: GSE3051

ID:: 200003051

Select item 20000304512.

Astrocytic response to hypoxia

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
6 Samples

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Series

Accession:: GSE3045

ID:: 200003045

Select item 177913.

Hypoxia effect on astrocytes

Analysis of purified primary astrocytes exposed to hypoxia for 24 hours. Gene expression in HeLa cells also examined. Astrocytes play critical roles in the proper functioning of the brain. Results provide insight into the molecular events underlying the astrocytic responses to hypoxia.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 cell type, 2 stress sets

Platform:: GPL570
Series:: GSE4483
12 Samples

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DataSet

Accession:: GDS1779

ID:: 1779

Select item 20001254614.

Gene and exon expression of Human Umbilical Vein Endothelial Cell under Mimic Hypoxia Stress

(Submitter supplied) Human umbilical vein endothelial cells (HUVECs) were insulted with cobalt chloride to induce cell apoptosis and alternative splicing in the mimic-hypoxia environment. We use Affymetrix exon array to reveal differential expression from transcript-level and exon-level in genome-wide.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL5188 GPL5175
12 Samples

Download data: CEL

Series

Accession:: GSE12546

ID:: 200012546

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20002682015.

Expression data from GFAP-negative LC cells exposed to 24 hours of hypoxia

(Submitter supplied) Vascular hypoperfusion is a pathological phenomenon in the glaucomatous optic nerve head. We report transcriptional responses in GFAP-negative LC cells exposed to in-vitro hypoxic stress (1%O2).

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
6 Samples

Download data: CEL

Series

Accession:: GSE26820

ID:: 200026820

Select item 20000050516.

Serial analysis of gene expression in the corneal endothelium of Fuchs' dystrophy

(Submitter supplied) PURPOSE: To compare the gene expression profiles of normal human corneal endothelium with Fuchs' corneal endothelium, by using serial analysis of gene expression (SAGE). METHODS: Three pairs of normal human corneas were obtained from eye banks. Thirteen bisected Fuchs' corneal buttons were processed at the time of corneal transplantation. The endothelia of normal and Fuchs'-affected corneas were stripped, and total RNA was isolated. more...

Organism:: Homo sapiens

Type:: Expression profiling by SAGE

Platform:: GPL4
2 Samples

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Series

Accession:: GSE505

ID:: 200000505

PubMed Similar studies

Select item 20000011017.

Bovine Glomerular and Aortic Endothelial Cells

(Submitter supplied) SAGE libraries were prepared from mRNA of cultured bovine glomerular and aortic endothelial cells. Cells both cell lines were positive for acetylated LDL uptake and vWF expression, and were proven to be free of non-endothelial cells. Cultures were studied at passage 9-10. The cells were confluent, cultured in parallel, under identical conditions. Cells were plated on gelatin coated cell culture plastic in RPMI 1640 medium containing 10% FBS and streptomycin/penicillin. more...

Organism:: Bos taurus

Type:: Expression profiling by SAGE

Platform:: GPL223
2 Samples

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Series

Accession:: GSE110

ID:: 200000110

PubMed Similar studies

Select item 20000557918.

Hypoxia and lymphatic endothelial cells

(Submitter supplied) Lymphatic endothelial cells were grown under normoxia, hypoxia (1% 0xygen) and conditioned medio from NSLCN growth under normoxia or hypoxia. Gene expression was measured and comparition between samples performed Keywords: Comparative genomic hybridization

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2902
Platform:: GPL570
4 Samples

Download data: CEL, EXP

Series

Accession:: GSE5579

ID:: 200005579

Select item 290219.

Hypoxia and lymphathic endothelial cells

Analysis of lymphatic endothelial cells (LECs) subjected to hypoxia or treated with conditioned media from lung carcinoma cells grown under hypoxic conditions. LECs contribute to tumor metastasis.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 4 protocol sets

Platform:: GPL570
Series:: GSE5579
4 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS2902

ID:: 2902

Select item 20000042020.

Aortic stiffness

(Submitter supplied) BACKGROUND: Previous genomic studies with human tissues have compared differential gene expression between 2 conditions (ie, normal versus diseased) to identify altered gene expression in a binary manner; however, a potentially more informative approach is to correlate the levels of gene expression with quantitative physiological parameters. METHODS AND RESULTS: In this study, we have used this approach to examine genes whose expression correlates with arterial stiffness in human aortic specimens. more...