Similar studies for GEO DataSets (Select 200003788) - GEO DataSets

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Items: 20

Select item 2000037881.

Lin-, CD38-, CD34+ Hematopoietic Stem Cells.

(Submitter supplied) Lin-, CD38-, CD34+ hematopoietic stem cells. Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL96 GPL97
6 Samples

Download data: CEL, EXP

Series

Accession:: GSE3788

ID:: 200003788

Select item 2000046882.

Molecular phenotype of G-CSF- or pegylated G-CSF-mobilized CD34+ cells

(Submitter supplied) Peripheral blood stem and progenitor cells (PBSC) are widely used for autologous and allogeneic hematopoietic stem cell transplantation. PBSC can be mobilized into the peripheral blood using cytokines, cytotoxic chemotherapy or a combination of both. Granulocyte colony stimulating factor (G-CSF) has become the most commonly administered cytokine for PBSC mobilization because of its high potency and lack of serious toxicity. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2321
Platform:: GPL201
16 Samples

Download data

Series

Accession:: GSE4688

ID:: 200004688

Select item 23213.

Polyethylene glycol-conjugated G-CSF mobilized CD34+ cells

Analysis of granulocyte colony stimulating factor (G-CSF) or polyethylene glycol-conjugated (pegylated) G-CSF mobilized CD34+ hematopoietic stem and progenitor cells from multiple myeloma patients undergoing chemotherapy. Pegylated G-CSF has a longer half-life than unconjugated G-CSF.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 agent sets

Platform:: GPL201
Series:: GSE4688
16 Samples

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DataSet

Accession:: GDS2321

ID:: 2321

Select item 2000014934.

Hematopoietic stem cell subsets

(Submitter supplied) Hematopoietic stem cell (HSC) subsets based on the CD34 expression and/or lineage markers expression Keywords: parallel sample

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS1095
Platform:: GPL8300
6 Samples

Download data

Series

Accession:: GSE1493

ID:: 200001493

Select item 10955.

Hematopoeitic stem cells of various types

Expression profiling of Lin-CD34-, Lin-CD34+, and Lin+CD34+ peripheral blood hematopoeitic stem cells (HSCs). Results provide insight into the molecular basis of the association of CD34 expression with self-renewal and lineage commitment in HSCs.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 cell type sets

Platform:: GPL8300
Series:: GSE1493
6 Samples

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DataSet

Accession:: GDS1095

ID:: 1095

Select item 2000030036.

Gene expression profiling of CD34+ hematopoietic cells expanded in a collagen I matrix

(Submitter supplied) CD34+ hematopoietic stem/progenitor cells (HSC) reside in the bone marrow in close vicinity to the endosteal bone surface, surrounded by osteoblasts, stromal cells and various extracellular matrix molecules. We utilized a bioartificial matrix containing fibrillar collagen I, the major matrix component of bone, as scaffold for ex vivo expansion of HSCs. CD34+ HSCs were isolated from umbilical cord blood and cultivated within reconstituted collagen I fibrils in presence of FLT3-ligand, SCF and IL-3. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS1401
Platform:: GPL96
6 Samples

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Series

Accession:: GSE3003

ID:: 200003003

Select item 14017.

CD34+ hematopoietic cells expanded in artificial matrix of fibrillar collagen I

Analysis of CD34+ hematopoietic stem/progenitor cells (HSC) expanded for 7 days in an artificial matrix of fibrillar collagen I, the major matrix component of bone. Results provide insight into the limitations of ex vivo expansion to increase the number of transplantable HSCs from cord blood.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 growth protocol sets

Platform:: GPL96
Series:: GSE3003
6 Samples

Download data

DataSet

Accession:: GDS1401

ID:: 1401

Select item 2000080408.

CD34 antigen role in haematopoietic commitment

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
6 Samples

Download data: CEL

Series

Accession:: GSE8040

ID:: 200008040

Select item 2000080039.

CD34 Overexpression

(Submitter supplied) In order to investigate the role of CD34 antigen in haematopoietic commitment, we overexpressed the human CD34 cDNA in human CD34+ cells by retroviral gene transfer. Keywords: treatment comparison

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
3 Samples

Download data: CEL

Series

Accession:: GSE8003

ID:: 200008003

Select item 20000800210.

CD34 gene silencing

(Submitter supplied) In order to investigate the role of CD34 antigen in haematopoietic commitment, we silenced the CD34 gene expression in CD34+ stem/progenitor cells using a siRNA approach. Keywords: treatment comparison

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
3 Samples

Download data: CEL

Series

Accession:: GSE8002

ID:: 200008002

Select item 20000266611.

Human Hematopoietic Stem Cell (HSC) and Progenitor Cell (HPC) Expression Profilies

(Submitter supplied) The global gene expression profiles of human umbilical cord blood and adult bone marrow CD34+CD33-CD38-Rho(lo)c-kit+ cells, enriched for hematopoietic stem/progenitor cells (HSC) with CD34+CD33-CD38-Rho(hi) cells, enriched in committed hematopoietic progenitor cells (HPC), were compared to identify candidate regulators of HSC self-renewal versus differentiation fate decisions. Keywords: parallel sample

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS1230 GDS1231
Platforms:: GPL97 GPL96
36 Samples

Download data: CEL, EXP

Series

Accession:: GSE2666

ID:: 200002666

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 123112.

Hematopoietic stem cell and progenitor cell comparison (HG-U133B)

Comparison of CD34+CD33-CD38-Rho(lo)c-kit+ cells, enriched for hematopoietic stem/progenitor cells (HSC), to CD34+CD33-CD38-Rho(hi) cells, enriched for committed hematopoietic progenitor cells (HPC). Cells obtained from umbilical cord blood and bone marrow. Provides insight into control of HSC fate.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 cell type, 2 tissue sets

Platform:: GPL97
Series:: GSE2666
18 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS1231

ID:: 1231

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 123013.

Hematopoietic stem cell and progenitor cell comparison (HG-U133A)

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 cell type, 2 tissue sets

Platform:: GPL96
Series:: GSE2666
18 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS1230

ID:: 1230

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 20000341014.

IM CD34+ progenitors cells

(Submitter supplied) IM CD34+ vs BM CD34+ cells Keywords: parallel sample

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2397
Platform:: GPL96
6 Samples

Download data

Series

Accession:: GSE3410

ID:: 200003410

Select item 239715.

Idiopathic myelofibrosis: hematopoietic CD34+ stem cells

Analysis of pooled hematopoietic CD34+ stem cells from peripheral blood of patients with idiopathic myelofibrosis (IM), a rare chronic myeloproliferative disorder. Results provide insight into the molecular pathogenesis of IM.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 disease state sets

Platform:: GPL96
Series:: GSE3410
6 Samples

Download data

DataSet

Accession:: GDS2397

ID:: 2397

Select item 20010749716.

Genomic analysis for hematopoietic stem and progenitors cells (HSPC) generated in vitro according to ex vivo expansion protocols and their comparison with HSPC obtained fresh

(Submitter supplied) Expansion for hematopoietic cells from umbilical cord blood is a strategy for use this cell source in clinic transplants, however, it is important to know about the genomic changes that can occur in expanded cells. In order to detect global expression profiles changes in hematopoietic stem and progenitors cells generated in vitro, we analyzed hematopoietics populations obtained by FACS in fresh from umbilical cord blood. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL17586
19 Samples

Download data: CEL, CHP

Series

Accession:: GSE107497

ID:: 200107497

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20001924017.

Expression profile of IL-1beta stimulated and non-stimulated endothelial cells

(Submitter supplied) Complete identification of the bone marrow niche remains one of the most progressing fields. Attempts to identify soluble factors involved in stem cell renewal have been less successful. We have previously shown that endothelial cells (EC) can induce the long-term proliferation of hematopoietic progenitor cells (HPC), especially when they had been subjected to an inflammatory stimulus like interleukins (IL) 1. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
6 Samples

Download data: CEL

Series

Accession:: GSE19240

ID:: 200019240

Select item 20002089118.

SDF-1 induced transcriptional changes in human cord blood CD34+ cells

(Submitter supplied) We have employed whole genome microarray expression profiling to identify genes differentially expressed in cord blood enriched CD34+ cells(>95%) after a short-term exposure to the chemokine stromal cell-derived factor-1 (SDF-1).

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
8 Samples

Download data: CEL, CHP

Series

Accession:: GSE20891

ID:: 200020891

Select item 20001544919.

Thrombopoietin (TPO) protects against heart damage induced by doxorubicin and infarction in rat models

(Submitter supplied) In order to examine the mechanism of TPO on cardiac protection against DOX damage, we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the potential to delineate the TPO cardioprotective mechanism against DOX-induced cardiomyopathy

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL7294
8 Samples

Download data: TXT

Series

Accession:: GSE15449

ID:: 200015449

Select item 20001961020.

Gene expression profiling of myelodysplastic CD34+ hematopoietic stem cells treated in vitro with decitabine

(Submitter supplied) Epigenetic mechanisms contribute to deregulated gene expression of hematopoietic progenitors in Myelodysplastic Syndromes (MDS). Hypomethylating agents are able to improve peripheral cytopenias in MDS patients. To identify critical gene expression changes induced by hypomethylating agents, we analyzed gene expression profiling (GEP) of myelodysplastic and normal CD34+ hematopoietic stem cells treated in vitro with or without decitabine. more...