GEO DataSets

(Submitter supplied) Abstract: Analysis of the patterns of gene expression in follicular lymphomas from 24 patients suggested that two groups of tumors might be distinguished. All patients, whose biopsies were obtained before any treatment, were treated with rituximab, a monoclonal antibody directed against the B cell antigen, CD20. Gene expression patterns in the tumors that subsequently failed to respond to rituximab appeared more similar to those of normal lymphoid tissues than to gene expression patterns of tumors from rituximab responders. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL3042 GPL3113 GPL3114

48 Samples

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(Submitter supplied) 24 independent follicular lymphoma lymph node samples on LC microarrays was used to generate the gene lists in tables 2 and 3 of publication patients were divided into two groups, rituximab responders (composed of CR and PR) and non-responders (composed of NR and MR). Set of arrays organized by shared biological context, such as organism, tumors types, processes, etc. Keywords: Logical Set

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS1839

Platform:

GPL3113

24 Samples

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(Submitter supplied) 20 FL lymph node samples from 16 patients and four normal lymphoid tissues (two tonsil and two spleen) from four different patient. Data can be viewed on the supplemental website at http://genome-www.stanford.edu/rituximab/. Set of arrays organized by shared biological context, such as organism, tumors types, processes, etc. Keywords: Logical Set

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL3042 GPL3114

24 Samples

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Analysis of lymph node biopsies from 24 follicular lymphoma patients. Biopsies obtained before any systemic therapy. Results analyzed together with the subsequent response of patients to rituximab, a monoclonal antibody directed against the B cell antigen, CD20.

Organism:

Homo sapiens

Type:

Expression profiling by array, log2 ratio, 3 disease state sets

Platform:

GPL3113

Series:

GSE3647

24 Samples

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(Submitter supplied) We investigated the biological features of FL and their relationship to patients’ outcome. Gene expression analysis was carried out on diagnosis biopsies from 148 follicular lymphoma patients enrolled in the PRIMA clinical trial. We developed a gene expression-based predictor of progression-free survival (PFS) in high-tumour burden FL patients and we analysed gene-expression signatures reflecting different aspects of tumour biology for their association with outcome. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

149 Samples

Download data: CEL