Similar studies for GEO DataSets (Select 200004459) - GEO DataSets

Select item 2000044591.

Gene expression signature and the prediction of lymph node metastases

(Submitter supplied) Samples were taken from colorectal cancers in surgically resected specimens in 89 colorectal cancer patients. The expression profiles were determined using Affymetrix Human Genome U133 Plus 2.0 arrays. Comparison between the sample groups allow to identify a set of discriminating genes that can be used for molecular markers for predicting lymph node metastases. Keywords: disease state analysis

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
89 Samples

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Series

Accession:: GSE4459

ID:: 200004459

Select item 2000045262.

Gene expression signature and the prediction of recurrence in stage III colorectal cancer by DNA microarray

(Submitter supplied) Samples were taken from colorectal cancers in surgically resected specimens in 36 colorectal cancer patients. The expression profiles were determined using Affymetrix Human Genome U133 Plus 2.0 arrays. Comparison between the sample groups allow to identify a set of discriminating genes that can be used for molecular markers for predicting recurrence. Keywords: repeat

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
36 Samples

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Series

Accession:: GSE4526

ID:: 200004526

Select item 2000036293.

Molecular Marker for predicting development of cancer in ulcerative colitis

(Submitter supplied) Samples were taken from either surgically resected specimens or during surveillance colonoscopic examination. The expression profiles were determined using Affymetrix Human Genome U133 Plus 2.0 arrays. Comparison between the sample groups allow to identify a set of discriminating genes that can be used for molecular markers for predicting development of cancer and/or dysplasia in ulcerative colitis, and to characterize potential diagnostic markers in UC-associated neoplasm. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
121 Samples

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Series

Accession:: GSE3629

ID:: 200003629

Select item 2000074104.

Gene expression in early stage cervical cancer

(Submitter supplied) Gene expression profiling of early stage cervical cancer tumours with and without lymph node metastasis, in order to predict lymph node metastasis before treatment. Subsequently, comparing gene expression profiles between healthy cervical tissue and early stage cervical cancer tissue. Keywords: Disease stage analysis

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL1708
45 Samples

Download data: TXT

Series

Accession:: GSE7410

ID:: 200007410

Select item 2000022805.

Prediction of lymphatic metastasis from primary squamous cell carcinoma of the oral cavity

(Submitter supplied) Metastasis via the lymphatics is a major risk factor in squamous cell carcinoma of the oral cavity (OSCC). We sought to determine whether the presence of metastasis in the regional lymph node could be predicted by a gene expression signature of the primary tumor. A total of 18 OSCCs were characterized for gene expression by hybridizing RNA to Affymetrix U133A gene chips. Genes with differential expression were identified using a permutation technique and verified by quantitative RT-PCR and immunohistochemistry. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS1062
Platform:: GPL96
27 Samples

Download data: CEL

Series

Accession:: GSE2280

ID:: 200002280

Select item 10626.

Squamous cell carcinoma of the oral cavity with lymph node metastasis

Expression profiling of 18 primary squamous cell carcinomas of the oral cavity with or without lymph node metastasis. Expression in lymph node metastasis also examined. Results used to identify gene expression signature in primary tumors that indicates the presence of lymph node metastasis.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 disease state, 2 tissue sets

Platform:: GPL96
Series:: GSE2280
27 Samples

Download data: CEL

DataSet

Accession:: GDS1062

ID:: 1062

Select item 2000112647.

A predictive and prognostic 38-gene expression signature for metastatic relapse in breast cancer

(Submitter supplied) Background Currently, no gene-expression signature (GES) established from node-positive cohorts, able to predict breast cancer evolution after systemic adjuvant chemotherapy, exists. Methods Gene-expression profiles of 252 node-positive patients (median follow-up: 7.7 years), mostly included in a randomized clinical trial (PACS01), receiving systemic adjuvant regimen, were determined by means of cDNA custom array representing 5,776 distinct genes. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL4819
252 Samples

Download data: TXT

Series

Accession:: GSE11264

ID:: 200011264

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000054608.

Predicting Features of Breast Cancer with Gene Expression Patterns

(Submitter supplied) Predictors built from gene expression data accurately predict ER, PR, and HER2 status, and divide tumor grade into high-grade and low-grade clusters; intermediate-grade tumors are not a unique group. In contrast, gene expression data cannot be used to predict tumor size or lymphatic-vascular invasion. Keywords: disease state analysis

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
129 Samples

Download data: CEL

Series

Accession:: GSE5460

ID:: 200005460

Select item 2000046769.

Gene expression profiles of oral tongue squamous cell carcinoma tissues.

(Submitter supplied) Gene expression profiles of oral tongue squamous cell carcinoma tissues. Keywords: human tongue cancer, brachytherapy, biopsy sample, primary tissues

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL2891
98 Samples

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Series

Accession:: GSE4676

ID:: 200004676

Select item 20000331210.

Expression Changes Relevant for Apoptosis in K562 Cells Co-Treated with Amifostine and Imatinib

(Submitter supplied) We had previously demonstrated an increased proapoptotic effect of Imatinib (STI571) in combination with Amifostine (AMI) in K562 cell line. In this study we used genomic scale gene expression profiling to monitor changes at transcriptional level in K562 cells during the treatment with AMI+STI571. We identified a transcriptional repressor of survival genes, known as BTF, which triggers a pro-apoptotic signal, potentially helpful to overcome the resistance to STI571. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL2829
4 Samples

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Series

Accession:: GSE3312

ID:: 200003312

Select item 20000329411.

Comparative study of gene expression in human colorectal cancer tissues and normal mucosa

(Submitter supplied) The purpose of our study was to better understand the genetic mechanism of oncogenesis for human colorectal cancer and to identify potential new tumour markers of use in clinical practice. Results: Comparing cancerous tissues with normal colonic mucosa we identified 584 known genes (3%) differentially expressed to a significant degree (p<0.001). Many of the transcripts that were more abundant in tumours than in non-neoplastic tissues appear to reflect important events for colon carcinogenesis. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL2829
24 Samples

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Series

Accession:: GSE3294

ID:: 200003294

Select item 20002317712.

Prediction of lymph node involvement in breast cancer from primary tumor tissue using gene expression profiling and miRNAs.

(Submitter supplied) Lymph node involvement is the most important prognostic factor in breast cancer, but little is known about the underlying molecular changes. First, to identify a molecular signature associated with nodal metastasis, gene expression analysis was performed on a homogeneous group of 96 primary breast tumors, balanced for lymph node involvement. Each tumor was diagnosed as a poorly differentiated, estrogen positive, her2-neu negative invasive ductal cancer. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
116 Samples

Download data: CEL

Series

Accession:: GSE23177

ID:: 200023177

Select item 20000349313.

Rectal Cancer Cells and Radiation-sensitivity

(Submitter supplied) Biopsy specimens were collected from rectal cancer before starting preoperative radiotherapy.The expression profiles were determined using Affymetrix Human Genome U95 version 2 arrays.Comparison between the sample groups allow to identify a set of discriminating genes that can be used for characterization of responders and nonresponders to preoperative radiotherapy in rectal cancer. Keywords: repeat

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS1887
Platform:: GPL8300
46 Samples

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Series

Accession:: GSE3493

ID:: 200003493

Select item 188714.

Rectal cancer cells and radiotherapy response

Analysis of rectal cancer cells from patients prior to preoperative radiotherapy. Response to radiotherapy determined by histopathologic examination of resected specimens. Results identify gene markers for the characterization and prediction of the response to radiotherapy in rectal cancer.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 disease state, 2 protocol sets

Platform:: GPL8300
Series:: GSE3493
46 Samples

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DataSet

Accession:: GDS1887

ID:: 1887

Select item 20000934815.

Expression data from healthy controls and early stage CRC patient's tumor

(Submitter supplied) Metastasis is the major cause of cancer mortality. Up to 25% of early stage sporadic colorectal cancer (CRC) patients succumb to metastasis after curative surgery. We used microarrays to detail gene expression and identified a metastasis-prone signature for early stage CRC. Keywords: RNA expression

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
82 Samples

Download data: CEL, CHP

Series

Accession:: GSE9348

ID:: 200009348

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