GEO DataSets

(Submitter supplied) Global gene expression in livers of primaquine treated mice was compared with control mice at different time points. Keywords: Time course

Organism:

Mus musculus

Type:

Expression profiling by array

Platforms:

GPL4389 GPL3493

7 Samples

Download data: TXT

(Submitter supplied) Global gene expression in livers of bulaquine treated mice was compared with control mice at different time points. Keywords: Time course

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL4389

12 Samples

Download data: TXT

(Submitter supplied) d-serine is naturally present throughout the human body. It is also used as add-on therapy for treatment-refractory schizophrenia. d-Serine interacts with the strychnine-insensitive glycine binding site of NMDA receptor, and this interaction could lead to potentially toxic activity (i.e., excitotoxicity) in brain tissue. The transcriptomic changes that occur in the brain after d-serine exposure have not been fully explored. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS3643

Platform:

GPL1355

24 Samples

Download data: CEL

Analysis of forebrains of animals treated with up to 500 mg/kg D-serine for 96 hours. D-serine is involved in many physiological processes through its interaction with the glycine binding site of the NMDA receptor. Results provide insight into the impact of D-serine exposure on neuronal functions.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent, 6 dose sets

Platform:

GPL1355

Series:

GSE10748

24 Samples

Download data: CEL

(Submitter supplied) RDX (Hexahydro-1,3,5-trinitro-1,3,5-triazine) is a synthetic, high-impact, relatively stable explosive that has been in use since WWII. Exposure to RDX can occur either occupationally or through ordnance that lays unexploded on training ranges. The toxicology of RDX is dominated by acute tonic-clonic seizures at high doses, which remit when exposure is removed and internal RDX levels decrease. Sub-chronic studies have revealed few other toxic effects. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Datasets:

GDS5282 GDS5283

Platform:

GPL1355

48 Samples

Download data: CEL

Analysis of livers of males for up to 48 hours after treatment with a single, oral, nonseizure-inducing dose of 3 or 18 mg/kg hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX). RDX is a synthetic, high-impact, stable explosive. Results provide insight into the acute effects of RDX on the liver.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 dose, 4 time sets

Platform:

GPL1355

Series:

GSE12196

24 Samples

Download data: CEL

Analysis of cerebral cortices of males for up to 48 hours after treatment with an oral, nonseizure-inducing dose of 3 or 18 mg/kg hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX). RDX is a synthetic, high-impact, stable explosive. Results provide insight into the acute effects of RDX on the brain.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 dose, 4 time sets

Platform:

GPL1355

Series:

GSE12196

24 Samples

Download data: CEL