Similar studies for GEO DataSets (Select 200006008) - GEO DataSets

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Items: 20

Select item 2000060081.

(Submitter supplied) 99 individual ovarian tumors (37 endometrioid, 41 serous, 13 mucinous, and 8 clear cell carcinomas) and 4 individual normal ovary samples, each assayed on an Affymetrix HG_U133A array Keywords: Individual tumor comparisons

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
103 Samples

Download data: CEL

Series

Accession:: GSE6008

ID:: 200006008

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000800852.

Oviductal vs. ovarian epithelial transformation yields very different tumor phenotypes in Apc fl/fl;Pten fl/fl mice

(Submitter supplied) We treated 6-8 week old mice that had floxed alleles of both Apc and Pten (for both alleles in each case) that also carry an Ovgp1-iCre-ERT2 transgene, with one of two treatments; a third group received neither treatment. The Ovgp1-iCre-ERT2 expresses Cre recombinase fused to a tamoxifen-inducible fragment of the estrogen receptor, in tissues where the Ovgp1 gene (oviductal glycoprotein 1) is expressed, which is almost exclusively in mouse oviductal epithelium (equivalent to human fallopian tube epithelium = FTE). more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL17400
15 Samples

Download data: CEL, TXT, XLSX

Series

Accession:: GSE80085

ID:: 200080085

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000059873.

Mouse model of Endometrioid Ovarian Adenocarcinomas by conditional inactivation of PTEN and APC genes

(Submitter supplied) Fifty million plaque-forming units of AdCre was injected into the right ovarian bursal cavity of 56- 70 day old female mice. Mice were euthanized 63 days later to obtain ovary tumors and normal ovary tissue. Seven individual ovarian tumors and 4 individual normal ovary samples were each assayed on an Affymetrix Mouse Genome 430 2.0 array. Keywords: Tumor vs normal comparisons

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1261
11 Samples

Download data: CEL

Series

Accession:: GSE5987

ID:: 200005987

Select item 2000035364.

Hepatoma cell lines vs. Universal control 3

(Submitter supplied) Gene expression profiles in hepatoma cells Keywords: Cell type comparison

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL2913
36 Samples

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Series

Accession:: GSE3536

ID:: 200003536

Select item 2000035115.

Hepatoma cell lines vs. Universal control 2

(Submitter supplied) Gene expression profiles in hepatoma cells Keywords: Cell type comparison

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL2912
18 Samples

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Series

Accession:: GSE3511

ID:: 200003511

Select item 2000034446.

Hepatoma cell lines vs. Universal control

(Submitter supplied) Gene expression profiles in hepatoma cells Keywords: Cell type comparison

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL2911
18 Samples

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Series

Accession:: GSE3444

ID:: 200003444

Select item 2000676957.

Effects of Arid1a knockout in murine ovarian endometrioid carcinomas with biallelic inactivation of Apc and Pten

(Submitter supplied) We mated mice with floxed alleles of both Apc and Pten, to mice with floxed alleles for Arid1a, to obtain female mice with both copies of all three genes floxed. At 7 to 8 weeks of age the right ovarian bursal cavites of the mice were injected with 50 million plaque-forming units of adenovirus expressing Cre recombinase, which causes the floxed genes to be knocked out. Tumor tissue from 3 mice for each group was obtained at necropsy, RNA purified, and targets for Affymetrix arrays synthesized from the mRNAs. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1261
6 Samples

Download data: CEL, XLSX

Series

Accession:: GSE67695

ID:: 200067695

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000018998.

Targets of Wnt-1 in C57MG

(Submitter supplied) RNA from murine mammary C57MG cells transfected with an empty control vector (PLNCx) or an expression vector encoding Wnt-1 was isolated and analyzed on Affymetrix MG-U74Av2 arrays. Sample preparation was done as recommended by the manufacturer. Images were analyzed using Affymetrix Microarray Suite 4.0 software. Comparison of Wnt-1 expressing and control cells revealed Wnt-1 targets. Keywords: ordered

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL81
2 Samples

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Series

Accession:: GSE1899

ID:: 200001899

Select item 2000820079.

caArray_liu-00258: Gene expression profiles of BRCA1-linked, BRCA2-linked, and sporadic ovarian cancers

(Submitter supplied) We used complementary DNA (cDNA) microarrays to compare gene expression patterns in ovarian cancers associated with BRCA1 or BRCA2 mutations with gene expression patterns in sporadic epithelial ovarian cancers and to identify patterns common to both hereditary and sporadic tumors.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL21962
61 Samples

Download data: GPR

Series

Accession:: GSE82007

ID:: 200082007

PubMed Similar studies

Select item 20013559010.

mRNA-seq data for mouse ovarian tumors arising from oviduct with combinations of (Tamoxifen-inducible) inactivation of Brca1, Trp53, Rb1, and Nf1, or Apc and Pten, and normal ovaries and oviducts.

(Submitter supplied) We engineered mice to have Ovgp1 promotor-driven expression of a tamoxifen-inducible Cre recombinase (iCre-ERT2), which inactivated the function of combinations of engineered floxed alleles of combinations of tumor suppressor genes in mouse oviducts (Fallopian tube) when mice were treated with tamoxifen. 21 samples were from oviductal tumors from mice with combinations of floxed alleles of Brca1, Trp53, Rb1, and/or Nf1 (BPRN mice), of which we analyzed 19. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21103
35 Samples

Download data: TXT, XLSX

Series

Accession:: GSE135590

ID:: 200135590

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20006860011.

caArray_cho-00156: Gene Expression in Ovarian Cancer Reflects Both Morphology and Biological Behavior

(Submitter supplied) Biologically and clinically meaningful tumor classification schemes have long been sought. Some malignant epithelial neoplasms, such as those in the thyroid and endometrium, exhibit more than one pattern of differentiation, each associated with distinctive clinical features and treatments. In other tissues, all carcinomas, regardless of morphological type, are treated as though they represent a single disease. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL80
113 Samples

Download data: CEL, TXT

Series

Accession:: GSE68600

ID:: 200068600

Select item 20001279012.

Gene expression profiling of human breast cancers and cancer cell lines

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
98 Samples

Download data: CEL

Series

Accession:: GSE12790

ID:: 200012790

Select item 20001277713.

Gene expression profiling of 51 human breast cancer cell lines

(Submitter supplied) Basal gene expression levels were determined by global gene expression profiling of breast cancer cell lines. Molecular subtype was determined using gene expression and HER2 status assesses by HER2 FISH analysis. Keywords: Basal gene expression (no stimulation or timecourse)

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
51 Samples

Download data: CEL

Series

Accession:: GSE12777

ID:: 200012777

Select item 20001276414.

Gene expression changes upon expression of activated versions of MEK1 and HRAS in MCF10A cells

(Submitter supplied) MCF10A cells were then transfected with MEK1(S217S221), HRAS(G12V), and null control vectors Cells were lysed 24 hours post-transfection with collection of total RNA and protein Keywords: Oncogene inducation of gene expression changes

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
17 Samples

Download data: CEL

Series

Accession:: GSE12764

ID:: 200012764

Select item 20001276315.

Gene expression profiling of 30 human breast cancers

(Submitter supplied) We used microarrays to profile 30 human primary breast tumors and determine global gene expression patterns and molecular subtypes Keywords: Basal gene expression in human tumor samples

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
30 Samples

Download data: CEL

Series

Accession:: GSE12763

ID:: 200012763

Select item 20010636216.

PTEN loss in the fallopian tube induces hyperplasia and ovarian tumor formation

(Submitter supplied) The goals of this study are to compare mouse oviductal transcriptome profiling (RNA-seq) of PTEN-depleted cells by shRNA versus a scr shRNA control expressing PTEN.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17021
6 Samples

Download data: TXT

Series

Accession:: GSE106362

ID:: 200106362

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20001805417.

Gene Expression Profiles of a Progression Model of Human Ovarian Cancer

(Submitter supplied) We have earlier reported the establishment of a comprehensive in vitro panel of 19 isogenic cell lines from a patient with Grade IV serous adenocarcinoma (Bapat et al. Cancer Research. 2005). In this study, one of the cell lines termed as A4 at early passes (less than ~20) was assessed as being non-tumorigenic since it failed to exhibit anchorage independence growth in soft agar and form tumors in nude mice. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6480
3 Samples

Download data: TXT, XLS

Series

Accession:: GSE18054

ID:: 200018054

Select item 20000147318.

Beta-catenin/GFP

(Submitter supplied) 293 cells, infected with RCAS-beta-cateninS37A or RCAS-GFP Keywords = 293cells Keywords = beta catenin Keywords: repeat sample

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS748
Platform:: GPL96
8 Samples

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Series

Accession:: GSE1473

ID:: 200001473

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 74819.

Beta-catenin S37A mutant effect on gene expression

Expression profiling of 293T cells infected with RCAS vector carrying beta-catenin S37A mutant. Beta-catenin S37A mutant is oncogenic and more stable than the corresponding wild type protein.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 cell line sets

Platform:: GPL96
Series:: GSE1473
8 Samples

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DataSet

Accession:: GDS748

ID:: 748

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 20012501620.

Both Fallopian Tube and Ovarian Surface Epithelium Can Act as Cell-of-Origin for High Grade Serous Ovarian Carcinoma

(Submitter supplied) The cell-of-origin of high grade serous ovarian carcinoma (HGSOC) remains controversial, with fallopian tube epithelium (FTE) and ovarian surface epithelium (OSE) both considered candidates. Here, by using genetically engineered mouse models and organoids, we assessed the tumor-forming properties of FTE and OSE harboring the same oncogenic abnormalities. Combined RB family inactivation and Tp53 mutation in Pax8+ FTE caused Serous Tubal Intraepithelial Carcinoma (STIC), which metastasized rapidly to the ovarian surface. more...