Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO DataSets

Items: 12

1.

Expression data from brains of mice fed four different diets

(Submitter supplied) Beyond the DNA sequence difference between humans and closely related apes, there are large differences in the environments that these species experience. One prominent example for this is diet. The human diet diverges from those of other primates in various aspects, such as having a high calorie and protein content, as well as being cooked. Here, we used a laboratory mouse model to identify gene expression differences related to dietary differences. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS3232
Platform:
GPL1261
24 Samples
Download data: CEL
Series
Accession:
GSE6285
ID:
200006285
2.

Expression data from livers of mice fed four different diets

(Submitter supplied) Beyond the DNA sequence difference between humans and closely related apes, there are large differences in the environments that these species experience. One prominent example for this is diet. The human diet diverges from those of other primates in various aspects, such as having a high calorie and protein content, as well as being cooked. Here, we used a laboratory mouse model to identify gene expression differences related to dietary differences. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS3221
Platform:
GPL1261
24 Samples
Download data: CEL
Series
Accession:
GSE6297
ID:
200006297
3.
Full record GDS3232

Brain response to human and chimpanzee diets

Analysis of brains from NMR1 females fed human and chimpanzee diets for 2 weeks. The human diet is markedly different from the diets of closely related primate species. Results provide insight into the influence of different diets on gene expression patterns in brain.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 4 protocol sets
Platform:
GPL1261
Series:
GSE6285
24 Samples
Download data: CEL
4.
Full record GDS3221

Liver response to human and chimpanzee diets

Analysis of livers from NMR-1 females fed human and chimpanzee diets for 2 weeks. Human diet is markedly different from the diets of closely related primate species. Results provide insight into the influence of different diets on gene expression patterns.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 4 protocol sets
Platform:
GPL1261
Series:
GSE6297
24 Samples
Download data: CEL
5.

Evolutionary Significance of DNA Methylation in Human and Chimpanzee Brains

(Submitter supplied) We compared the genome-wide patterns of DNA methylation in the brains of humans to those of our closest evolutionary relative, chimpanzees, using base-pair resolution whole-genome methylation maps of the prefrontal cortex. Our data reveal that the prefrontal cortex is the most heavily methylated among the human tissues examined so far. Nevertheless, hundreds of genes exhibit dramatically reduced levels of promoter DNA methylation in the human brain relative to the chimpanzee brain. more...
Organism:
Pan troglodytes; Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platforms:
GPL15434 GPL9115 GPL15433
6 Samples
Download data: GFF
Series
Accession:
GSE37202
ID:
200037202
6.

Human-specific patterns of gene expression in the brain

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Macaca mulatta; Homo sapiens; Pan troglodytes
Type:
Expression profiling by array; Expression profiling by high throughput sequencing
5 related Platforms
92 Samples
Download data: CEL, TXT
Series
Accession:
GSE33588
ID:
200033588
7.

Human-specific patterns of gene expression in the brain (RNA-Seq)

(Submitter supplied) We identified human-specific gene expression patterns in the brain by comparing expression with chimpanzee and rhesus macaque.
Organism:
Macaca mulatta; Homo sapiens; Pan troglodytes
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL9378 GPL9115 GPL9160
44 Samples
Download data: TXT
Series
Accession:
GSE33587
ID:
200033587
8.

Human-specific patterns of gene expression in the brain (Arrays)

(Submitter supplied) We identified human-specific gene expression patterns in the brain by comparing expression with chimpanzee and rhesus macaque
Organism:
Macaca mulatta; Pan troglodytes; Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL570 GPL3535
48 Samples
Download data: CEL, TXT
Series
Accession:
GSE33010
ID:
200033010
9.

A Genome-wide Study of DNA Methylation Patterns and Gene Expression Levels in Multiple Human and Chimpanzee Tissues

(Submitter supplied) It has long been hypothesized that changes in gene regulation have played an important role in primate evolution. However, despite the wealth of comparative gene expression data, there are still only few studies that focus on the mechanisms underlying inter-primate differences in gene regulation. In particular, we know relatively little about the degree to which changes in epigenetic profiles might explain differences in gene expression levels between primates. more...
Organism:
Homo sapiens; Pan troglodytes
Type:
Methylation profiling by array
Platform:
GPL8490
71 Samples
Download data: TXT
Series
Accession:
GSE26033
ID:
200026033
10.

Gene expression analysis of the human and chimpanzee brain

(Submitter supplied) The origin of humans was accompanied by the emergence of new behavioral and cognitive functions, including language and specialized forms of abstract representation. However, the molecular foundations of these human capabilities are poorly understood. Because of the extensive similarity between human and chimpanzee DNA sequences, it has been suggested that many of the key phenotypic differences between species result primarily from alterations in the regulation of genes rather than in their sequences. more...
Organism:
Pan troglodytes; Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS2678
Platform:
GPL8300
37 Samples
Download data: CEL, CHP, EXP
Series
Accession:
GSE7540
ID:
200007540
11.
Full record GDS2678

Brain regions of humans and chimpanzees

Comparison of various human and chimpanzee brain regions. Results provide insight into the genetic basis of human specializations in brain organization and cognition.
Organism:
Pan troglodytes; Homo sapiens
Type:
Expression profiling by array, count, 2 species, 12 tissue sets
Platform:
GPL8300
Series:
GSE7540
37 Samples
Download data: CEL, CHP, EXP
12.

MicroRNA expression and regulation in human, chimpanzee, and macaque brain

(Submitter supplied) Among other factors, changes in gene expression on the human evolutionary lineage have been suggested to play an important role in the establishment of human-specific phenotypes. However, the molecular mechanisms underlying these expression changes are largely unknown. Here, we have explored the role of microRNA (miRNA) in the regulation of gene expression divergence between adult humans, chimpanzees and rhesus macaques, in two brain regions: prefrontal cortex and cerebellum. more...
Organism:
Macaca mulatta; Homo sapiens; Pan troglodytes
Type:
Expression profiling by array; Non-coding RNA profiling by array; Non-coding RNA profiling by high throughput sequencing
6 related Platforms
46 Samples
Download data: CEL, TXT
Series
Accession:
GSE26545
ID:
200026545
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=|query=1|qty=5|blobid=MCID_617927b351cad3136140a61a|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center